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4.98.1.1: protoporphyrin ferrochelatase

This is an abbreviated version!
For detailed information about protoporphyrin ferrochelatase, go to the full flat file.

Word Map on EC 4.98.1.1

Reaction

protoheme
+ 2 H+ =
protoporphyrin
+
Fe2+

Synonyms

chelatase, ferro-, EC 4.99.1.1, FC1, FC2, FeC, FeCH, ferro-protoporphyrin chelatase, ferrochelatase, ferrochelatase 1, ferrochelatase I, ferrochelatase II, frataxin, HEM15, heme synthase, heme synthetase, hemH, HemH1, HemH2, hFC, host red cell ferrochelatase, iron chelatase, parasite genome-coded ferrochelatase, PfFC, PPIX ferrochelatase, protohaem ferrolyase, protoheme ferro-lyase, protoheme ferrolyase, protoheme lyase, protoporhyrin IX ferrochelatase, protoporphyrin (IX) ferrochelatase, protoporphyrin IX ferrochelatase, Shew_1140, Shew_2229, type II ferrochelatase

ECTree

     4 Lyases
         4.98 ATP-independent chelatases
             4.98.1 Forming coordination complexes
                4.98.1.1 protoporphyrin ferrochelatase

KM Value

KM Value on EC 4.98.1.1 - protoporphyrin ferrochelatase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.056
2,4-bisacetal deuteroporphyrin
-
-
0.479
2,4-diacetyldeuteroporphyrin
-
-
0.052
2,4-disulfonic deuteroporphyrin
-
-
0.0052 - 0.56
Co2+
0.063 - 0.17
Cu2+
0.0213
deuteroporphyrin
-
-
0.0026 - 0.054
deuteroporphyrin IX
0.00048 - 0.166
Fe2+
0.055
hematoporphyrin
-
-
0.0057
hemin
-
pH 5.5, 45°C
0.004 - 0.1
mesoporphyrin
0.0047 - 0.0302
mesoporphyrin IX
0.012
myoglobin
-
at pH 6.5 and 30°C
-
0.02206 - 0.1037
Ni2+
0.0121 - 0.0246
porphyrin
0.002 - 0.05
protoporphyrin
0.00022 - 0.72
protoporphyrin IX
0.00017 - 0.06
Zn2+