Reference on EC 3.2.1.24 - alpha-mannosidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vazquez-Reyna, A.B.; Ponce-Noyola, P.; Calvo-Mendez, C.; Lopez-Romero, E.; Flores-Carreon, A.
Purification and biochemical characterization of two soluble alpha-mannosidases I and II from Candida albicans
Glycobiology
9
533-537
1999
Candida albicans
Jin, Y.Z.; Dacheux, F.; Dacheux, J.L.; Bannai, S.; Sugita, Y.; Okamura, N.
Purification and properties of major alpha-D-mannosidase in the luminal fluid of porcine epididymis
Biochim. Biophys. Acta
1432
382-392
1999
Sus scrofa
Porwoll, S.; Fuchs, H.; Tauber, R.
Characterization of a soluble class I alpha-mannosidase in human serum
FEBS Lett.
449
175-178
1999
Homo sapiens
Vallee, F.; Lal, A.; Moremen, K.W.; Howell, P.L.
Purification, crystallization and preliminary X-ray crystallographic analysis of recombinant murine Golgi mannosidase IA, a class I alpha-mannosidase involved in Asn-linked oligosaccharide maturation
Acta Crystallogr. Sect. D
55
571-573
1999
Mus musculus
Vandersall-Nairn, A.S.; Merkle, R.K.; O'Brien, K.; Oeltmann, T.N.; Moremen, K.W.
Cloning, expression, purification, and characterization of the acid alpha-mannosidase from Trypanosoma cruzi
Glycobiology
8
1183-1194
1998
Trypanosoma cruzi
Beccari, T.; Appolloni, M.G.; Costanzi, E.; Stinchi, S.; Stirling, J.L.; Della Fazia, M.A.; Servillo, G.; Viola, M.P.; Orlacchio, A.
Lysosomal alpha-mannosidases of mouse tissues: characteristics of the isoenzymes, and cloning and expression of a full-length cDNA
Biochem. J.
327
45-49
1997
Mus musculus (O09159), Mus musculus
Merkle, R.K.; Zhang, Y.; Ruest, P.J.; Lal, A.; Liao, Y.F.; Moremen, K.W.
Cloning, expression, purification, and characterization of the murine lysosomal acid alpha-mannosidase
Biochim. Biophys. Acta
1336
132-146
1997
Mus musculus (O09159), Mus musculus
Yamashiro, K.; Itoh, H.; Yamagishi, M.; Natsuka, S.; Mega, T.; Hase, S.
Purification and characterization of neutral alpha-mannosidase from hen oviduct: studies on the activation mechanism of Co2+
J. Biochem.
122
1174-1181
1997
Gallus gallus
Liao, Y.F.; Lal, A.; Moremen, K.W.
Cloning, expression, purification, and characterization of the human broad specificity lysosomal acid alpha-mannosidase
J. Biol. Chem.
271
28348-28358
1996
Homo sapiens
Gaikwald, S.M.; Keskar, S.S.; Khan, M.I.
Purification and characterization of alpha-D-mannosidase from Aspergillus sp.
Biochim. Biophys. Acta
1250
144-148
1995
Aspergillus sp.
Schneikert, J.; Herscovics, A.
Characterization of a novel mouse recombinant processing alpha-mannosidase
Glycobiology
4
445-450
1994
Mus musculus
Grarg, T.; Saint-Pol, A.; Haeuw, J.F.; Alonso, C.; Wieruszeski, J.M.; Strecker, G.; Michalski, J.C.
Soluble forms of alpha-D-mannosidases from rat liver. Separation and characterization of two enzymic forms with different substrate specificities
Eur. J. Biochem.
223
99-106
1994
Rattus sp.
Tulsiani, D.R.P.; Skudlarek, M.D.; Nagdas, S.K.; Orgebin-Crist, M.C.
Purification and characterization of rat epididymal-fluid alpha-D-mannosidase: similarities to sperm plasma-membrane alpha-D-mannosidase
Biochem. J.
290
427-436
1993
Rattus sp.
-
Vazquez-Reyna, A.B.; Balcazar-Orozco, R.; Flores-Carreon, A.
Biosynthesis of glycoproteins in Candida albicans: Biochemical characterization of a soluble alpha-mannosidase
FEMS Microbiol. Lett.
