EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.3.15 | (S)-2-hydroxy-acid oxidase |
hepatocyte |
- |
-, 741999 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
hepatocyte |
- |
675007, 757194 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
hepatocyte |
primary |
756896 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
hepatocyte |
- |
650326, 680904, 80955 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
hepatocyte |
secretion of plasma isozyme |
653695 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
hepatocyte |
- |
740024 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
hepatocyte |
primary |
668379 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
hepatocyte |
primary |
668379 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
hepatocyte |
- |
735755, 757542 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
hepatocyte |
primary |
735610 |
4.1.2.63 | 2-hydroxyacyl-CoA lyase |
hepatocyte |
- |
760638, 761438 |
1.2.1.23 | 2-oxoaldehyde dehydrogenase (NAD+) |
hepatocyte |
- |
288139 |
1.14.14.29 | 25/26-hydroxycholesterol 7alpha-hydroxylase |
hepatocyte |
- |
658874, 688678 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
hepatocyte |
- |
750283 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
hepatocyte |
- |
761948 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
hepatocyte |
- |
349052 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
hepatocyte |
primary, high expression and activity in healthy hepatocytes |
675595 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
hepatocyte |
primary, high expression and activity in healthy hepatocytes |
675595 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
hepatocyte |
- |
741250 |
1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
hepatocyte |
primary cultured hepatocyte |
741250 |
1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
hepatocyte |
primary, time-dependent reduction of tibolone into 3beta- and 3alpha-hydroxytibolone was observed again in a 4:1 ratio |
675595 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
hepatocyte |
- |
639533 |
1.14.13.29 | 4-nitrophenol 2-monooxygenase |
hepatocyte |
- |
673929 |
1.14.14.139 | 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase |
hepatocyte |
- |
727973 |
1.14.14.139 | 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase |
hepatocyte |
mainly expressed in |
658876 |
1.14.14.139 | 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase |
hepatocyte |
primary |
677257, 688559 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
- |
-, 640281, 640294, 737752 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
coordinate roles for glucokinase and PFK2 in the elevated hepatic glycolysis in fa/fa rats |
671260 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
primary culture |
661569 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
primary culture, treated and untreated with adenoviral vector to overexpress wild-type PFK-2 and mutant PKF2-M lacking Ser-32 phosphorylation site |
684366 |
7.6.2.3 | ABC-type glutathione-S-conjugate transporter |
hepatocyte |
- |
746704, 747225 |
7.6.2.2 | ABC-type xenobiotic transporter |
hepatocyte |
- |
210385, 210386, 695397, 747448, 747619 |
6.2.1.16 | acetoacetate-CoA ligase |
hepatocyte |
primary |
-, 720477 |
3.1.2.1 | acetyl-CoA hydrolase |
hepatocyte |
- |
94484 |
3.1.3.2 | acid phosphatase |
hepatocyte |
enzyme does not appear in other cells of liver tissue |
649089 |
1.14.19.3 | acyl-CoA 6-desaturase |
hepatocyte |
treatment with myristic acid specifically increases DELTA6-desaturase activity |
660486 |
1.14.19.31 | acyl-lipid (7-3)-desaturase |
hepatocyte |
- |
744399 |
3.1.1.23 | acylglycerol lipase |
hepatocyte |
- |
729792 |
3.4.24.87 | ADAMTS13 endopeptidase |
hepatocyte |
ADAMTS13 and von Willebrand factor contents, overview |
713533 |
2.7.1.20 | adenosine kinase |
hepatocyte |
- |
738347 |
2.7.4.3 | adenylate kinase |
hepatocyte |
in primary culture |
673004 |
2.6.1.44 | alanine-glyoxylate transaminase |
hepatocyte |
- |
640075, 640086, 758712 |
1.1.1.1 | alcohol dehydrogenase |
hepatocyte |
- |
655233 |
1.1.1.1 | alcohol dehydrogenase |
hepatocyte |
the activities of total alcohol dehydrogenase, aldehyde dehydrogenase and class I alcohol dehydrogenase isoenzyme between cancer liver tissues and healthy hepatocytes might be a factor in ethanol metabolism disorders which can intensify carcinogenesis |
687976 |
2.8.2.2 | alcohol sulfotransferase |
hepatocyte |
- |
-, 645741, 645782, 645783, 645790, 760454, 761897 |
2.8.2.2 | alcohol sulfotransferase |
hepatocyte |
primary culture |
693816 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
