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3.4.11.10: bacterial leucyl aminopeptidase

This is an abbreviated version!
For detailed information about bacterial leucyl aminopeptidase, go to the full flat file.

Word Map on EC 3.4.11.10

Reaction

release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids =

Synonyms

AAP, Aeromonas proteolytica aminopeptidase, Aminopeptidase, aminopeptidase A, aminopeptidase A (bacteria), aminopeptidase Ap1, aminopeptidase II, AP-II, API, APII, AVP, bacterial leucine aminopeptidase, bacterial M17 aminopeptidase, BSAP, Bsu aminopeptidase, BsuAP, CGase, cysteinylglycinase, double-zinc aminopeptidase, extracellular aminopeptidase, FgLAP, HpM17AP, LAP, LAPII, leucine aminopeptidase, leucine aminopeptidase II, leucine APN, Leucyl aminopeptidase, M17 aminopeptidase, M17 metallo-aminopeptidase, More, MtLAP, PepA, Peptidase A, pepZ, PhpA, ribosomal-bound aminopeptidase, rLAP55, Rv2213, SSAP, TAP, TH-2, thermophilic aminopeptidase, thermostable leucine aminopeptidase, Vibrio aminopeptidase, VpAP, ywaD

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.10 bacterial leucyl aminopeptidase

Reference

Reference on EC 3.4.11.10 - bacterial leucyl aminopeptidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Baker, J.O.; Prescott, J.M.
A transition-state-analog inhibitor influences zinc-binding by Aeromonas aminopeptidase
Biochem. Biophys. Res. Commun.
130
1154-1160
1985
Vibrio proteolyticus
Manually annotated by BRENDA team
Wilkes, S.H.; Prescott, J.M.
The slow, tight binding of bestatin and amastatin to aminopeptidases
J. Biol. Chem.
260
13154-13162
1985
Vibrio proteolyticus
Manually annotated by BRENDA team
Prescott, J.M.; Wagner, F.W.; Holmquist, B.; Vallee, B.L.
Spectral and kinetic studies of metal-substituted Aeromonas aminopeptidase: nonidentical, interacting metal-binding sites
Biochemistry
24
5350-5356
1985
Vibrio proteolyticus
Manually annotated by BRENDA team
Wilkes, S.H.; Prescott, J.M.
Stereospecificity of amino acid hydroxamate inhibition of aminopeptidases
J. Biol. Chem.
258
13517-13521
1983
Vibrio proteolyticus
Manually annotated by BRENDA team
Prescott, J.M.; Wagner, F.W.; Holmquist, B.; Vallee, B.L.
One hundred fold increased activity of Aeromonas aminopeptidase by sequential substitutions with Ni(II) or Cu(II) followed by zinc
Biochem. Biophys. Res. Commun.
114
646-652
1983
Vibrio proteolyticus
Manually annotated by BRENDA team
Baker, J.O.; Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Hydroxamates and aliphatic boronic acids: marker inhibitors for aminopeptidase
Biochemistry
22
2098-2103
1983
Vibrio proteolyticus
Manually annotated by BRENDA team
Prescott, J.M.; Wilkes, S.H.
Aeromonas aminopeptidase
Methods Enzymol.
45
530-543
1976
Vibrio proteolyticus
Manually annotated by BRENDA team
Kettner, C.; Glover, G.I.; Prescott, J.M.
Kinetics of inhibition of Aeromonas aminopeptidase by leucine methyl ketone derivatives
Arch. Biochem. Biophys.
165
739-743
1974
Vibrio proteolyticus
Manually annotated by BRENDA team
Kettner, C.; Rodriguez-Absi, J.; Glover, G.I.; Prescott, J.M.
The purification of Aeromonas aminopeptidase by affinity chromatography
Arch. Biochem. Biophys.
162
56-63
1974
Vibrio proteolyticus
Manually annotated by BRENDA team
Wagner, F.W.; Wilkes, S.H.; Prescott, J.M.
Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides
J. Biol. Chem.
247
1208-1210
1972
Vibrio proteolyticus
Manually annotated by BRENDA team
Prescott, J.M.; Wilkes, S.H.; Wagner, F.W.; Wilson, K.J.