106
321-326
1993
Candida albicans
Swanson, P.M.; Carter, C.E.; Hager, C.; Kim, W.J.; Obermeier, S.; Oeltmann, T.N.
Identification and characterization of an alpha-mannosidase from Trypanosoma cruzi
Glycobiology
2
563-569
1992
Trypanosoma cruzi
Moremen, K.W.; Touster, O.; Robbins, P.W.
Novel purification of the catalytic domain of golgi alpha-mannosidase II. Characterization and comparison with the intact enzyme
J. Biol. Chem.
266
16876-16885
1991
Rattus sp.
Bischoff, J.; Moremen, K.; Lodish, H.F.
Isolation, characterization, and expression of cDNA encoding a rat liver endoplasmatic reticulum alpha-mannosidase
J. Biol. Chem.
265
17110-17117
1990
Rattus sp.
Bonay, P.; Hughes, R.C.
Purification and characterization of a novel broad-specificity (alpha1-2, alpha1-3 and alpha1-6) mannosidase from rat liver
Eur. J. Biochem.
197
229-238
1991
Rattus sp.
Lopez-Valbuena, R.; Jorrin, J.; Polanco, A.; Tena, M.
Purification and partial characterization of soluble alpha-mannosidase isoforms from sunflower (Helianthus annuus L.) hypocotyls
Plant Sci.
62
11-19
1989
Helianthus annuus
-
Gunnarsson, A.; Svensson, S.
Studies of the reversed alpha-mannosidase reaction in high concentrations of mannose
Enzyme Microb. Technol.
11
347-352
1989
Canavalia ensiformis
-
Tanimoto, K.; Katsuragi, T.; Yamaguchi, H.
Induction and purification of Aspergillus oryzae 1,2-alpha-mannosidase
Agric. Biol. Chem.
53
1083-1088
1989
Aspergillus oryzae
-
Einhoff, W.; Rudiger, H.
The alpha-mannosidase from Canavalia ensiformes seeds: chemical and kinetic properties and action on animal lymphocytes
Biol. Chem. Hoppe-Seyler
369
165-169
1988
Canavalia ensiformis
Yoshihisa, T.; Ohsumi, Y.; Anraku, Y.
Solubilization and purification of alpha-mannosidase, a marker-enzyme of vacuolar membranes in Saccharomyces cerevisiae
J. Biol. Chem.
263
5158-5163
1988
Saccharomyces cerevisiae
Niyogi, K.; Singh, M.
An immunological distinct form of alpha-mannosidase in Canavalia ensiformis leaf
Phytochemistry
27
2737-2741
1988
Canavalia ensiformis
-
Vega, R.; Dominguez, A.
Partial characterization of alpha-mannosidase from Yarrowia lipolytica
J. Basic Microbiol.
28
371-379
1988
Yarrowia lipolytica
-
Mathur, R.; Panneerselvam, K.; Balasubramanian, A.S.
Co2+-mediated time- and temperature-dependend activation of neutral alpha-D-mannosidase from monkey brain
Biochem. J.
253
677-685
1988
Macaca radiata
Tulsiani, D.R.P.; Coleman, V.D.; Touster, O.
Rat epididymal alpha-D-mannosidase: purification, carbohydrate composition, substrate specificity, and antibody production
Arch. Biochem. Biophys.
267
60-68
1988
Rattus sp.
Zacharova, I.Y.; Tamm, V.Y.; Pavlova, I.N.
Alpha-mannosidase from Rhodococcus erythropolis
Methods Enzymol.
160
620-626
1988
Rhodococcus erythropolis
-
Conti, S.; Carratu, G.; Giannattasio, M.
Alpha-D-mannosidase from the aleurone layers of resting wheat grains: sugar-depleted forms
Phytochemistry
26
2909-2912
1987
Triticum aestivum
-
Waln, K.T.; Poulton, J.E.
Partial purification and characterization of an alpha-D-mannosidase from mature seeds of Prunus serotina Ehrh.
Plant Sci.
53
1-10
1987
Prunus serotina
-
Nakagawa, H.; Enomoto, N.; Asakawa, M.; Uda, Y.
Purification and characterization of alpha-mannosidase and beta-N-acetylhexosaminidase from watermelon fruit
Agric. Biol. Chem.
