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Literature summary for 4.1.1.45 extracted from

  • Sasaki, N.; Egashira, Y.; Sanada, H.
    Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalpha (2008), Eur. J. Nutr., 47, 80-86.
    View publication on PubMed
Search for more literature for 4.1.1.45

Inhibitors

Inhibitors Comment Organism Structure
eicosapentaenoic acid ACMSD mRNA levels in primary hepatocytes are decreased by the incubation with high concentrations of eicosapentaenoic acid Rattus norvegicus
linoleic acid ACMSD mRNA levels in primary hepatocytes are decreased by the incubation with high concentrations of linoleic acid Rattus norvegicus
additional information MK886 does not influence the suppressive effects of polyunsaturated fatty acids on ACMSD activity Rattus norvegicus
WY-14,643 ACMSD mRNA levels in primary hepatocytes are decreased by the incubation with high concentrations of WY-14,643 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus key enzyme in NAD biosynthesis from tryptophan ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate
-
 Rattus norvegicus 2-aminomuconate semialdehyde + CO2
-
 ?
additional information key enzyme in NAD biosynthesis from tryptophan Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
ACMSD
-
 Rattus norvegicus
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
-
 Rattus norvegicus