4.98.1.1: protoporphyrin ferrochelatase

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For detailed information about protoporphyrin ferrochelatase, go to the full flat file.

Word Map on EC 4.98.1.1

4.98.1.1

ataxia

friedreich

protoporphyria

erythropoietic

iron-sulfur

cardiomyopathy

fe-s

ferrous

ala

photosensitivity

aconitase

porphyria

expansions

delta-aminolevulinic

trinucleotide

triplet

5-aminolevulinic

erythroid

coproporphyrinogen

iron-binding

spinocerebellar

overload

photodynamic

hemin

iscu

desulfurase

ferritin

protoporphyrinogen

porphobilinogen

tetrapyrrole

uroporphyrinogen

diagnostics

biotechnology

griseofulvin

sideroblast

coproporphyria

iron-mediated

uroporphyrin

analysis

dysarthria

cluster-containing

phototoxicity

microcytic

porphyrinogenic

deferiprone

erythroid-specific

coinheritance

erythroleukemia

ala-pdt

medicine

idebenone

deuteroporphyrin

mesoporphyrin

delta-aminolaevulinate

Reaction

+ 2 H+ =

Synonyms

chelatase, ferro-, EC 4.99.1.1, FC1, FC2, FeC, FeCH, ferro-protoporphyrin chelatase, ferrochelatase, ferrochelatase 1, ferrochelatase I, ferrochelatase II, frataxin, HEM15, heme synthase, heme synthetase, hemH, HemH1, HemH2, hFC, host red cell ferrochelatase, iron chelatase, parasite genome-coded ferrochelatase, PfFC, PPIX ferrochelatase, protohaem ferrolyase, protoheme ferro-lyase, protoheme ferrolyase, protoheme lyase, protoporhyrin IX ferrochelatase, protoporphyrin (IX) ferrochelatase, protoporphyrin IX ferrochelatase, Shew_1140, Shew_2229, type II ferrochelatase

ECTree

4 Lyases

4.98 ATP-independent chelatases

4.98.1 Forming coordination complexes

4.98.1.1 protoporphyrin ferrochelatase

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Results	in table
12	Activating Compound
25492	AA Sequence
25	Application
1	CAS Registry Number
53	Cloned(Commentary)
11	Cofactor
19	Crystallization (Commentary)
3688	Disease/ Diagnostics
15	Expression
39	General Information
6	General Stability
102	Inhibitors
26	kcat/KM [mM/s]
7	Ki Value [mM]
197	KM Value [mM]
91	Localization
51	Metals/Ions
53	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
177	Organism
3	Oxidation Stability
8	Pathway
30	pH Optimum
4	pH Range
2	pI Value
3	Posttranslational Modification
130	Protein Variants
65	Purification (Commentary)
13	Reaction
1	Reaction Type
175	Reference
1	Renatured (Commentary)
72	Source Tissue
24	Specific Activity [micromol/min/mg]
11	Storage Stability
263	Substrates and Products (Substrate)
47	Subunits
117	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
5	Temperature Range [°C]
68	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 4.98.1.1 - protoporphyrin ferrochelatase

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protoheme + H+

protoporphyrin + Fe2+

2 entries

protoporphyrin + Fe2+

protoheme + 2 H+

3 entries

protoporphyrin + Fe2+

protoheme + H+

23 entries

protoporphyrin + Zn2+

Zn2+-protoporphyrin + H+

Arabidopsis thaliana

P42043

763563

protoporphyrin IX + Fe2+

11 entries

protoporphyrin IX + Fe2+

Fe-protoporphyrin IX + 2 H+

2 entries

protoporphyrin IX + Fe2+

Fe2+-protoporphyrin IX + 2 H+

Arabidopsis thaliana

763565

protoporphyrin IX + Fe2+

protoheme + 2 H+

Arabidopsis thaliana

762872

protoporphyrin IX + Fe2+

protoheme IX + 2 H+

12 entries