52
2223-2230
1988
Citrullus lanatus
-
Cheng, S.H.; Malcolm, S.; Pemble, S.; Winchester, B.
Purification and comparison of the structures of human liver acidic alpha-D-mannosidases A and B
Biochem. J.
233
65-72
1986
Homo sapiens
Shigematsu, Y.; Tsukahara, K.; Tanaka, T.; Takeuchi, M.; Ichishima, E.
Molecular and enzymic properties of 1,2-alpha-D-mannosidase from Aspergillus saitoi
Curr. Microbiol.
13
43-46
1986
Aspergillus phoenicis
-
Szumilo, T.; Kaushal, G.P.; Hori, H.; Elbein, A.D.
Purification and properties of a glycoprotein processing alpha-mannosidase from mung bean seedlings
Plant Physiol.
81
383-389
1986
Vigna radiata
Tulsiani, D.R.P.; Touster, O.
Characterization of a novel alpha-D-mannosidase from rat brain microsomes
J. Biol. Chem.
260
13081-13087
1985
Rattus sp.
Okumura, T.; Yamashina, I.
Further purification and characterization of alpha-mannosidase from hog kidney
J. Biochem.
73
131-138
1973
Sus scrofa
Shigeta, S.; Kubota, H.; Tamura, H.
Purification and characterization of an alpha-mannosidase of sea-squirt
J. Biochem.
94
1827-1832
1983
Styela plicata
Van der Wilden, W.; Chrispeels, M.J.
Characterization of the isoenzymes of alpha-mannosidase located in the cell wall, protein bodies, and endoplasmatic reticulum of Phaseolus vulgaris cotyledons
Plant Physiol.
71
82-87
1983
Phaseolus vulgaris
Bischoff, J.; Kornfeld, R.
Evidence for an alpha-mannosidase in endoplasmatic reticulum of rat liver
J. Biol. Chem.
258
7907-7910
1983
Rattus sp.
Tulsiani, D.R.P.; Hubbard, S.C.; Robbins, P.W.; Touster, O.
alpha-D-Mannosidases of rat liver Golgi membranes. Mannosidase II is the GlcNAcMAN5-cleaving enzyme in glycoprotein biosynthesis and mannosidases Ia and IB are the enzymes converting Man9 precursors to Man5 intermediates
J. Biol. Chem.
257
3660-3668
1982
Rattus sp.
Plant, A.R.; Moore, K.G.
alpha-D-Mannosidase and alpha-D-galactosidase from protein bodies of Lupinus angustifolius cotyledons
Phytochemistry
21
985-989
1982
Lupinus angustifolius
-
Yamamoto, K.; Hitomi, J.; Kobatake, K.; Yamaguchi, H.
Purification and characterization of 1,2-alpha-mannosidase of Aspergillus oryzae
J. Biochem.
91
1971-1979
1982
Aspergillus oryzae
Ichishima, E.; Arai, M.; Shigematsu, Y.; Kumagai, H.; Sumida-Tanaka, R.
Purification of an acidic alpha-D-mannosidase from Aspergillus satoi and specific cleavage of 1,2-alpha-D-mannosidic linkage in yeast mannan
Biochim. Biophys. Acta
658
45-53
1981
Aspergillus phoenicis
Forsee, W.T.; Schutzbach, J.S.
Purification and characterization of a phospholipid-dependent alpha-mannosidase from rabbit liver
J. Biol. Chem.
256
6577-6582
1981
Oryctolagus cuniculus
Curdel, A.; Petek, F.
Purification and properties of alpha-D-mannosidase from germinated seeds of Medicago sativa (alfalfa)
Biochem. J.
185
455-462
1980
Medicago sativa
Poenaru, L.; Dreyfus, J.C.
alpha-Mannosidase in human red cells
Biochim. Biophys. Acta
566
67-71
1979
Homo sapiens
Hirani, S.; Winchester, B.
The multiple forms of alpha-D-mannosidase in human plasma
Biochem. J.
179
583-592
1979
Homo sapiens
Opheim, D.J.; Touster, O.
Lysosomal alpha-D-mannosidase of rat liver. Purification and comparison with the golgi and cytosolic alpha-D-mannosidases
J. Biol. Chem.
253
1017-1023
1978
Rattus sp.
