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Literature summary for 3.1.4.37 extracted from

  • Myllykoski, M.; Seidel, L.; Muruganandam, G.; Raasakka, A.; Torda, A.E.; Kursula, P.
    Structural and functional evolution of 2',3'-cyclic nucleotide 3'-phosphodiesterase (2016), Brain Res., 1641, 64-78 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Mus musculus 16020
-
membrane
-
Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside 2',3'-cyclic phosphate + H2O Mus musculus
-
nucleoside 2'-phosphate
-
?
nucleoside 2',3'-cyclic phosphate + H2O Rattus norvegicus
-
nucleoside 2'-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus P16330
-
-
Rattus norvegicus P13233
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Mus musculus
-
adrenal gland
-
Rattus norvegicus
-
central nervous system
-
Mus musculus
-
central nervous system
-
Rattus norvegicus
-
heart
-
Mus musculus
-
heart
-
Rattus norvegicus
-
lung
-
Mus musculus
-
lung
-
Rattus norvegicus
-
microglia
-
Mus musculus
-
microglia
-
Rattus norvegicus
-
myelin sheath
-
Mus musculus
-
myelin sheath
-
Rattus norvegicus
-
Schwann cell
-
Mus musculus
-
Schwann cell
-
Rattus norvegicus
-
spleen
-
Mus musculus
-
spleen
-
Rattus norvegicus
-
testis
-
Mus musculus
-
testis
-
Rattus norvegicus
-
thymus
-
Mus musculus
-
thymus
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2',3'-cAMP + H2O
-
Mus musculus 2'-AMP
-
?
2',3'-cAMP + H2O
-
Rattus norvegicus 2'-AMP
-
?
nucleoside 2',3'-cyclic phosphate + H2O
-
Mus musculus nucleoside 2'-phosphate
-
?
nucleoside 2',3'-cyclic phosphate + H2O
-
Rattus norvegicus nucleoside 2'-phosphate
-
?

Synonyms

Synonyms Comment Organism
2',3'-cyclic nucleotide 3'-phosphodiesterase
-
Mus musculus
2',3'-cyclic nucleotide 3'-phosphodiesterase
-
Rattus norvegicus
CNPase
-
Mus musculus
CNPase
-
Rattus norvegicus

Expression

Organism Comment Expression
Mus musculus enzyme expression is upregulated in activated microglia as a response to brain injury up
Rattus norvegicus enzyme expression is upregulated in activated microglia as a response to brain injury up

General Information

General Information Comment Organism
physiological function the enzyme interacts with microtubules and promotes tubulin polymerization Mus musculus
physiological function the enzyme interacts with microtubules and promotes tubulin polymerization Rattus norvegicus