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Information on EC 1.6.5.2 - NAD(P)H dehydrogenase (quinone)
for references in articles please use BRENDA:EC1.6.5.2
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EC Tree 1 Oxidoreductases
1.6 Acting on NADH or NADPH
1.6.5 With a quinone or similar compound as acceptor
1.6.5.2 NAD(P)H dehydrogenase (quinone)
IUBMB Comments
A flavoprotein. The enzyme catalyses a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone . The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
- 1.6.5.2
- s-transferase
- dismutase
- oxygenase-1
- catalase
- gst
-
chemopreventive
-
detoxify
-
two-electron
- dicoumarol
-
2-related
-
erythroid
-
cytoprotective
- hydroquinone
-
bioreductive
- mitomycin
- sulforaphane
- isothiocyanate
- cyp1a1
- nitroreductase
-
decolor
- hepa
-
one-electron
-
glutamate-cysteine
-
benzoapyrene
-
nrf2-mediated
- semiquinone
-
chemoprotective
-
nadph-cytochrome
-
nrf2-dependent
-
kelch-like
-
drug-metabolizing
-
nf-e2-related
-
anticarcinogenic
- medicine
- glucosinolates
- plastoquinone
- nadph-d
-
textile
-
ech-associated
- 3-methylcholanthrene
-
xenobiotic-metabolizing
-
nrf2-are
-
udp-glucuronosyltransferase
-
erythroid-derived
-
ethoxyresorufin
- beta-naphthoflavone
- tert-butylhydroquinone
-
ferredoxin-nadp+
-
peitc
- pharmacology
- drug development
- analysis
- degradation
- methemoglobinemia
-
pentoxyresorufin
- biotechnology
showSynonyms
dt-diaphorase, diaphorase, quinone reductase, azoreductase, nad(p)h:quinone oxidoreductase 1, nad(p)h:quinone oxidoreductase, nad(p)h dehydrogenase, nad(p)h quinone oxidoreductase 1, ndh complex, nad(p)h quinone oxidoreductase, more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
azoreductase
chromate reductase
ChrR
dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone)
-
-
-
-
diaphorase
-
-
-
-
DT-diaphorase
DTD
DVU_2399
DVU_2400
DVU_2401
EC 1.6.99.2
FerB
ferric reductase B
flavoprotein NAD(P)H-quinone reductase
-
-
-
-
FlxABCD
MdaB
Menadione oxidoreductase
-
-
-
-
Menadione reductase
-
-
-
-
NAD(P)H dehydrogenase
-
-
-
-
NAD(P)H menadione reductase
-
-
-
-
NAD(P)H quinone reductase
NAD(P)H quinone-oxidoreductase 1
NAD(P)H-QR
NAD(P)H-quinone dehydrogenase
-
-
-
-
NAD(P)H-quinone oxidoreductase
NAD(P)H: (quinone-acceptor)oxidoreductase
-
-
-
-
NAD(P)H: menadione oxidoreductase
-
-
-
-
NAD(P)H: Quinone oxidoreductase
NAD(P)H: quinone oxidoreductase 1
NAD(P)H:acceptor oxidoreductase
NAD(P)H:quinone acceptor oxidoreductase
NAD(P)H:quinone oxidoreductase
NAD(P)H:quinone oxidoreductase 1
NAD(P)H:quinone oxidoreductase I
NAD(P)H:quinone reductase
NADH-menadione reductase
-
-
-
-
NADPH quinone reductase
NADPH:quinone oxidoreductase
NADPH:quinone oxidoreductase 1
Naphthoquinone reductase
-
-
-
-
NQO1
p-Benzoquinone reductase
-
-
-
-
Pden_4071
Phylloquinone reductase
-
-
-
-
QR1
QR2
-
-
-
-
Quinone reductase
quinone reductase 1
quinone reductase type 1
Reduced NAD(P)H dehydrogenase
-
-
-
-
reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase
-
-
-
-
Viologen accepting pyridine nucleotide oxidoreductase
-
-
-
-
Vitamin K reductase
vitamin-K reductase
-
-
-
-
WrbA
azoreductase
-
-
-
-
DT-diaphorase
-
-
-
-
DTD
-
-
-
-
NAD(P)H-quinone oxidoreductase
-
-
-
-
NAD(P)H:quinone oxidoreductase 1
-
-
NADPH:quinone oxidoreductase 1
-
wild type NQO1, variant NQO1*2 induces an amino acid change P187S
NQO1
-
-
NQO1
-
-
QR1
-
-
-
-
Quinone reductase
-
-
-
-
Vitamin K reductase
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
-
-
-
-
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
ping-pong mechanism
-
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
ordered bi-bi mechanism
-
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
ping-pong reaction mechanism