Opheim, D.J.; Touster, O.
alpha-D-Mannosidase from rat liver lysosomes
Methods Enzymol.
50
494-500
1978
Rattus sp.
Opheim, D.J.
alpha-D-Mannosidase of Saccharomyces cerevisiae. Characterization and modulation of activity
Biochim. Biophys. Acta
524
121-130
1978
Saccharomyces cerevisiae
Augustin, J.; Sikl, D.; Zemek, J.
Properties of extracellular alpha-mannosidase from Aspergillus flavus
Collect. Czech. Chem. Commun.
43
2812-2816
1978
Aspergillus flavus
-
Katohda, S.; Sawaya, Y.; Asatsuma, K.; Suzuki, F.; Hayashibe, M.
Purification and some properties of alpha-mannosidase
Agric. Biol. Chem.
41
331-337
1977
Acinetobacter sp.
-
Kaya, T.; Aikawa, M.; Matsumoto, T.
Purification and properties of alpha-mannosidase from baker's yeast
J. Biochem.
82
1443-1449
1977
Saccharomyces cerevisiae
Paus, E.
Alpha-mannosidase from Phaseolus vulgaris. Composition and structural properties
Eur. J. Biochem.
73
155-161
1977
Phaseolus vulgaris
Tulsiani, D.R.P.; Opheim, D.J.; Touster, O.
Purification and characterization of alpha-D-mannosidase from rat liver golgi membranes
J. Biol. Chem.
252
3227-3233
1977
Rattus sp.
Wallace, R.R.; Lewis, M.H.R.
alpha-D-Mannosidases in rat skeletal muscle
Biochem. Soc. Trans.
5
231-233
1977
Rattus sp.
Shepherd, V.; Montgomery, R.
alpha-D-Mannosidase. Preparation and properties of free and insolubilized enzyme
Biochim. Biophys. Acta
429
884-894
1976
Canavalia ensiformis
Hultberg, B.; Masson, P.K.; Sjbald, S.
Neutral alpha-mannosidase activity in human serum
Biochim. Biophys. Acta
445
398-405
1976
Homo sapiens
Shoup, V.A.; Touster, O.
Purification and characterization of the alpha-D-mannosidase of rat liver cytosol
J. Biol. Chem.
251
3845-3852
1976
Rattus sp.
Snaith, S.M.
Characterization of jack-bean alpha-D-mannosidase as a zinc metalloenzyme
Biochem. J.
147
83-90
1975
Canavalia ensiformis
Kaya, T.; Shibano, M.; Kutsumi, T.
Isolation and characterization of alpha-D-mannosidase from baker's yeast
J. Biochem.
73
181-182
1973
Saccharomyces cerevisiae
Matta, K.L.; Bahl, O.P.
Glycosidases of Aspergillus niger. IV. Purification and characterization of alpha-mannosidase
J. Biol. Chem.
247
1780-1787
1972
Aspergillus niger
Swaminathan, N.; Matta, K.L.; Donoso, L.A.; Bahl, O.P.
Glycosidases of Aspergillus niger. III. Purification and characterization of 1,2-alpha-mannosidase
J. Biol. Chem.
247
1775-1779
1972
Aspergillus niger
Okumura, T.; Yamashina, I.
Purification of alpha-mannosidase from hog kidney and its action on glycopeptides
J. Biochem.
68
561-571
1970
Sus scrofa
Ram, D.; Tulsiani, P.; Touster, O.
alpha-D-Mannosidase from golgi membranes of rat liver
Methods Enzymol.
50
500-505
1978
Rattus sp.
Mathur R.; Balasubramanian, A.S.
Cobalt-ion chelate affinity chromatography for the purification of brain neutral alpha-D-mannosidase and its separation from acid alpha-D-mannosidase
Biochem. J.
222
261-264
1984
Macaca radiata
Muramatsu, T.; Egami, F.
alpha-Mannosidase and beta-mannosidase from the liver of Turbo cortunus: Purification, properties and application in carbohydrate research
J. Biochem.
62
700-709
1967
Turbo cornutus
Li, Y.T.