Aeromonas aminopeptidase. Improved isolation and some physical properties
J. Biol. Chem.
246
1756-1764
1971
Vibrio proteolyticus
Manually annotated by BRENDA team
Prescott, J.M.; Wilkes, S.H.
Aeromonas aminopeptidase: purification and some general properties
Arch. Biochem. Biophys.
117
328-336
1966
Vibrio proteolyticus
Manually annotated by BRENDA team
Maekinen, K.K.; Maekinen, P.L.; Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Chemical modification of Aeromonas aminopeptidase. Evidence for the involvement of tyrosyl and carboxyl groups in the activity of the enzyme
Eur. J. Biochem.
128
257-265
1982
Vibrio proteolyticus
Manually annotated by BRENDA team
Maekinen, K.K.; Maekinen, P.L.; Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Photochemical inactivation of Aeromonas aminopeptidase by 2,3-butanedione
J. Biol. Chem.
257
1765-1772
1982
Vibrio proteolyticus
Manually annotated by BRENDA team
Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides
Eur. J. Biochem.
34
459-466
1973
Vibrio proteolyticus
Manually annotated by BRENDA team
Schalk, C.; Remy, J.M.; Chevrier, B.; Moras, D.; Tarnus, C.
Rapid purification of the Aeromonas proteolytica aminopeptidase: crystallization and preliminary X-ray data
Arch. Biochem. Biophys.
294
91-97
1992
Vibrio proteolyticus
Manually annotated by BRENDA team
Bennett, B.; Holz, R.C.
Spectroscopically distinct cobalt(II) sites in heterodimetallic forms of the aminopeptidase from Aeromonas proteolytica: characterization of substrate binding
Biochemistry
36
9837-9846
1997
Vibrio proteolyticus
Manually annotated by BRENDA team
Chevrier, B.; D'Orchymont, H.; Schalk, C.; Moras, D.
The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit
Eur. J. Biochem.
237
393-398
1996
Vibrio proteolyticus
Manually annotated by BRENDA team
De Paola, C.C.; Bennett, B.; Holz, R.C.; Ringe, D.; Petsko, G.A.
1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development
Biochemistry
38
9048-9053
1999
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Ustynyuk, L.; Bennett, B.; Edwards, T.; Holz, R.C.
Inhibition of the aminopeptidase from Aeromonas proteolytica by aliphatic alcohols. Characterization of the hydrophobic substrate recognition site
Biochemistry
38
11433-11439
1999
Vibrio proteolyticus
Manually annotated by BRENDA team
Huntington, K.M.; Bienvenue, D.L.; Wei, Y.; Bennett, B.; Holz, R.C.; Pei, D.
Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization
Biochemistry
38
15587-15596
1999
Vibrio proteolyticus
Manually annotated by BRENDA team
Izawa, N.; Ishikawa, S.; Tanokura, T.; Ohta, K.; Hayashi, K.
Purification and characterization of Aeromonas caviae aminopeptidase possessing dibittering activity.
J. Agric. Food Chem.
45
4897-4902
1997
Aeromonas caviae
Manually annotated by BRENDA team
Dick, A.J.; Matheson, A.T.; Wang, J.H.
A ribosomal-bound aminopeptidase in Escherichia coli B: purification and properties
Can. J. Biochem.
48
1181-1188
1970
Escherichia coli
Manually annotated by BRENDA team
Stamper, C.; Bennett, B.; Edwards, T.; Holz, R.C.; Ringe, D.; Petsko, G.
Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis
Biochemistry
40
7035-7046
2001
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Bienvenue, D.L.; Gilner, D.; Holz, R.C.
Hydrolysis of thionopeptides by the aminopeptidase from Aeromonas proteolytica: insight into substrate binding
Biochemistry
41
3712-3719
2002
Vibrio proteolyticus
Manually annotated by BRENDA team
Bienvenue, D.L.; Mathew, R.S.; Ringe, D.; Holz, R.C.
The aminopeptidase from Aeromonas proteolytica can function as an esterase
J. Biol. Inorg. Chem.
7
129-135
2002
Vibrio proteolyticus
Manually annotated by BRENDA team
Desmarais, W.T.; Bienvenue, D.L.; Bzymek, K.P.; Holz, R.C.; Petsko, G.A.; Ringe, D.
