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Literature summary for 1.14.14.139 extracted from

  • Pathak, P.; Li, T.; Chiang, J.Y.
    Retinoic acid related orphan receptor alpha regulates diurnal rhythm and fasting induction of sterol 12alpha-hydroxylase in bile acid synthesis (2013), J. Biol. Chem., 288, 37154-37165.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
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Mus musculus
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Synonyms

Synonyms Comment Organism
CYP8B1
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Mus musculus
sterol 12alpha-hydroxylase
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Mus musculus

Expression

Organism Comment Expression
Mus musculus CYP8B1 mRNA levels show a diurnal rhythm, decrease during the day and reaching the lowest levels 2 h into the dark cycle down
Mus musculus adenovirus-mediated gene transduction of retinoic acid-related orphan receptor alpha to mice strongly induces CYP8B1 expression (2.5fold) up