Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HCT-116 cell | - |
Homo sapiens | - |
HEK-293 cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
NAD(P)H:quinone oxidoreductase 1 | - |
Homo sapiens |
NQO1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | NQO1, a 20S proteasome gatekeeper, binds and induces robust c-Fos accumulation by blocking the ubiquitin-independent degradation pathway. NQO1 protects monomeric c-Fos from proteasomal ubiquitin-independent degradation. NQO1 is important to ensure immediate c-Fos accumulation in response to serum | Homo sapiens |