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Literature summary for 3.1.4.37 extracted from

  • Gravel, M.; Robert, F.; Kottis, V.; Gallouzi, I.E.; Pelletier, J.; Braun, P.E.
    2,3-Cyclic nucleotide 3-phosphodiesterase: a novel RNA-binding protein that inhibits protein synthesis (2009), J. Neurosci. Res., 87, 1069-1079.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
wild type and mutant CNP proteins are produced in vitro in rabbit reticulocyte lysate in the presence of S-methionine Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
additional information CNP-CF is a CNP1 deletion mutant lacking the first 150 amino acids Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus CNP is an RNA-binding protein, CNP associates with poly(A)+ mRNAs in vivo and suppresses translation in vitro in a dose-dependent manner, isoform CNP1 may regulate expression of mRNAs in oligodendrocytes of the central nervous system ?
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
oligodendrocyte
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclic 2',3'-AMP + H2O
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Rattus norvegicus 2'-AMP
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?
additional information CNP is an RNA-binding protein, CNP associates with poly(A)+ mRNAs in vivo and suppresses translation in vitro in a dose-dependent manner, isoform CNP1 may regulate expression of mRNAs in oligodendrocytes of the central nervous system Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
2',3'-cyclic nucleotide 3'-phosphodiesterase
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Rattus norvegicus
CNP
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Rattus norvegicus
CNP1 isoform Rattus norvegicus