Presence of alpha-D-mannosidic linkage in glycoproteins
J. Biol. Chem.
241
1010-1012
1966
Canavalia ensiformis
Amano, J.; Kobata, A.
Purification and characterization of a novel alpha-mannosidase from Aspergillus saitoi
J. Biochem.
99
1645-1654
1986
Aspergillus phoenicis
Tanimoto, K.; Nishimoto, T.; Saitoh, F.; Yamaguchi, H.
Improved purification of Aspergillus oryzae 1,2-alpha-mannosidase by using mannan gel affinity chromatography
J. Biochem.
99
601-604
1986
Aspergillus oryzae
Schutzbach, J.S.; Forsee, W.T.
Calcium ion activation of rabbit liver alpha 1,2-mannosidase
J. Biol. Chem.
265
2546-2549
1990
Oryctolagus cuniculus
Wongvithoonyaporn, P.; Bucke, C.; Svasti, J.
Separation, characterization, and specificity of a-mannosidases from Vigna umbellata
Biosci. Biotechnol. Biochem.
62
613-621
1998
Vigna umbellata
Numao, S.; Kuntz, D.A.; Withers, S.G.; Rose, D.R.
Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates
J. Biol. Chem.
278
48074-48083
2003
Drosophila melanogaster
Kawar, Z.; Karaveg, K.; Moremen, K.W.; Jarvis, D.L.
Insect cells encode a class II alpha-mannosidase with unique properties
J. Biol. Chem.
276
16335-16340
2001
Spodoptera frugiperda
Desmet, T.; Nerinckx, W.; Stals, I.; Callewaert, N.; Contreras, R.; Claeyssens, M.
Novel tools for the study of class I alpha-mannosidases: a chromogenic substrate and a substrate-analog inhibitor
Anal. Biochem.
307
361-367
2002
Trichoderma reesei
Nakajima, M.; Imamura, H.; Shoun, H.; Wakagi, T.
Unique metal dependency of cytosolic alpha-mannosidase from Thermotoga maritima, a hyperthermophilic bacterium
Arch. Biochem. Biophys.
415
87-93
2003
Thermotoga maritima
Popowycz, F.; Gerber-Lemaire, S.; Demange, R.; Rodriguez-Garcia, E.; Asenjo, A.T.; Robina, I.; Vogel, P.
Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors
Bioorg. Med. Chem. Lett.
11
2489-2493
2001
Canavalia ensiformis, Prunus dulcis
Nishio, T.; Hoshino, S.; Kondo, A.; Ogawa, M.; Matsuishi, Y.; Kitagawa, M.; Kawachi, R.; Oku, T.
alpha-Mannosidase-catalyzed synthesis of a (1->2)-alpha-D-rhamnodisaccharide derivative
Carbohydr. Res.
339
1389-1393
2004
Canavalia ensiformis
van den Elsen, J.M.; Kuntz, D.A.; Rose, D.R.
Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells
EMBO J.
20
3008-3017
2001
Drosophila sp. (in: flies)
Mora-Montes, H.M.; Lopez-Romero, E.; Zinker, S.; Ponce-Noyola, P.; Flores-Carreon, A.
Hydrolysis of Man9GlcNAc2 and Man8GlcNAc2 oligosaccharides by a purified alpha-mannosidase from Candida albicans
Glycobiology
14
593-598
2004
Candida albicans
Yamagishi, M.; Ishimizu, T.; Natsuka, S.; Hase, S.
Co(II)-regulated substrate specificity of cytosolic alpha-mannosidase
J. Biochem.
132
253-256
2002
Gallus gallus
Heikinheimo, P.; Helland, R.; Leiros, H.K.; Leiros, I.; Karlsen, S.; Evjen, G.; Ravelli, R.; Schoehn, G.; Ruigrok, R.; Tollersrud, O.K.; McSweeney, S.; Hough, E.
The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation
J. Mol. Biol.
327
631-644
2003
Bos taurus (Q29451), Bos taurus
Orlacchio, A.; Bernardi, G.; Orlacchio, A.; Emiliani, C.
alpha-D-Mannosidase properties in serum of patients with amyotrophic lateral sclerosis
J. Neurol.
248
1090-1092
2001
Homo sapiens
Berg, T.; King, B.; Meikle, P.J.; Nilssen, O.; Tollersrud, O.K.; Hopwood, J.J.
