Cloned (Comment) | Organism |
---|---|
expressed in a Saccharomyces cerevisiae hem15-deficient strain | Cryptococcus neoformans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Neurospora crassa | 5739 | - |
mitochondrion | - |
Phycomyces blakesleeanus | 5739 | - |
mitochondrion | - |
Rhizopus arrhizus | 5739 | - |
mitochondrion | - |
Candida albicans | 5739 | - |
mitochondrion | - |
Cryptococcus neoformans | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoporphyrin + Fe2+ | Neurospora crassa | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Phycomyces blakesleeanus | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Rhizopus arrhizus | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Candida albicans | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Cryptococcus neoformans | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Phycomyces blakesleeanus NRRL1555 | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Rhizopus arrhizus RA 99-880 | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Neurospora crassa FGSC 4200 | - |
protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | Cryptococcus neoformans JEC21 | - |
protoheme + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Cryptococcus neoformans | Q5KFH8 | - |
- |
Cryptococcus neoformans JEC21 | Q5KFH8 | - |
- |
Neurospora crassa | - |
- |
- |
Neurospora crassa FGSC 4200 | - |
- |
- |
Phycomyces blakesleeanus | - |
- |
- |
Phycomyces blakesleeanus NRRL1555 | - |
- |
- |
Rhizopus arrhizus | - |
- |
- |
Rhizopus arrhizus RA 99-880 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoporphyrin + Fe2+ | - |
Neurospora crassa | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Phycomyces blakesleeanus | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Rhizopus arrhizus | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Candida albicans | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Cryptococcus neoformans | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Phycomyces blakesleeanus NRRL1555 | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Rhizopus arrhizus RA 99-880 | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Neurospora crassa FGSC 4200 | protoheme + H+ | - |
? | |
protoporphyrin + Fe2+ | - |
Cryptococcus neoformans JEC21 | protoheme + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HEM15 | - |
Neurospora crassa |
HEM15 | - |
Phycomyces blakesleeanus |
HEM15 | - |
Rhizopus arrhizus |
HEM15 | - |
Candida albicans |
HEM15 | - |
Cryptococcus neoformans |
Organism | Comment | Expression |
---|---|---|
Neurospora crassa | ferrochelatase is light-regulated in a white collar-dependent fashion, ferrochelatase transcript levels are higher after 1 h light exposure when compared with those of the strains grown in the dark | up |
Phycomyces blakesleeanus | ferrochelatase is light-regulated in a white collar-dependent fashion, ferrochelatase transcript levels are higher after 1 h light exposure when compared with those of the strains grown in the dark | up |
Rhizopus arrhizus | ferrochelatase is light-regulated in a white collar-dependent fashion, ferrochelatase transcript levels are higher after 1 h light exposure when compared with those of the strains grown in the dark | up |
Candida albicans | ferrochelatase is light-regulated in a white collar-dependent fashion, ferrochelatase transcript levels are higher after 1 h light exposure when compared with those of the strains grown in the dark | up |
Cryptococcus neoformans | ferrochelatase is light-regulated in a white collar-dependent fashion, ferrochelatase transcript levels are higher after 1 h light exposure when compared with those of the strains grown in the dark | up |
General Information | Comment | Organism |
---|---|---|
physiological function | HEM15 encodes a ferrochelatase that catalyses the final step in heme biosynthesis from highly photoreactive porphyrins. The enzyme is essential for viability | Neurospora crassa |
physiological function | HEM15 encodes a ferrochelatase that catalyses the final step in heme biosynthesis from highly photoreactive porphyrins. The enzyme is essential for viability | Phycomyces blakesleeanus |
physiological function | HEM15 encodes a ferrochelatase that catalyses the final step in heme biosynthesis from highly photoreactive porphyrins. The enzyme is essential for viability | Rhizopus arrhizus |
physiological function | HEM15 encodes a ferrochelatase that catalyses the final step in heme biosynthesis from highly photoreactive porphyrins. The enzyme is essential for viability | Candida albicans |
physiological function | HEM15 encodes a ferrochelatase that catalyses the final step in heme biosynthesis from highly photoreactive porphyrins. The enzyme is essential for viability | Cryptococcus neoformans |