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Literature summary for 3.1.4.37 extracted from

  • Baburina, Y.; Odinokova, I.; Azarashvili, T.; Akatov, V.; Lemasters, J.J.; Krestinina, O.
    2',3'-Cyclic nucleotide 3'-phosphodiesterase as a messenger of protection of the mitochondrial function during melatonin treatment in aging (2017), Biochim. Biophys. Acta, 1859, 94-103 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside 2',3'-cyclic phosphate + H2O Rattus norvegicus
-
nucleoside 2'-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P13233
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2',3'-cAMP + H2O
-
Rattus norvegicus 2'-AMP
-
?
nucleoside 2',3'-cyclic phosphate + H2O
-
Rattus norvegicus nucleoside 2'-phosphate
-
?

Synonyms

Synonyms Comment Organism
2',3'-cyclic nucleotide 3'-phosphodiesterase
-
Rattus norvegicus
CNPase
-
Rattus norvegicus

General Information

General Information Comment Organism
physiological function melatonin retains the enzyme inside mitochondria, thereby providing the protection of the protein against deleterious effects of 2',3'-cAMP in aging Rattus norvegicus