-
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
specific conformations of Y128 and F232 on the surface of the catalytic pocket are important for interaction of enzyme with p53 and other client proteins
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
ping-pong mechanism with substrate inhibition
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
the activity obeys the standard bi-bi ping-pong reaction mechanism
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
the activity obeys the standard bi-bi ping-pong reaction mechanism
-
-
NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone
reaction mechanism
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
redox reaction
-
-
-
-
reduction
oxidation
-
-
-
-
reduction
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
MetaCyc
superpathway of photosynthetic hydrogen production, vitamin K-epoxide cycle
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SYSTEMATIC NAME
IUBMB Comments
NAD(P)H:quinone oxidoreductase
A flavoprotein. The enzyme catalyses a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone [6]. The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.
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CAS REGISTRY NUMBER
COMMENTARY
9032-20-6
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,4-benzoquinone + NADPH
1,4-benzosemiquinone + NADP+
-
Substrates: -
Products: -
Products: -
?
1,4-dimethoxymethylbenzoquinone + NAD(P)H
1,4-dimethoxymethylhydrobenzoquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1,4-naphthoquinone + NADPH + H+
1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
1,4-naphthoquinone + NADPH + H+
1,4-naphthosemiquinone + NADP+
-
Substrates: -
Products: -
Products: -
?
1,4-tetramethylbenzoquinone + NAD(P)H
1,4-tetramethylhydrobenzoquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1,8-dihydroxy-9,10-anthraquinone + NADPH
1,8-dihydroxy-9,10-anthraquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
1-hydroxy-2-[2-(nitrooxy)ethyl]-1-oxo-2-(2,4,6-trinitro-3-(nitro[2-(nitrooxy)ethyl]amino)phenyl)diazanium + NAD(P)H + H+
reduced 1-hydroxy-2-[2-(nitrooxy)ethyl]-1-oxo-2-(2,4,6-trinitro-3-(nitro[2-(nitrooxy)ethyl]amino)phenyl)diazanium + NAD(P)+
-
Substrates: -
Products: ratio kcat to Km value is 52000 per M and s
Products: ratio kcat to Km value is 52000 per M and s
?
1-hydroxy-9,10-anthraquinone + NADPH
1-hydroxy-9,10-anthraquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
17-(2-dimethylylamino)ethylamino-17-demethoxygeldanamycin + NAD(P)H + H+
reduced 17-(2-dimethylylamino)ethylamino-17-demethoxygeldanamycin + NADP+
-
Substrates: -
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
?
17-(2-pyrrolidin-1-yl)ethylamino-17-demethoxygeldanamycin + NAD(P)H + H+
reduced 17-(2-pyrrolidin-1-yl)ethylamino-17-demethoxygeldanamycin + NADP+
-
Substrates: -
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
?
17-allylamino-17-demethoxygeldanamycin + NAD(P)H + H+
reduced 17-allylamino-17-demethoxygeldanamycin + NADP+
-
Substrates: -
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
?
17-amino-17-demethoxygeldanamycin + NAD(P)H + H+
reduced 17-amino-17-demethoxygeldanamycin + NADP+
-
Substrates: -
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
Products: reduced component is a more potent Hsp90 inhibitor than parent benzoquinone ansamycin
?
2 ferricyanide + NADH
2 ferrocyanide + NAD+ + H+
-
Substrates: 60% activity compared to the reactions of NADPH or NADH with 2,3-dimethoxy-5-methyl-1,4-benzoquinone
Products: -
Products: -
?
2,3,3-trimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-dione + NADH + H+
2,3,3-trimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-diol + NAD+
Substrates: -
Products: -
Products: -
?
