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aldehyde dehydrogenase (NAD)
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-
aldehyde dehydrogenase 1
-
-
aldehyde dehydrogenase 16
aldehyde dehydrogenase 1A1
aldehyde dehydrogenase 1A3
-
-
aldehyde dehydrogenase 1B1
-
isoform
aldehyde dehydrogenase 3A1
-
-
aldehyde dehydrogenase 7A1
aldehyde dehydrogenase class 1
-
-
aldehyde dehydrogenase type 2
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Aldehyde dehydrogenase [NAD+]
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-
-
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Aldehyde dehydrogenase, cytosolic
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-
-
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Aldehyde dehydrogenase, microsomal
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-
-
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aldehyde dehydrogenase7
-
aldehyde:NAD+ oxidoreductase
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-
-
-
Aldh1a2
-
previously known as retinaldehyde dehydrogenase 2
Allergen Alt a 10
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-
-
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aryl-aldehyde dehydrogenases
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-
benzaldehyde dehydrogenase
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-
Brassica turgor-responsive/drought-induced gene 26 protein
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-
-
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class 1 aldehyde dehydrogenase
class 2 aldehyde dehydrogenase
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CoA-independent aldehyde dehydrogenase
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-
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coniferyl-aldehyde dehydrogenase
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-
EC 1.1.1.70
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-
formerly
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gamma-aminobutyraldehyde dehydrogenase
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-
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irreversible NAD+-dependent aldehyde dehydrogenase
K(+)-activated acetaldehyde dehydrogenase
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-
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m-methylbenzaldehyde dehydrogenase
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-
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Matured fruit 60 kDa protein
-
-
-
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Mg(2+)-activated acetaldehyde dehydrogenase
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-
-
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mitochondrial aldehyde dehydrogenase
NAD+-dependent aldehyde dehydrogenase
NAD+-linked aldehyde dehydrogenase
-
-
-
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NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase
NAD-aldehyde dehydrogenase
NAD-dependent 4-hydroxynonenal dehydrogenase
-
-
-
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NAD-dependent aldehyde dehydrogenase
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-
-
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NAD-linked aldehyde dehydrogenase
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-
-
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phenylacetaldehyde dehydrogenase
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phosphonoacetaldehyde dehydrogenase
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phosphonoacetaldehyde oxidase
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propionaldehyde dehydrogenase
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-
-
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R-aminobutyraldehyde dehydrogenase
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-
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Retinal dehydrogenase
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-
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retinal dehydrogenase type I
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salvery aldehyde dehydrogenase
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Turgor-responsive protein 26G
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-
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ADH
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-
AdhE
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bifunctional protein with alcohol dehydrogenase and aldehyde dehydrogenase activities
AdhE
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bifunctional protein with alcohol dehydrogenase and aldehyde dehydrogenase activities
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AdhE
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bifunctional protein with alcohol dehydrogenase and aldehyde dehydrogenase activities
AdhE
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bifunctional protein with alcohol dehydrogenase and aldehyde dehydrogenase activities
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ALD6
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ALDDH
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-
-
-
aldehyde dehydrogenase
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-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
-
-
aldehyde dehydrogenase
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-
aldehyde dehydrogenase 16
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aldehyde dehydrogenase 16