Purification and characterization of recombinant human lysosomal alpha-mannosidase
Mol. Genet. Metab.
73
18-29
2001
Homo sapiens
Kishimoto, T.; Hori, H.; Takano, D.; Nakano, Y.; Watanabe, M.; Mitsui, T.
Rice alpha-mannosidase digesting the high mannose glycopeptide of glutelin
Physiol. Plant.
112
15-24
2001
Oryza sativa
Nakajima, M.; Fushinobu, S.; Imamura, H.; Shoun, H.; Wakagi, T.
Crystallization and preliminary X-ray analysis of cytosolic alpha-mannosidase from Thermotoga maritima
Acta Crystallogr. Sect. F
62
104-105
2006
Thermotoga maritima
Siriwardena, A.; Strachan, H.; El-Daher, S.; Way, G.; Winchester, B.; Glushka, J.; Moremen, K.; Boons, G.
Potent and selective inhibition of class II alpha-D-mannosidase activity by a bicyclic sulfonium salt
ChemBioChem
6
845-848
2005
Homo sapiens
Faid, V.; Evjen, G.; Tollersrud, O.K.; Michalski, J.C.; Morelle, W.
Site-specific glycosylation analysis of the bovine lysosomal alpha-mannosidase
Glycobiology
16
440-461
2006
Bos taurus
Tempel, W.; Karaveg, K.; Liu, Z.J.; Rose, J.; Wang, B.C.; Moremen, K.W.
Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases
J. Biol. Chem.
279
29774-29786
2004
Mus musculus
Fiaux, H.; Popowycz, F.; Favre, S.; Schuetz, C.; Vogel, P.; Gerber-Lemaire, S.; Juillerat-Jeanneret, L.
Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells
J. Med. Chem.
48
4237-4246
2005
Canavalia ensiformis, Homo sapiens
Suzuki, T.; Hara, I.; Nakano, M.; Shigeta, M.; Nakagawa, T.; Kondo, A.; Funakoshi, Y.; Taniguchi, N.
Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol
Biochem. J.
400
33-41
2006
Homo sapiens (Q9NTJ4), Homo sapiens
Kestwal, R.M.; Konozy, E.H.; Hsiao, C.D.; Roque-Barreira, M.C.; Bhide, S.V.
Characterization of alpha-mannosidase from Erythrina indica seeds and influence of endogenous lectin on its activity
Biochim. Biophys. Acta
1770
24-28
2007
Erythrina variegata
Sivapriya, K.; Hariharaputran, S.; Suhas, V.L.; Chandra, N.; Chandrasekaran, S.
Conformationally locked thiosugars as potent alpha-mannosidase inhibitors: synthesis, biochemical and docking studies
Bioorg. Med. Chem.
15
5659-5665
2007
Homo sapiens
Pittis, M.G.; Montalvo, A.L.; Heikinheimo, P.; Sbaragli, M.; Balducci, C.; Persichetti, E.; Van Maldergem, L.; Filocamo, M.; Bembi, B.; Beccari, T.
Funtional characterization of four novel MAN2B1 mutations causing juvenile onset alpha-mannosidosis
Clin. Chim. Acta
375
136-139
2007
Homo sapiens (O00754), Homo sapiens
Jacobson, R.L.; Studentsky, L.; Schlein, Y.
Glycolytic and chitinolytic activities of Phlebotomus papatasi (Diptera: Psychodidae) from diverse ecological habitats
Folia Parasitol.
54
301-309
2007
Phlebotomus papatasi
Angelov, A.; Putyrski, M.; Liebl, W.
Molecular and biochemical characterization of alpha-glucosidase and alpha-mannosidase and their clustered genes from the thermoacidophilic archaeon Picrophilus torridus
J. Bacteriol.
188
7123-7131
2006
Picrophilus torridus (Q6L2X5), Picrophilus torridus
Racanicchi, L.; Montanucci, P.; Basta, G.P.; Pensato, A.; Conti, V.; Calafiore, R.
Effect of all trans retinoic acid on lysosomal alpha-D-mannosidase activity in Hl-60 cell: correlation with Hl-60 cells differentiation
Mol. Cell. Biochem.