2,3,5,6-tetramethyl-1,4-benzoquinone + NAD(P)H
reduced 2,3,5,6-tetramethyl-1,4-benzoquinone + NAD(P)+
Substrates: -
Products: -
Products: -
?
2,3-diglutathionyl-1,4-naphthoquinone + NADPH
2,3-diglutathionyl-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,3-dihydroxy-5-methyl-1,4-benzoquinone + NAD(P)H
2,3-dihydroxy-5-methyl-1,4-benzoquinol + NAD(P)+
2,3-dimethyl-1,4-naphthoquinone + NAD(P)H
2,3-dimethyl-1,4-hydronaphthoquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2,4,6-trinitrotoluene + NAD(P)H +
reduced 2,4,6-trinitrotoluene + NAD(P)+
-
Substrates: -
Products: ratio kcat to Km value is 670 per M and s
Products: ratio kcat to Km value is 670 per M and s
?
2,5-bis(aziridin-1-yl)-3,6-dimethylcyclohexa-2,5-diene-1,4-dione + NAD(P)H
2,5-bis(aziridin-1-yl)-3,6-dimethylbenzene-1,4-diol + NAD(P)+
Substrates: excellent substrate
Products: -
Products: -
?
2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexane-1,4-dione + NAD(P)H
2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylbenzene-1,4-diol + NAD(P)+
Substrates: excellent substrate
Products: -
Products: -
?
2,5-bis(ethylamine)-3,6-diaziridinyl-1,4-benzoquinone + NADPH
2,5-bis(ethylamine)-3,6-diaziridinyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,5-di-tert-butyl-1,4-benzoquinone + NADH
2,5-di-tert-butyl-1,4-benzoquinol + NAD+
Substrates: -
Products: -
Products: -
?
2,5-diaziridinyl-1,4-benzoquinone + NADPH
2,5-diaziridinyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone + NADPH
2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,5-dihydroxy-1,4-naphthoquinone + NADPH
2,5-dihydroxy-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,5-dimethoxy-1,3-benzothiazole-4,7-dione + NAD(P)H
2,5-dimethoxy-1,3-benzothiazole-4,7-diol + NAD(P)+
Substrates: -
Products: -
Products: -
?
2,5-dimethoxy-1-methyl-1H-benzimidazole-4,7-dione + NAD(P)H
2,5-dimethoxy-1-methyl-1H-benzimidazole-4,7-diol + NAD(P)+
Substrates: -
Products: -
Products: -
?
2,5-dimethyl-1,4-benzoquinone + NADPH
2,5-dimethyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,5-dimethyl-1,4-naphthoquinone + NADPH
2,5-dimethyl-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone + NADPH
2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2,6-dichlorophenolindophenol + NADPH
reduced 2,6-dichlorophenolindophenol + NADP+
Substrates: -
Products: -
Products: -
?
2,6-dimethoxy-1,4-benzoquinone + NADH
2,6-dimethoxy-1,4-benzoquinol + NAD+
Substrates: -
Products: -
Products: -
?
2,6-dimethoxybenzoquinone + NAD(P)H
2,6-dimethoxyhydrobenzoquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2,6-dimethyl-1,4-benzoquinone + NADPH
2,6-dimethyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-(1-hydroxyethyl)-5-methoxy-3-methyl-1-benzofuran-4,7-dione + NADH + H+
2-(1-hydroxyethyl)-5-methoxy-3-methyl-1-benzofuran-4,7-diol + NAD+
Substrates: -
Products: -
Products: -
?
2-acetoxymethyl-6-methoxy-1-methylbenzimidazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
Products: -
Products: -
?
2-chloro-6-hydroxy-1,4-benzoquinone + NADH
6-chlorobenzene-1,2,4-triol + NAD+
-
Substrates: -
Products: -
Products: -
?
2-ethyl-1,4-naphthoquinone + NAD(P)H
2-ethyl-1,4-hydronaphthoquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2-hydroxy-1,4-naphthoquinone + NADPH
2-hydroxy-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-hydroxymethyl-5-methoxy-1-methylbenzimidazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
Products: -
Products: -
?
