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Information on EC 1.13.11.34 - arachidonate 5-lipoxygenase

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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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Synonyms
5-lipoxygenase, 5-lox, leukotriene a4 synthase, lox-5, lta synthase, arachidonic acid 5-lipoxygenase, 5-lo1, pmnl 5-lipoxygenase, arachidonate 5-lo, lipoxygenase 5, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyicosa-6,8,11,14-tetraenoate = leukotriene A4 + H2O
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(1b)
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arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyicosa-6,8,11,14-tetraenoate
show the reaction diagram
arachidonate + O2 = leukotriene A4 + H2O
show the reaction diagram
overall reaction
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