hepatocyte |
- |
686331, 712069 |
1.2.3.1 | aldehyde oxidase |
hepatocyte |
- |
724829 |
1.2.3.1 | aldehyde oxidase |
hepatocyte |
ABCA1 and AOX1 are coexpressed |
692569 |
1.2.3.1 | aldehyde oxidase |
hepatocyte |
primary hepatocyte |
671778 |
1.1.1.21 | aldose reductase |
hepatocyte |
- |
739478 |
3.1.3.1 | alkaline phosphatase |
hepatocyte |
fetal |
690297 |
3.1.3.1 | alkaline phosphatase |
hepatocyte |
primary cultures of fetal rat hepotocytes are used |
690297 |
1.14.15.3 | alkane 1-monooxygenase |
hepatocyte |
- |
702154 |
1.3.99.23 | all-trans-retinol 13,14-reductase |
hepatocyte |
primary |
-, 763507 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
hepatocyte |
- |
704793 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
hepatocyte |
primary |
659759 |
3.2.1.22 | alpha-galactosidase |
hepatocyte |
- |
136489 |
4.1.1.45 | aminocarboxymuconate-semialdehyde decarboxylase |
hepatocyte |
- |
692185, 692186, 727425 |
2.6.1.43 | aminolevulinate transaminase |
hepatocyte |
- |
640059 |
3.2.1.33 | amylo-alpha-1,6-glucosidase |
hepatocyte |
primary culture |
696731 |
3.6.1.5 | apyrase |
hepatocyte |
restricted to the canalicular membrane domain of hepatocytes |
-, 718543 |
1.13.11.34 | arachidonate 5-lipoxygenase |
hepatocyte |
- |
-, 688231 |
3.5.3.1 | arginase |
hepatocyte |
24h culture, both enzyme and NOS-2 activity depend strongly on extracellular L-arginine concentrations. Competing for L-arginine influx by addition of L-lysine results in 60-70% inhibition of enzyme. Addition of enzyme inhibitor L-valine to cells leads to 80-90% decrease in enzyme activity and 25% increase in NOS-2 activity |
670421 |
3.5.3.1 | arginase |
hepatocyte |
type I |
701646 |
4.3.2.1 | argininosuccinate lyase |
hepatocyte |
ASL expression is time-dependently reduced in hypoxia |
652664 |
6.3.4.5 | argininosuccinate synthase |
hepatocyte |
- |
692607 |
2.1.1.137 | arsenite methyltransferase |
hepatocyte |
- |
658442 |
2.1.1.137 | arsenite methyltransferase |
hepatocyte |
primary |
673463 |
2.3.1.5 | arylamine N-acetyltransferase |
hepatocyte |
- |
755741 |
3.1.8.1 | aryldialkylphosphatase |
hepatocyte |
PON1 |
692441 |
3.1.6.1 | arylsulfatase (type I) |
hepatocyte |
- |
709806 |
2.6.1.1 | aspartate transaminase |
hepatocyte |
- |
759587 |
2.3.3.8 | ATP citrate synthase |
hepatocyte |
ACLY deficiency in hepatocytes protects from hepatic steatosis and dyslipidemia |
758267 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
hepatocyte |
different expression level in fetal and adult hepatocytes |
638227 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
hepatocyte |
primary |
638227 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
hepatocyte |
very low amount |
638223, 638227 |
2.7.11.15 | beta-adrenergic-receptor kinase |
hepatocyte |
- |
674831 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
hepatocyte |
- |
-, 728342, 744161, 745597 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
hepatocyte |
- |
637284 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
hepatocyte |
- |
686836 |
2.1.1.5 | betaine-homocysteine S-methyltransferase |
hepatocyte |
- |
671242, 687005, 704793, 733401, 755939 |
2.3.1.65 | bile acid-CoA:amino acid N-acyltransferase |
hepatocyte |
- |
673916, 706769 |
3.5.1.12 | biotinidase |
hepatocyte |
- |
171935 |
3.4.22.40 | bleomycin hydrolase |
hepatocyte |
detected by immunohistochemistry |
683613 |
2.6.1.42 | branched-chain-amino-acid transaminase |
hepatocyte |
- |
640019, 640037 |
3.4.22.52 | calpain-1 |
hepatocyte |
- |
709967 |
3.4.22.53 | calpain-2 |
hepatocyte |
- |
709329 |
2.7.11.11 | cAMP-dependent protein kinase |
hepatocyte |
- |
762105 |
6.3.4.16 | carbamoyl-phosphate synthase (ammonia) |
hepatocyte |
- |
1457, 672441, 673597, 691725 |
6.3.4.16 | carbamoyl-phosphate synthase (ammonia) |
hepatocyte |
cultured human primary hepatocytes, express CPS1 at abundant levels |
713715 |
6.3.5.5 | carbamoyl-phosphate synthase (glutamine-hydrolysing) |
hepatocyte |
primary mouse hepatocytes release CPS1 during Fas ligand-induced apoptotic injury, and CPS1 is detected in hepatocytes upon hypoosmotic stress |
743989 |
4.2.1.1 | carbonic anhydrase |
hepatocyte |
carbonic anhydrase XIV |
679413 |
3.1.1.1 | carboxylesterase |
hepatocyte |
- |
690745 |
2.3.1.137 | carnitine O-octanoyltransferase |
hepatocyte |
- |
486301 |
2.3.1.21 | carnitine O-palmitoyltransferase |
hepatocyte |
- |
684341, 688981 |
3.4.22.55 | caspase-2 |
hepatocyte |
- |
753185 |
3.4.22.56 | caspase-3 |
hepatocyte |
- |
698258, 701153 |
3.4.22.59 | caspase-6 |
hepatocyte |
- |
698943 |
3.4.22.59 | caspase-6 |
hepatocyte |
primary |
698943 |