2-hydroxymethyl-5-methoxy-2,5-cyclohexadiene-1,4-dione + NAD(P)H
2-hydroxymethyl-5-methoxy-2,5-cyclohexadiene-1,4-diol + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2-hydroxymethyl-5-methoxybenzothiazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
Products: -
Products: -
?
2-hydroxymethyl-6-methoxy-1-methylbenzimidazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
Products: -
Products: -
?
2-methoxy-1,4-benzoquinone + NADPH
2-methoxy-1,4-benzoquinol + NADP+
Substrates: -
Products: -
Products: -
?
2-methoxy-2,5-cyclohexadiene-1,4-dione + NAD(P)H
2-methoxy-2,5-cyclohexadiene-1,4-diol + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2-methoxy-5-(methoxymethyl)-2,5-cyclohexadiene + NADH + H+
2-methoxy-5-methoxymethyl-2,5-cyclohexadiene-1,4-diol + NAD+
-
Substrates: -
Products: -
Products: -
r
2-methoxy-5-(methoxymethyl)-2,5-cyclohexadiene-1,4-dione + NAD(P)H
2-methoxy-5-methoxymethyl-2,5-cyclohexadiene-1,4-diol + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2-methoxyquinone + NAD(P)H
2-methoxyhydroquinone + NAD(P)+
Sporotrichum pulverulentum
-
Substrates: -
Products: -
Products: -
?
2-methyl-1,4-benzoquinone + NADPH
2-methyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-methyl-1,4-naphthoquinone + NAD(P)H
2-methyl-1,4-dihydronaphthoquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
2-methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinone + NADPH
2-methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-methyl-3-hydroxy-1,4-naphthoquinone + NADPH
2-methyl-3-hydroxy-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-methyl-3-phytyl-1,4-naphthoquinone + NAD(P)H
2-methyl-3-phytyl-1,4-naphthohydroquinone + NAD(P)+
2-methyl-5-aziridinyl-1,4-benzoquinone + NADPH
2-methyl-5-aziridinyl-1,4-benzoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-methyl-5-hydroxy-1,4-naphthoquinone + NADPH
2-methyl-5-hydroxy-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
2-[nitro(2,4,6-trinitrophenyl)amino]ethyl nitrate + NAD(P)H +
reduced 2-[nitro(2,4,6-trinitrophenyl)amino]ethyl nitrate + NAD(P)+
-
Substrates: -
Products: ratio kcat to Km value is 570000 per M and s
Products: ratio kcat to Km value is 570000 per M and s
?
3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione + NAD(P)H
3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-diol + NAD(P)+
-
Substrates: trivial name beta-lapachone, potent cytotoxic agent against various cancer cell lines
Products: -
Products: -
?
3-(1-hydroxyethyl)-5-methoxy-2-methyl-1-benzofuran-4,7-dione + NADH + H+
3-(1-hydroxyethyl)-5-methoxy-2-methyl-1-benzofuran-4,7-diol + NAD+
Substrates: -
Products: -
Products: -
?
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide + NAD(P)H
reduced 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide + NAD(P)+
3-(hydroxymethyl)-5-methoxy-1-methyl-1H-indazole-4,7-dione + NADH + H+
3-(hydroxymethyl)-5-methoxy-1-methyl-1H-indazole-4,7-diol + NAD+
Substrates: -
Products: -
Products: -
?
3-(hydroxymethyl)-5-methoxy-1-methyl-2-phenyl-1H-indole-4,7-dione + NAD(P)H
3-(hydroxymethyl)-5-methoxy-1-methyl-2-phenyl-1H-indole-4,7-diol + NAD(P)+
Substrates: excellent substrate
Products: -
Products: -
?
4,5,6,7-tetranitro-1,3-dihydro-2H-benzimidazol-2-one + NAD(P)H +
reduced 4,5,6,7-tetranitro-1,3-dihydro-2H-benzimidazol-2-one + NAD(P)+
-
Substrates: -
Products: ratio kcat to Km value is 5000000 per M and s
Products: ratio kcat to Km value is 5000000 per M and s
?
4,5,6-trinitro-1,3-dihydro-2H-benzimidazol-2-one + NAD(P)H +
reduced 4,5,6-trinitro-1,3-dihydro-2H-benzimidazol-2-one + NAD(P)+
-
Substrates: -
Products: ratio kcat to Km value is 26000 per M and s
Products: ratio kcat to Km value is 26000 per M and s
?
