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3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase

This is an abbreviated version!
For detailed information about 2',3'-cyclic-nucleotide 3'-phosphodiesterase, go to the full flat file.

Word Map on EC 3.1.4.37

Reaction

nucleoside 2',3'-cyclic phosphate
+
H2O
=
Nucleoside 2'-phosphate

Synonyms

2',3'-cyclic AMP phosphodiesterase, 2',3'-cyclic nucleoside monophosphate phosphodiesterase, 2',3'-cyclic nucleotide 3'-phosphodiesterase, 2',3'-cyclic nucleotide 3'-phosphohydrolase, 2',3'-cyclic nucleotide phosphodiesterase, 2',3'-cyclic nucleotide phosphohydrolase, 2',3'-cyclic nucleotide-3'-phosphodiesterase, 2',3'-cyclic nucleotide-3'-phosphohydrolase, 2',3'-cyclic phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I, 2':3'-CNMP-3'-ase, 2':3'-cyclic nucleotide 3'-phosphodiesterase, 3DMA, CNP, CNP1, CNP2, CNPase, CNPase I, cyclic 2',3'-nucleotide 3'-phosphodiesterase, cyclic 2',3'-nucleotide phosphodiesterase, cyclic-CMP phosphodiesterase, DGC2, nucleoside-2':3'-cyclic-phosphate 2'-nucleotidohydrolase, PaAcpH, phosphodiesterase, cyclic 2',3'-nucleotide 3'-, PNKP, RocR, YtqI, YybT

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.4 Phosphoric-diester hydrolases
                3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase

Specific Activity

Specific Activity on EC 3.1.4.37 - 2',3'-cyclic-nucleotide 3'-phosphodiesterase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.066
-
rabbit, adrenal gland
0.133
-
2',3'-cAMP, hole mitochondria
0.24
-
mitochondrial inner membrane
0.28
-
mitochondrial outer membrane
1.49
+/- 0.08, ADP
11.2
-
pH 6.2, 37°, treatment with lead
12.4
+/- 0.34, p-nitrophenyl phosphate
13.4
-
pH 6.2, 37°C
130.6
-
ZRICH-WT-enzyme
17.9
+/- 0.6, NADP
2.36
+/- 0.10, 2',3'-cGMP
2090
-
2',3'-cAMP
2140
-
2',3'-cCMP
2300
-
-
2680
-
-
280
-
2',3'-cGMP
3.01
+/- 0.06, diphosphate
3.21
+/- 0.1, 2',3'-cAMP
3.71
+/- 0.17, 2'-CMP
35
-
2',3'-cAMP, frog brain
4.03
+/- 0.20, CTP
4.53
+/- 0.14, ATP
5.8
+/- 0.47, CDP
6.28
-
2',3 '-cCMP, fish retina
600
-
2',3'-cUMP
800 - 2000
additional information