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Literature summary for 4.98.1.1 extracted from

  • Lange, H.; Muhlenhoff, U.; Denzel, M.; Kispal, G.; Lill, R.
    The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase (2004), J. Biol. Chem., 279, 29101-29108.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information unknown mitochondrial compound with a molecular mass greater than 10 kD, reversible inhibition Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Saccharomyces cerevisiae 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoporphyrin + Fe2+ Saccharomyces cerevisiae
-
protoheme + 2 H+
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P16622
-
-

Purification (Commentary)

Purification (Comment) Organism
immunopurification from mitochondrial extracts Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deuteroporphyrin + Fe2+
-
Saccharomyces cerevisiae deuteroheme + 2 H+
-
?
protoporphyrin + Fe2+
-
Saccharomyces cerevisiae protoheme + 2 H+
-
?
protoporphyrin IX + Zn2+
-
Saccharomyces cerevisiae Zn-protoporphyrin + H+
-
?

Synonyms

Synonyms Comment Organism
ferrochelatase
-
Saccharomyces cerevisiae