3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase

This is an abbreviated version!
For detailed information about 2',3'-cyclic-nucleotide 3'-phosphodiesterase, go to the full flat file.

Word Map on EC 3.1.4.37

Reaction

nucleoside 2',3'-cyclic phosphate
+
H2O
=
Nucleoside 2'-phosphate

Synonyms

PNKP, 2',3'-cyclic AMP phosphodiesterase, cyclic 2',3'-nucleotide phosphodiesterase, 2',3'-cyclic nucleoside monophosphate phosphodiesterase, 2',3'-cyclic nucleotide phosphohydrolase, 2',3'-cyclic phosphodiesterase, 2',3'-cyclic nucleotide 3'-phosphohydrolase, CNPase, cyclic-CMP phosphodiesterase, cyclic 2',3'-nucleotide 3'-phosphodiesterase, phosphodiesterase, cyclic 2',3'-nucleotide 3'-, 2':3'-cyclic nucleotide 3'-phosphodiesterase, 2':3'-CNMP-3'-ase, nucleoside-2':3'-cyclic-phosphate 2'-nucleotidohydrolase, CNP, CNP1, CNP2, YtqI, 2',3'-cyclic nucleotide 3'-phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I, CNPase I, RocR, 2',3'-cyclic nucleotide-3'-phosphohydrolase, DGC2, YybT, 3DMA, PaAcpH, 2',3'-cyclic nucleotide phosphodiesterase, 2',3'-cyclic nucleotide-3'-phosphodiesterase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.4 Phosphoric-diester hydrolases
                3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase

Molecular Weight

Molecular Weight on EC 3.1.4.37 - 2',3'-cyclic-nucleotide 3'-phosphodiesterase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10000
-
sedimentation analysis in presence of bovine serum albumin, bovine brain
100000
110000
-
x * 110000 SDS-PAGE
120000
-
gel filtration, native conditions, bovine brain
128000
-
gel electrophoresis, second major band, microsomes
150000
-
GC-CNP/YN-Ub complex transfected MO3.13 cells, immunoblot analysis
23000
-
gel filtration
24000
-
x * 24000, SDS-PAGE
250000
-
GC-CNP/YN-Ub complex transfected MO3.13 cells, immunoblot analysis
263000
-
gel electrophoresis, first major band, microsomes
26700
-
x * 26700, SDS-PAGE, C-terminal domain. x * 45200, SDS-PAGE, full-length CNPase
30000
-
1 * 30000, SDS-PAGE
31000
33000
-
x * 33000, SDS-PAGE
36500
-
sedimentation coefficient
40000
-
2D electrophoresis and immunoblotting, lipid raft fraction from a young monkey
41200 - 43900
MALDI TOF mass spectrometry
44000
monomeric enzyme, light scattering and refractive index
44600
-
1 * 44600 + 1* 45900, SDS-PAGE
44850
-
sequence analysis, bovine brain
45100
-
sequence analysis, human brain
45200
-
x * 26700, SDS-PAGE, C-terminal domain. x * 45200, SDS-PAGE, full-length CNPase
47000
-
endogenous CNP, SDS-PAGE
47580
theoretical value
49000 - 51000
-
antibody column
50000
51000
-
x * 51000, SDS-PAGE
55000
-
gel filtration
60000
-
GC-CNP transfected MO3.13 cells, immunoblot analysis
74000
-
x * 74000, SDS-PAGE
78000
dimeric enzyme, light scattering and refractive index
additional information
-
in lipid raft fraction from an aged monkey, evidence of sequential CNP proteolysis, abundance of CNP immunoreactive higher molecular weight material