The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition
Structure
10
1063-1072
2002
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Reiland, V.; Fundoiano-Hershcovitz, Y.; Golan, G.; Gilboa, R.; Shoham, Y.; Shoham, G.
Preliminary crystallographic characterization of BSAP, an extracellular aminopeptidase from Bacillus subtilis
Acta Crystallogr. Sect. D
60
2371-2376
2004
Bacillus subtilis
Manually annotated by BRENDA team
Jankiewicz, U.; Bielawski, W.
The properties and functions of bacterial aminopeptidases
Acta Microbiol. Pol.
52
217-231
2003
Vibrio proteolyticus, Brevibacterium linens, Escherichia coli, Lactococcus sp., Pseudomonas aeruginosa, Pseudomonas putida, Salmonella enterica subsp. enterica serovar Typhimurium, Mycoplasma salivarium, Brevibacterium linens SR3
Manually annotated by BRENDA team
Chi, M.C.; Chou, W.M.; Wang, C.H.; Chen, W.; Hsu, W.H.; Lin, L.L.
Generating oxidation-resistant variants of Bacillus kaustophilus leucine aminopeptidase by substitution of the critical methionine residues with leucine
Antonie van Leeuwenhoek
86
355-362
2004
Geobacillus kaustophilus
Manually annotated by BRENDA team
Hwang, G.Y.; Kuo, L.Y.; Tsai, M.R.; Yang, S.L.; Lin, L.L.
Histidines 345 and 378 of Bacillus stearothermophilus leucine aminopeptidase II are essential for the catalytic activity of the enzyme
Antonie van Leeuwenhoek
87
355-359
2005
Geobacillus stearothermophilus (P24828), Geobacillus stearothermophilus
Manually annotated by BRENDA team
Schuerer, G.; Lanig, H.; Clark, T.
Aeromonas proteolytica aminopeptidase: an investigation of the mode of action using a quantum mechanical/molecular mechanical approach
Biochemistry
43
5414-5427
2004
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Bzymek, K.P.; Moulin, A.; Swierczek, S.I.; Ringe, D.; Petsko, G.A.; Bennett, B.; Holz, R.C.
Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica
Biochemistry
44
12030-12040
2005
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Wan, X.; Branton, S.L.; Hanson, L.A.; Pharr, G.T.
Identification and initial characterization of a putative Mycoplasma gallinarum leucine aminopeptidase gene
Curr. Microbiol.
48
32-38
2004
Mycoplasmopsis gallinarum (Q8RLK7), Mycoplasmopsis gallinarum
Manually annotated by BRENDA team
Bennett, B.
EPR of Co(II) as a structural and mechanistic probe of metalloprotein active sites: characterisation of an aminopeptidase
Curr. Top. Biophys.
26
49-57
2002
Vibrio proteolyticus
-
Manually annotated by BRENDA team
Lin, L.L.; Hsu, W.H.; Wu, C.P.; Chi, M.C.; Chou, W.M.; Hu, H.Y.
A thermostable leucine aminopeptidase from Bacillus kaustophilus CCRC 11223
Extremophiles
8
79-87
2004
Geobacillus kaustophilus, Geobacillus kaustophilus CCRC 11223
Manually annotated by BRENDA team
Fundoiano-Hershcovitz, Y.; Rabinovitch, L.; Shulami, S.; Reiland, V.; Shoham, G.; Shoham, Y.
The ywad gene from Bacillus subtilis encodes a double-zinc aminopeptidase
FEMS Microbiol. Lett.
243
157-163
2005
Bacillus subtilis (P25152)
Manually annotated by BRENDA team
Straeter, N.; Lipscomb, W.N.
Leucine aminopeptidase
Handbook of Metalloproteins (Messerschmidt, A. ; Huber, R. ; Wieghardt, K. ; Palos, T. , eds. )
3
199-207
2004
Escherichia coli
-
Manually annotated by BRENDA team
Colloms, S.D.
Leucyl aminopeptidase PepA
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds)
1
905-910
2004
Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica subsp. enterica serovar Typhimurium
-
Manually annotated by BRENDA team
Chevrier, B.; D'Orchymont, H.
Vibrio aminopeptidase
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds)
1
963-965
2004
Vibrio proteolyticus
-
Manually annotated by BRENDA team
Bertin, P.B.; Lozzi, S.P.; Howell, J.K.; Restrepo-Cadavid, G.; Neves, D.; Teixeira, A.R.L.; De Sousa, M.V.; Norris, S.J.; Santana, J.M.
