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Literature summary for 1.6.5.2 extracted from
- Transcriptional regulation of the NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and copper (2006), Drug Metab. Dispos., 34, 152-165.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | decrease of enzyme mRNA expression, via a transcriptional mechanism | Mus musculus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Hg2+ | increase of enzyme mRNA expression, via a transcriptional mechanism | Mus musculus | |
| Pb2+ | increase of enzyme mRNA expression, via a transcriptional mechanism | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hepa-1c1c7 cell | hepatoma cell line | Mus musculus | - |
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