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BRENDA support

Ligand NADPH

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Basic Ligand Information

Molecular Structure
Picture of NADPH (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H30N7O17P3
NADPH
ACFIXJIJDZMPPO-NNYOXOHSSA-N
Synonyms:
2'-NADPH, beta-NADPH, NAD(P)H, NAPDH, Nicotinamide adenine dinucleotide-diphosphate
Pathway Source
Pathways
BRENDA
3-chlorocatechol degradation, 3-phenylpropionate degradation, 4-hydroxymandelate degradation, acetate fermentation, acetyl CoA biosynthesis more
KEGG
Alcoholic liver disease, Aldosterone synthesis and secretion, Chemical carcinogenesis - reactive oxygen species, Diabetic cardiomyopathy, Glutathione metabolism more
MetaCyc
(+)-pisatin biosynthesis, (-)-glycinol biosynthesis, (-)-maackiain biosynthesis, (-)-medicarpin biosynthesis, (1'S,5'S)-averufin biosynthesis more


Show all pahtways known for Show all BRENDA pathways known for NADPH

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3831 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-(4-hydroxyphenyl)pyruvate + NAD(P)H = (R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
show the reaction diagram
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fructose + NADPH = sorbitol + NADP+
show the reaction diagram
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(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH = 2-dehydro-3-deoxy-D-gluconate + NADP+
show the reaction diagram
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2,5-didehydro-3-deoxy-D-gluconate + NADPH + H+ = 2-dehydro-3-deoxy-D-gluconate + NADP+
show the reaction diagram
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(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H = 3-dehydro-L-gulonate + NAD(P)+
show the reaction diagram
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D-mannuronate + NADPH = D-mannonate + NADP+
show the reaction diagram
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TDP-6-deoxy-D-xylo-4-hexosulose + NADPH = TDP-6-deoxy-L-talose + NADP+
show the reaction diagram
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GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H = GDP-6-deoxy-D-talose + NAD(P)+
show the reaction diagram
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D-fructose + NADPH = D-mannitol + NADP+
show the reaction diagram
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3-acetoacetyl-CoA + NADPH + H+ = (S)-3-hydroxybutanoyl-CoA + NADP+
show the reaction diagram
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(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH = ?
show the reaction diagram
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diacetyl + NAD(P)H = acetoin + NADP+
show the reaction diagram
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D-fructose 6-phosphate + NADPH + H+ = D-mannitol 1-phosphate + NADP+
show the reaction diagram
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12-oxolithocholic acid + NADPH + H+ = deoxycholic acid + NADP+
show the reaction diagram
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indole-3-acetaldehyde + NADPH = indole-3-ethanol + NADP+
show the reaction diagram
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D-glucose 6-phosphate + NADPH + H+ = D-sorbitol 6-phosphate + NADP+
show the reaction diagram
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