The thermophilic, homohexameric aminopeptidase of Borrelia burgdorferi is a member of the M29 family of metallopeptidases
Infect. Immun.
73
2253-2261
2005
Borreliella burgdorferi (O51096)
Manually annotated by BRENDA team
Bzymek, K.P.; Swierczek, S.I.; Bennett, B.; Holz, R.C.
Spectroscopic and thermodynamic characterization of the E151D and E151A altered leucine aminopeptidases from Aeromonas proteolytica
Inorg. Chem.
44
8574-8580
2005
Vibrio proteolyticus
Manually annotated by BRENDA team
Fernandez, J.; Mohedano, A.F.; Gaya, P.; Medina, M.; Nunez, M.
Purification and properties of two intracellular aminopeptidases produced by Brevibacterium linens SR3
Int. Dairy J.
10
241-248
2000
Brevibacterium linens, Brevibacterium linens SR3
Manually annotated by BRENDA team
Deejing, S.; Yoshimune, K.; Lumyong, S.; Moriguchi, M.
Purification and characterization of hyperthermotolerant leucine aminopeptidase from Geobacillus thermoleovorans 47b
J. Ind. Microbiol. Biotechnol.
32
269-276
2005
Geobacillus thermoleovorans, Geobacillus thermoleovorans 47b
Manually annotated by BRENDA team
Bienvenue, D.L.; Bennett, B.; Holz, R.C.
Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinethiol: kinetic and spectroscopic characterization of a slow, tight-binding inhibitor-enzyme complex
J. Inorg. Biochem.
78
43-54
2000
Vibrio proteolyticus
Manually annotated by BRENDA team
Dong, L.; Cheng, N.; Wang, M.W.; Zhang, J.; Shu, C.; Zhu, D.X.
The leucyl aminopeptidase from Helicobacter pylori is an allosteric enzyme
Microbiology
151
2017-2023
2005
Helicobacter pylori
Manually annotated by BRENDA team
Bzymek, K.P.; D'Souza, V.M.; Chen, G.; Campbell, H.; Mitchell, A.; Holz, R.C.
Function of the signal peptide and N- and C-terminal propeptides in the leucine aminopeptidase from Aeromonas proteolytica
Protein Expr. Purif.
37
294-305
2004
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Hua, Y.W.; Chi, M.C.; Lo, H.F.; Kuo, L.Y.; Ku, K.L.; Lin, L.L.
Adsorption-elution purification of chimeric Bacillus stearothermophilus leucine aminopeptidase II with raw-starch-binding activity
World J. Microbiol. Biotechnol.
21
689-694
2005
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Arima, J.; Uesugi, Y.; Iwabuchi, M.; Hatanaka, T.
Change in substrate preference of Streptomyces aminopeptidase through modification of the environment around the substrate binding site
Appl. Environ. Microbiol.
72
7962-7967
2006
Streptomyces septatus
Manually annotated by BRENDA team
Kumar, A.; Periyannan, G.R.; Narayanan, B.; Kittell, A.W.; Kim, J.J.; Bennett, B.
Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus
Biochem. J.
403
527-536
2007
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Albrecht, S.; Defoin, A.; Salomon, E.; Tarnus, C.; Wetterholm, A.; Haeggstroem, J.Z.
Synthesis and structure activity relationships of novel non-peptidic metallo-aminopeptidase inhibitors
Bioorg. Med. Chem.
14
7241-7257
2006
Vibrio proteolyticus
Manually annotated by BRENDA team
Chen, S.; Marino, T.; Fang, W.; Russo, N.; Himo, F.
Peptide hydrolysis by the binuclear zinc enzyme aminopeptidase from Aeromonas proteolytica: A density functional theory study
J. Phys. Chem. B
112
2494-2500
2008
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Ataie, N.J.; Hoang, Q.Q.; Zahniser, M.P.; Tu, Y.; Milne, A.; Petsko, G.A.; Ringe, D.
Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus
Biochemistry
47
7673-7683
2008
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Chu, L.; Lai, Y.; Xu, X.; Eddy, S.; Yang, S.; Song, L.; Kolodrubetz, D.
