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4.98.1.1: protoporphyrin ferrochelatase

This is an abbreviated version!
For detailed information about protoporphyrin ferrochelatase, go to the full flat file.

Word Map on EC 4.98.1.1

Reaction

protoheme
+ 2 H+ =
protoporphyrin
+
Fe2+

Synonyms

chelatase, ferro-, EC 4.99.1.1, FC1, FC2, FeC, FeCH, ferro-protoporphyrin chelatase, ferrochelatase, ferrochelatase 1, ferrochelatase I, ferrochelatase II, frataxin, HEM15, heme synthase, heme synthetase, hemH, HemH1, HemH2, hFC, host red cell ferrochelatase, iron chelatase, parasite genome-coded ferrochelatase, PfFC, PPIX ferrochelatase, protohaem ferrolyase, protoheme ferro-lyase, protoheme ferrolyase, protoheme lyase, protoporhyrin IX ferrochelatase, protoporphyrin (IX) ferrochelatase, protoporphyrin IX ferrochelatase, Shew_1140, Shew_2229, type II ferrochelatase

ECTree

     4 Lyases
         4.98 ATP-independent chelatases
             4.98.1 Forming coordination complexes
                4.98.1.1 protoporphyrin ferrochelatase

Molecular Weight

Molecular Weight on EC 4.98.1.1 - protoporphyrin ferrochelatase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
110000
-
1 * 110000, gel filtration in presence of sodium deoxycholate, SDS-PAGE
115000
-
1 * 115000, SDS-PAGE, gel filtration in presence of sodium deoxycholate
160000
-
wild-type enzyme, gel filtration
200000
-
gel filtration
240000
-
gel filtration
250000 - 320000
-
irradiation experiments
315000
-
protoporphyrin ferrochelatase PpfC, gel filtration
32500
monomer, truncated protein, SDS-PAGE
33000
-
x * 33000, SDS-PAGE
35000
38000
39000
-
x * 39000, SDS-PAGE
40000
41200
monomer, calculated from amino acid sequence
42000
42700
-
2 * 42700, SDS-PAGE
43000
x * 43000, SDS-PAGE
45000
-
deltaH324 mutant, gel filtration
46000
-
full-length enzyme, immunoprecipitation
46100
monomer, predicted from amino acid sequence
47000
50000
-
minimum molecular weight, gel filtration in presence of Brig 35 and dithiothreitol
512000
-
complex between protoporphyrinogen dehydrogenase PgdH1 and protoporphyrin ferrochelatase PpfC, gel filtration
54430
monomer, precursor protein, predicted from amino acid sequence
60000
-
wild-type enzyme, gel filtration
63000
-
1 * 63000, SDS-PAGE
80000
84000
86000
-
gel filtration
90000
mutant C406S, dimer, dynamic light scattering
additional information