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-
aldehyde dehydrogenase 1A1
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-
aldehyde dehydrogenase 1A1
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isoform
aldehyde dehydrogenase 1A1
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aldehyde dehydrogenase 2
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aldehyde dehydrogenase 2
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aldehyde dehydrogenase 2
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aldehyde dehydrogenase 6
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aldehyde dehydrogenase 6
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aldehyde dehydrogenase 7A1
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aldehyde dehydrogenase 7A1
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aldehyde dehydrogenase 7A1
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aldehyde dehydrogenase-2
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aldehyde dehydrogenase-2
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aldehyde dehydrogenase-2
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-
ALDH
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-
ALDH
-
-
672780, 672818, 686331, 689316, 691973, 692225, 692542, 692781, 693946, 695926, 696996, 697567, 697569, 697802, 710796
ALDH-2
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-
ALDH1
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-
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ALDH16
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ALDH1A1
-
-
Aldh1a3
-
-
Aldh1b1
-
isoform
Aldh1b1
isoform, formerly known as ALDHx or ALDH5
ALDH2
-
-
ALDH2(2)
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mutant enzyme
ALDH2B8
-
ALDH3A1
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-
ALDH3A2
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isozyme
ALDH3H1
-
cytosolic isoform
Aldh7a1
-
-
Aldh8a1
-
ALDHTt
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Bt-Aldh
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class 1 aldehyde dehydrogenase
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class 1 aldehyde dehydrogenase
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class I ALDH
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irreversible NAD+-dependent aldehyde dehydrogenase
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irreversible NAD+-dependent aldehyde dehydrogenase
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mitochondrial aldehyde dehydrogenase
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mitochondrial aldehyde dehydrogenase
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NAD+-dependent aldehyde dehydrogenase
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NAD+-dependent aldehyde dehydrogenase
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-
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NAD+-dependent ALDH
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NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase
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NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase
-
-
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NAD+-specific ALDH
-
-
NAD-aldehyde dehydrogenase
-
-
-
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NAD-aldehyde dehydrogenase
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-
PhnN
-
phnY
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PuuC
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-
RalDH1
-
-
-
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ThnG
-
-
TTC0513
-
YneI
-
additional information
cf. EC 1.2.1.5
additional information
cf. EC 1.2.1.5
-
additional information
cf. EC 1.2.1.5
-
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(2E)-4-hydroxy-2-nonenal + NAD+ + H2O
(2E)-4-hydroxy-2-nonenoic acid + NADH + H+
(E)-2-nonenal + NAD+ + H2O
(E)-non-2-enoate + NADH + H+
-
-
-
-
?
(R)-N-(3-(6-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo[b] thiophene-2-carboxamide + H2O + O2
?
i.e. GDC-0834, a Bruton's tyrosine kinase inhibitor, a potential treatment of rheumatoid arthritis. GDC-0834
compound is extensively metabolized by amide hydrolysis by both aldehyde oxidase and carboxylesterase
-
?
(R)-trans-4-hydroxy-2-nonenal + NAD+ + H2O
(2E,4R)-4-hydroxynon-2-enoic acid + NADH + H+
(S)-trans-4-hydroxy-2-nonenal + NAD+ + H2O
(2E,4S)-4-hydroxynon-2-enoic acid + NADH + H+
-
-
-
?
1,3-dihydroxyacetone + NAD+ + H2O
? + NADH + H+
-
53.93% activity compared to acetaldehyde
-
-
?
1-formyl-6-methylpyrene + NAD+
6-methylpyrene 1-carboxylate + NADH + H+
-
-
-
?
1-formyl-6-methylpyrene + NAD+ + H2O
6-methylpyrene-1-carboxylic acid + NADH + H+
-
-
-
?
1-formyl-8-methylpyrene + NAD+ + H2O
8-methylpyrene-1-carboxylic acid + NADH + H+
-
-
-
?
1-formyl-8-methylpyrene + NADP+
8-methylpyrene 1-carboxylate + NADPH + H+
-
-
-
?
1-formylpyrene + NAD+
pyrene 1-carboxylate + NADH + H+
-
-
-
?
1-formylpyrene + NAD+ + H2O
pyrene-1-carboxylic acid + NADH + H+
-
-
-
?
1-naphthaldehyde + NAD+ + H2O
1-naphthoic acid + NADH
46.9% activity compared to p-tolualdehyde
-
-
?
1-naphthaldehyde + NAD+ + H2O
1-naphthoic acid + NADH + H+
-
-
-
-
?
2,4-dinitrobenzaldehyde + NAD+ + H2O
2,4-dinitrobenzoate + NADH
-
-
-
-
?
2-chlorobenzaldehyde + NAD+ + H2O
2-chlorobenzoate + NADH + H+
-
28.35% activity compared to formaldehyde
-
-
?
2-formylpyrene + NAD+
pyrene 2-carboxylate + NADH + H+
-
-
-
?
2-formylpyrene + NAD+ + H2O
pyrene-2-carboxylic acid + NADH + H+
-
-
-
?