A 52-kDa leucyl aminopeptidase from Treponema denticola is a cysteinylglycinase that mediates the second step of glutathione metabolism
J. Biol. Chem.
283
19351-19358
2008
Treponema denticola
Manually annotated by BRENDA team
Sarnovsky, R.; Rea, J.; Makowski, M.; Hertle, R.; Kelly, C.; Antignani, A.; Pastrana, D.V.; Fitzgerald, D.J.
Proteolytic cleavage of a C-terminal prosequence, leading to autoprocessing at the N terminus, activates leucine aminopeptidase from Pseudomonas aeruginosa
J. Biol. Chem.
284
10243-10253
2009
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Nguyen, K.T.; Pei, D.
High-throughput screening of peptide deformylase inhibitors
Methods Mol. Med.
142
117-130
2008
Aeromonas sp.
Manually annotated by BRENDA team
Acosta, D.; Cancela, M.; Piacenza, L.; Roche, L.; Carmona, C.; Tort, J.F.
Fasciola hepatica leucine aminopeptidase, a promising candidate for vaccination against ruminant fasciolosis
Mol. Biochem. Parasitol.
158
52-64
2008
Fasciola hepatica
Manually annotated by BRENDA team
Hartley, M.; Bennett, B.
Heterologous expression and purification of Vibrio proteolyticus (Aeromonas proteolytica) aminopeptidase: a rapid protocol
Protein Expr. Purif.
66
91-101
2009
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Lin, L.L.; Chen, Y.P.; Yang, J.C.; Hua, Y.W.; Wang, W.C.; Kuo, L.Y.
Significance of the conserved Tyr352 and Asp380 residues in the catalytic activity of Bacillus stearothermophilus aminopeptidase II as evaluated by site-directed mutagenesis
Protein J.
27
215-222
2008
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Huynh, K.H.; Natarajan, S.; Choi, J.; Song, N.H.; Kim, J.G.; Lee, B.M.; Ahn, Y.J.; Kang, L.W.
Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of leucine aminopeptidase (LAP) from the pepA gene of Xanthomonas oryzae pv. oryzae
Acta Crystallogr. Sect. F
65
952-955
2009
Xanthomonas oryzae pv. oryzae KACC 10331
Manually annotated by BRENDA team
Bhosale, M.; Pande, S.; Kumar, A.; Kairamkonda, S.; Nandi, D.
Characterization of two M17 family members in Escherichia coli, Peptidase A and Peptidase B
Biochem. Biophys. Res. Commun.
395
76-81
2010
Escherichia coli
Manually annotated by BRENDA team
Huang, C.L.; Cheng, W.C.; Yang, J.C.; Chi, M.C.; Chen, J.H.; Lin, H.P.; Lin, L.L.
Preparation of carboxylated magnetic particles for the efficient immobilization of C-terminally lysine-tagged Bacillus stearothermophilus aminopeptidase II
J. Ind. Microbiol. Biotechnol.
37
717-735
2010
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Kale, A.; Pijning, T.; Sonke, T.; Dijkstra, B.W.; Thunnissen, A.M.
Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity
J. Mol. Biol.
398
703-714
2010
Pseudomonas putida (O86436)
Manually annotated by BRENDA team
Frey, S.T.; Guilmet, S.L.; Egan, R.G.; Bennett, A.; Soltau, S.R.; Holz, R.C.
Immobilization of the aminopeptidase from Aeromonas proteolytica on Mg2+/Al3+ layered double hydroxide particles
ACS Appl. Mater. Interfaces
2
2828-2832
2010
Vibrio proteolyticus
Manually annotated by BRENDA team
Albrecht, S.; Al-Lakkis-Wehbe, M.; Orsini, A.; Defoin, A.; Pale, P.; Salomon, E.; Tarnus, C.; Weibel, J.
Amino-benzosuberone: A novel warhead for selective inhibition of human aminopeptidase-N/CD13
Bioorg. Med. Chem.
19
1434-1449
2011
Vibrio proteolyticus
Manually annotated by BRENDA team
Perez-Sanchez, G.; Leal-Guadarrama, L.; Trelles, I.; Perez, N.; Medina-Rivero, E.
High-level production of a recombinant Vibrio proteolyticus leucine aminopeptidase and its use for N-terminal methionine excision from interferon alpha-2b
Process Biochem.