4,5-dimethoxy-3,5-cyclohexadiene-1,2-dione
4,5-dimethoxy-3,5-cyclohexadiene-1,2-diol + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
5,8-dihydroxy-1,4-naphthoquinone + NADPH
5,8-dihydroxy-1,4-naphthoquinol + NADP+
-
Substrates: -
Products: -
Products: -
?
5,8-dihydroxynaphthoquinone + NAD(P)H
5,8-dihydroxynaphthohydroquinone + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-1H-indole-4,7-dione + NAD(P)H
5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-1H-indole-4,7-diol + NAD(P)+
5-(aziridin-1-yl)-2,4-dinitrobenzamide + NAD(P)H
5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide + NAD(P)+
5-(aziridin-1-yl)-2,4-dinitrobenzamide + reduced dihydronicotineamide riboside
5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide + oxidized dihydronicotineamide riboside
5-aziridin-1-yl-2,4-dinitrobenzamide + NAD(P)H + H+
5-aziridin-1-yl-4-(hydroxyamino)-2-nitrobenzamide
-
Substrates: i.e. CB1954, anticancer prodrug
Products: -
Products: -
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5-aziridin-1-yl-3-(hydroxymethyl)-2-[(1E)-3-hydroxyprop-1-en-1-yl]-1-methyl-1H-indole-4,7-dione + NAD(P)H
5-aziridin-1-yl-3-(hydroxymethyl)-2-[(1E)-3-hydroxyprop-1-en-1-yl]-1-methyl-1H-indole-4,7-diol + NAD(P)+
Substrates: -
Products: -
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5-hydroxy-1,4-naphthoquinone + NADPH
5-hydroxy-1,4-naphthosemiquinone + NADP+
-
Substrates: -
Products: -
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5-methoxy-1,2-dimethyl-3-(hydroxymethyl)indole-4,7-dione + NADH
? + NAD+
Substrates: is efficiently metabolized by NQO1
Products: -
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5-methoxy-1,2-dimethyl-3-[(phenoxy)methyl]indole-4,7-dione + NADH
? + NAD+
Substrates: inefficient indolequinone substrate
Products: -
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5-methoxy-2-methylbenzothiazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
Products: -
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5-methoxy-4,7-dioxo-4,7-dihydro-1-benzothiophene-2-carboxylic acid + NADH + H+
4,7-dihydroxy-5-methoxy-1-benzothiophene-2-carboxylic acid + NAD+
Substrates: -
Products: -
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6-hydroxydopaminequinone + NAD(P)H
6-hydroxydopaminehydroquinone + NAD(P)+
-
Substrates: -
Products: -
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6-hydroxydopaquinone + NAD(P)H
6-hydroxydopahydroquinone + NAD(P)+
-
Substrates: -
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6-methoxy-1,2-dimethyl-3-(hydroxymethyl)indole-4,7-dione + NADH
? + NAD+
Substrates: is efficiently metabolized by NQO1
Products: -
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6-methoxy-1,2-dimethyl-3-[(phenoxy)methyl]indole-4,7-dione + NADH
? + NAD+
Substrates: inefficient indolequinone substrate
Products: -
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6-methoxy-1-methyl-2-(4-nitrophenoxymethyl)benzimidazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
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6-methoxy-1-methylbenzimidazole-4,7-dione + NADH
? + NAD+
-
Substrates: -
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7-N-(2-furoyl)demethyllavendamycin methyl ester + NADH
? + NAD+
Substrates: poor substrate
Products: -
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7-N-acetyldemethyllavendamycin n-butyl amide + NADH
? + NAD+
Substrates: good substrate
Products: -
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7-N-acetyldemethyllavendamycin sec-butyl amide + NADH
? + NAD+
Substrates: poor substrate
Products: -
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8-methoxy-2,3,3-trimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-dione + NADH + H+
8-methoxy-2,3,3-trimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-diol + NAD+
Substrates: -
Products: -
Products: -
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9,10-anthraquinone-2,6-disulfonate + NADPH
? + NADP+