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4.98.1.1: protoporphyrin ferrochelatase

This is an abbreviated version!
For detailed information about protoporphyrin ferrochelatase, go to the full flat file.

Word Map on EC 4.98.1.1

Reaction

protoheme
+ 2 H+ =
protoporphyrin
 +
Fe2+

Synonyms

chelatase, ferro-, EC 4.99.1.1, FC1, FC2, FeC, FeCH, ferro-protoporphyrin chelatase, ferrochelatase, ferrochelatase 1, ferrochelatase I, ferrochelatase II, frataxin, HEM15, heme synthase, heme synthetase, hemH, HemH1, HemH2, hFC, host red cell ferrochelatase, iron chelatase, parasite genome-coded ferrochelatase, PfFC, PPIX ferrochelatase, protohaem ferrolyase, protoheme ferro-lyase, protoheme ferrolyase, protoheme lyase, protoporhyrin IX ferrochelatase, protoporphyrin (IX) ferrochelatase, protoporphyrin IX ferrochelatase, Shew_1140, Shew_2229, type II ferrochelatase

ECTree

     4 Lyases
         4.98 ATP-independent chelatases
             4.98.1 Forming coordination complexes
                4.98.1.1 protoporphyrin ferrochelatase

KI Value

KI Value on EC 4.98.1.1 - protoporphyrin ferrochelatase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0712 - 0.3376
deuteroporphyrin IX
0.0014 - 0.00251
N-Methylprotoporphyrin
0.007 - 2.4
Ni2+
additional information
additional information
-
Ki-values of porphyrin isomers that are not substrates are in the range of 0.013-0.07 mM, Ki-values of metalloporphyrin isomers that are not substrates are in the range of 0.002-0.013 mM, Ki-values for metal inhibitors are in the range of 0.01-0.05 mM
-