46
1825-1830
2011
Vibrio proteolyticus (Q01693)
-
Manually annotated by BRENDA team
Modak, J.K.; Roujeinikova, A.
Cloning, purification and preliminary crystallographic analysis of the Helicobacter pylori leucyl aminopeptidase-bestatin complex
Acta Crystallogr. Sect. F
69
1011-1014
2013
Helicobacter pylori
Manually annotated by BRENDA team
Changklungmoa, N.; Chaithirayanon, K.; Kueakhai, P.; Meemon, K.; Riengrojpitak, S.; Sobhon, P.
Molecular cloning and characterization of leucine aminopeptidase from Fasciola gigantica
Exp. Parasitol.
131
283-291
2012
Fasciola gigantica
Manually annotated by BRENDA team
Xi, H.; Tian, Y.; Zhou, N.; Zhou, Z.; Shen, W.
Characterization of an N-glycosylated Bacillus subtilis leucine aminopeptidase expressed in Pichia pastoris
J. Basic Microbiol.
55
236-246
2015
Bacillus subtilis
Manually annotated by BRENDA team
Hanaya, K.; Suetsugu, M.; Saijo, S.; Yamato, I.; Aoki, S.
Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn2+ fluorophores, kinetic, and X-ray crystallographic study
J. Biol. Inorg. Chem.
17
517-529
2012
Vibrio proteolyticus
Manually annotated by BRENDA team
Carroll, R.K.; Robison, T.M.; Rivera, F.E.; Davenport, J.E.; Jonsson, I.M.; Florczyk, D.; Tarkowski, A.; Potempa, J.; Koziel, J.; Shaw, L.N.
Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus
Microbes Infect.
14
989-999
2012
Staphylococcus aureus
Manually annotated by BRENDA team
Changklungmoa, N.; Kueakhai, P.; Riengrojpitak, S.; Chaithirayanon, K.; Chaichanasak, P.; Preyavichyapugdee, N.; Chantree, P.; Sansri, V.; Itagaki, T.; Sobhon, P.
Immunization with recombinant leucine aminopeptidase showed protection against Fasciola gigantica in mice
Parasitol. Res.
112
3653-3659
2013
Fasciola gigantica
Manually annotated by BRENDA team
Kishor, N.; Guptasarma, P.
Direct N-terminal sequencing of polypeptides using a thermostable bacterial aminopeptidase and MALDI-TOF mass spectrometry
Anal. Biochem.
488
6-8
2015
Bacillus subtilis (P25152), Bacillus subtilis 168 (P25152)
Manually annotated by BRENDA team
Modak, J.K.; Rut, W.; Wijeyewickrema, L.C.; Pike, R.N.; Drag, M.; Roujeinikova, A.
Structural basis for substrate specificity of Helicobacter pylori M17 aminopeptidase
Biochimie
121
60-71
2016
Helicobacter pylori (O25294), Helicobacter pylori, Helicobacter pylori ATCC 700392 (O25294), Helicobacter pylori 26695 (O25294)
Manually annotated by BRENDA team
Correa, A.F
; Bastos, I.M.D.; Neves, D.; Kipnis, A.; Junqueira-Kipnis, A.P.; de Santana, J.M. The activity of a hexameric M17 metallo-aminopeptidase is associated with survival of Mycobacterium tuberculosis
Front. Microbiol.
8
504-516
2017
Mycobacterium tuberculosis (P9WHT3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WHT3)
Manually annotated by BRENDA team
Hernandez-Moreno, A.V.; Villasenor, F.; Medina-Rivero, E.; Perez, N.O.; Flores-Ortiz, L.F.; Saab-Rincon, G.; Luna-Barcenas, G.
Kinetics and conformational stability studies of recombinant leucine aminopeptidase
Int. J. Biol. Macromol.
64
306-312
2014
Vibrio proteolyticus (Q01693)
Manually annotated by BRENDA team
Xi, H.; Tian, Y.; Zhou, N.; Zhou, Z.; Shen, W.
Characterization of an N-glycosylated Bacillus subtilis leucine aminopeptidase expressed in Pichia pastoris
J. Basic Microbiol.
55
236-246
2015
Bacillus subtilis (O32106), Bacillus subtilis Zj016 (O32106)
Manually annotated by BRENDA team