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BRENDA support

Literature summary for 1.6.5.2 extracted from

  • Cui, X.; Jin, T.; Wang, X.; Jin, G.; Li, Z.; Lin, L.
    NAD(P)H quinone oxidoreductase-1 overexpression predicts poor prognosis in small cell lung cancer (2014), Oncol. Rep., 32, 2589-2595 .
    View publication on PubMed

Application

Application Comment Organism
medicine levels of NQO1 protein and mRNA are significantly elevated in fresh tissue samples of small cell lung cancer. The rate of strong positive NQO1 protein expression is significantly higher in small cell lung cancer when compared with the rate in either adjacent non-cancerous or normal lung tissues and correlated with large tumor size, late pathologic stage and the presence of lymph node metastasis. High?level expression of NQO1 protein is significantly correlated with lower disease-free survival and 5-year survival rates in patients Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P15559
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Source Tissue

Source Tissue Comment Organism Textmining
small cell lung cancer cell
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Homo sapiens
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