2-furaldehyde + NAD+ + H2O
2-furanoic acid + NADH + H+
2-hydroxy-3-nitrobenzaldehyde + NAD+ + H2O
2-hydroxy-3-nitrobenzoic acid + NADH + H+
2-naphthaldehyde + NAD+ + H2O
2-naphthalene carboxylate + NADH + H+
-
-
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoate + NADH
-
-
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoic acid + NADH
48.8% activity compared to p-tolualdehyde
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoic acid + NADH + H+
-
-
-
-
?
2-nonenal + NAD+ + H2O
(E)-non-2-enoate + NADH + H+
-
-
-
-
?
2-phthalaldehyde + NAD+ + H2O
phthalate + NADH + H+
-
10.81% activity compared to formaldehyde
-
-
?
2-quinolinone-4-carboxaldehyde + NAD+ + H2O
2-quinolinone-4-carboxylate + NADH
-
-
-
-
?
3,4,5-trimethoxybenzaldehyde + NAD+ + H2O
3,4,5-trimethoxybenzoic acid + NADH + H+
-
-
-
-
?
3,4-dihydroxybenzaldehyde + NAD+ + H2O
3,4-dihydroxybenzoic acid + NADH + H+
-
-
-
-
?
3,4-dihydroxymandelic aldehyde + NAD+ + H2O
3,4-dihydroxymandelate + NADH
-
-
-
-
?
3,4-dihydroxyphenyl acetaldehyde + NAD+ + H2O
3,4-dihydroxyphenylacetate + NADH
-
-
-
-
?
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O
3,4-dihydroxyphenylacetate + NADH + H+
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O
3,4-dihydroxyphenylacetic acid + NADH + H+
-
-
-
-
?
3,4-dihydroxyphenylglycolaldehyde + NAD+ + H2O
3,4-dihydroxyphenylglycolate + NADH + H+
-
-
-
?
3,4-dimethoxy-5-hydroxybenzaldehyde + NAD+ + H2O
3,4-dimethoxy-5-hydroxybenzoic acid + NADH + H+
-
-
-
-
?
3,4-dimethoxybenzaldehyde + NAD+ + H2O
3,4-dimethoxybenzoate + NADH
-
-
-
-
?
3,4-dimethoxybenzaldehyde + NAD+ + H2O
3,4-dimethoxybenzoic acid + NADH + H+
-
-
-
-
?
3-hydroxy-4-methoxybenzaldehyde + NAD+ + H2O
3-hydroxy-4-methoxybenzoate + NADH + H+
-
-
-
-
?
3-hydroxypropaldehyde + NAD+ + H2O
3-hydroxypropionate + NADH + H+
-
-
-
-
?
3-hydroxypropanal + NAD+ + H2O
3-hydroxypropionate + NADH + H+
3-hydroxypropanoate + NADH + 2 H+
3-hydroxypropionaldehyde + NAD+ + H2O
-
-
-
-
r
3-hydroxypropionaldehyde + NAD+ + H2O
3-hydroxypropanoate + NADH + 2 H+
3-hydroxypropionaldehyde + NAD+ + H2O
3-hydroxypropionic acid + NADH + H+
3-methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O
3-methoxy-4-hydroxyphenylacetate + NADH + H+
-
-
-
-
?
3-nitrobenzaldehyde + NAD+ + H2O
3-nitrobenzoate + NADH + H+
-
32.98% activity compared to acetaldehyde
-
-
?
3-oxopropyl phosphonate + NAD+ + H2O
?
-
-
-
?
3-oxopropylphosphonate + NAD+ + H2O
?
-
-
-
?
3-pyridinecarboxaldehyde + NAD+ + H2O
3-pyridinecarboxylate + NADH
-
-
-
-
?
4-aminobutyraldehyde + NAD+ + H2O
4-aminobutyrate + NADH
-
-
-
-
?
4-carboxybenzaldehyde + NAD+ + H2O
4-carboxybenzoate + NADH
-
-
-
-
?
4-chlorobenzaldehyde + NAD+ + H2O
4-chlorobenzoate + NADH
-
-
-
-
?
4-chlorophenylacetaldehyde + NAD+ + H2O
4-chlorophenylacetate + NADH + H+
-
-
-
-
?
4-cyanobenzaldehyde + NAD+ + H2O
1.2.1.3 aldehyde dehydrogenase (NAD+)
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