3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase
This is an abbreviated version!
For detailed information about 2',3'-cyclic-nucleotide 3'-phosphodiesterase, go to the full flat file.
Word Map on EC 3.1.4.37
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3.1.4.37
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myelin
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oligodendrocyte
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glial
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mbp
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matter
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astrocyte
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nerve
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demyelination
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cord
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fibrillary
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sclerosis
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myelin-associated
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sheath
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proteolipid
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cerebral
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oligodendroglial
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corpus
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schwann
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callosum
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sulfatide
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microglia
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nestin
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galactocerebroside
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sciatic
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3\'-cyclic
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myelin-specific
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myelin-related
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hypomyelination
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5'-nucleotidase
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myelinogenesis
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neurofilament
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galactolipids
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medicine
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diagnostics
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luxol
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ensheathing
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cuprizone
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quaking
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cerebroside
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paranodal
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jimpy
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cuprizone-induced
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shiverer
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myelin-like
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myelin-forming
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oligodendrocyte-specific
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analysis
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oligodendrogenesis
- 3.1.4.37
- myelin
- oligodendrocyte
- glial
- mbp
- matter
- astrocyte
- nerve
- demyelination
- cord
-
fibrillary
- sclerosis
-
myelin-associated
- sheath
-
proteolipid
- cerebral
- oligodendroglial
-
corpus
-
schwann
- callosum
- sulfatide
- microglia
- nestin
- galactocerebroside
-
sciatic
-
3\'-cyclic
-
myelin-specific
-
myelin-related
-
hypomyelination
- 5'-nucleotidase
-
myelinogenesis
- neurofilament
- galactolipids
- medicine
- diagnostics
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luxol
-
ensheathing
- cuprizone
-
quaking
- cerebroside
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paranodal
-
jimpy
-
cuprizone-induced
-
shiverer
-
myelin-like
-
myelin-forming
-
oligodendrocyte-specific
- analysis
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oligodendrogenesis
Reaction
Synonyms
2',3'-cyclic AMP phosphodiesterase, 2',3'-cyclic nucleoside monophosphate phosphodiesterase, 2',3'-cyclic nucleotide 3'-phosphodiesterase, 2',3'-cyclic nucleotide 3'-phosphohydrolase, 2',3'-cyclic nucleotide phosphodiesterase, 2',3'-cyclic nucleotide phosphohydrolase, 2',3'-cyclic nucleotide-3'-phosphodiesterase, 2',3'-cyclic nucleotide-3'-phosphohydrolase, 2',3'-cyclic phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I, 2':3'-CNMP-3'-ase, 2':3'-cyclic nucleotide 3'-phosphodiesterase, 3DMA, CNP, CNP1, CNP2, CNPase, CNPase I, cyclic 2',3'-nucleotide 3'-phosphodiesterase, cyclic 2',3'-nucleotide phosphodiesterase, cyclic-CMP phosphodiesterase, DGC2, nucleoside-2':3'-cyclic-phosphate 2'-nucleotidohydrolase, PaAcpH, phosphodiesterase, cyclic 2',3'-nucleotide 3'-, PNKP, RocR, YtqI, YybT
ECTree
3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesteraseAdvanced search results
results (
results (Source Tissue
Source Tissue on EC 3.1.4.37 - 2',3'-cyclic-nucleotide 3'-phosphodiesterase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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presence of enzyme immunoreactive material at birth, progressive reduction with age with complete loss at postnatal day 18
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ATCC CRL 8305, thyroid cells, CNP is firmly associated with FRTL-5 cells
quantitative isozymes expression analysis in hepatoma cell lines
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peripheral nerve sheath tumors, immunohistochemic and histochemic analysis of 63 tumors from 44 cattle: 35 schwannomas, 9 neurofibromas, 14 hybrid (neurofibroma-schwannoma) tumors, and 5 malignant peripheral nerve sheath tumors
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peripheral nerve sheath tumors, immunohistochemic and histochemic analysis of 63 tumors from 44 cattle: 35 schwannomas, 9 neurofibromas, 14 hybrid (neurofibroma-schwannoma) tumors, and 5 malignant peripheral nerve sheath tumors
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presence of enzyme immunoreactive material at birth, progressive reduction with age with complete loss at postnatal day 18
additional information
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135380, 135381, 135399, 135401, 135404, 135407, 135418, 135419, 135422, 729185, 729954, 730238, 730475, 751698
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CNPase expression pattern of brain tissues in hypothyroid and control rats from post-natal days 5 to 90, hypothyroidism impairs transiently the CNPase gene expression, effect on oligodendrocyte differentiation and myelination
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subventricular zone rostral extension, CNPase expression pattern during development from postnatal day 3 to 60
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there is little CNP2 in the forebrain postsynaptic density fraction, CNP1 is the major isoform in the neural and non-neural rat tissues, with the exception of myelinating cells in the adult brain, in which both isoforms are highly expressed, CNP2 is barely detectable in embryonic brain
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cerebellar postsynaptic density fraction, both isoforms CNP1 and CNP2 are expressed in cerian populations of cerebellar cells, in oligodendrocytes, Purkinje cells and unidentified PSD95-positive cells, not in granule cells
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with age, CNP accumulates throughout brain white matter accompanied by proteolytic fragments of CNP. Equal increase in both isoforms CNP1 and CNP2
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presence of enzyme immunoreactive material at birth, progressive reduction with age with complete loss at postnatal day 18
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oligodendrocyte-enriched cultures of neonatal rat brain glial cells, CNP2
the enzyme is expressed in liver tissues with hepatitis B virus infection
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with age, CNP accumulates in myelin accompanied by proteolytic fragments of CNP. Equal increase in both isoforms CNP1 and CNP2
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the enzyme is most abundant protein in non-compact myelin and the third-most abundant protein overall in CNS myellin
a highly abundant membrane-associated enzyme in the myelin sheath of the vertebrate nervous system
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the enzyme is one of the most abundant proteins in CNS myelin
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the enzyme is a quantitatively major enzyme in myelin, where it localizes to the non-compact regions and is bound to the membrane surface
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the enzyme is one of the most abundant proteins in CNS myelin
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developing, detailed CNPase expression pattern during development from postnatal day 3 to 60, expression follows a general caudorostral gradient, with the exception of the glomerular layer
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olfactory ensheathing cells, the nonmyelinating glial cells of the olfactory nerves and bulb, in situ immunohistochemic analysis, overview
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the two isoforms CNP1 and CNP2 are differentially regulated during the process of maturation, CNP expression pattern
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myelinating, colocalization of CNPase and CaM during Schwann cell myelination in culture
additional information
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bovine peripheral nerve sheath tumors commonly have both schwannomatous and neurofibromatous areas
additional information
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spatiotemporal distribution of CNPase, an early oligodendrocyte/Schwann cell marker, overview