308
17-24
2008
Homo sapiens
Kuntz, D.A.; Tarling, C.A.; Withers, S.G.; Rose, D.R.
Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen
Biochemistry
47
10058-10068
2008
Drosophila melanogaster
Fiaux, H.; Kuntz, D.A.; Hoffman, D.; Janzer, R.C.; Gerber-Lemaire, S.; Rose, D.R.; Juillerat-Jeanneret, L.
Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: optimizing the fit to the active site
Bioorg. Med. Chem.
16
7337-7346
2008
Homo sapiens, Canavalia sp.
Hossain, M.A.; Nakamura, K.; Kimura, Y.
alpha-mannosidase involved in turnover of plant complex type N-glycans in tomato (Lycopersicum esculentum) fruits
Biosci. Biotechnol. Biochem.
73
140-146
2009
Solanum lycopersicum
Shashidhara, K.S.; Gaikwad, S.M.
Class II alpha-mannosidase from Aspergillus fischeri: energetics of catalysis and inhibition
Int. J. Biol. Macromol.
44
112-115
2009
Aspergillus fischeri
Parnetti, L.; Balducci, C.; Pierguidi, L.; De Carlo, C.; Peducci, M.; DAmore, C.; Padiglioni, C.; Mastrocola, S.; Persichetti, E.; Paciotti, S.; Bellomo, G.; Tambasco, N.; Rossi, A.; Beccari, T.; Calabresi, P.
Cerebrospinal fluid beta-glucocerebrosidase activity is reduced in dementia with Lewy Bodies
Neurobiol. Dis.
34
484-486
2009
Homo sapiens
Miyake, K.; Nagai, K.
Inhibition of alpha-mannosidase attenuates endoplasmic reticulum stress-induced neuronal cell death
Neurotoxicology
30
144-150
2009
Mus musculus, Rattus norvegicus
Boone, M.A.; McDonald, F.E.; Lichter, J.; Lutz, S.; Cao, R.; Hardcastle, K.I.
1,5-Alpha-D-mannoseptanosides, ring-size isomers that are impervious to alpha-mannosidase-catalyzed hydrolysis
Org. Lett.
11
851-854
2009
Canavalia ensiformis
Dzugan, M.; Ksiazkiewicz, J.
Activity of alpha- and beta-mannosidases in semen and reproductive organs of the drake
Reprod. Biol.
9
25-37
2009
Anas sp.
Zhou, J.; Lin, C.Z.; Zheng, X.Z.; Lin, X.J.; Sang, W.J.; Wang, S.H.; Wang, Z.H.; Ebbole, D.; Lu, G.D.
Functional analysis of an alpha-1,2-mannosidase from Magnaporthe oryzae
Curr. Genet.
55
485-496
2009
Pyricularia oryzae, Pyricularia oryzae Guy11
Suits, M.D.; Zhu, Y.; Taylor, E.J.; Walton, J.; Zechel, D.L.; Gilbert, H.J.; Davies, G.J.
Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidase
PLoS ONE
5
e9006
2010
Streptococcus pyogenes M1 GAS (Q99YP5)
Cobucci-Ponzano, B.; Conte, F.; Strazzulli, A.; Capasso, C.; Fiume, I.; Pocsfalvi, G.; Rossi, M.; Moracci, M.
The molecular characterization of a novel GH38 alpha-mannosidase from the crenarchaeon Sulfolobus solfataricus revealed its ability in de-mannosylating glycoproteins
Biochimie
92
1895-1907
2010
Saccharolobus solfataricus (Q97UK5), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97UK5)
Hossain, M.A.; Nakano, R.; Nakamura, K.; Hossain, M.T.; Kimura, Y.
Molecular characterization of plant acidic alpha-mannosidase, a member of glycosylhydrolase family 38, involved in the turnover of N-glycans during tomato fruit ripening
J. Biochem.
148
603-616
2010
Solanum lycopersicum
Gregg, K.J.; Zandberg, W.F.; Hehemann, J.H.; Whitworth, G.E.; Deng, L.; Vocadlo, D.J.; Boraston, A.B.
Analysis of a new family of widely distributed metal-independent alpha-mannosidases provides unique insight into the processing of N-linked glycans
J. Biol. Chem.
286
15586-15596
2011
Clostridium perfringens, Streptococcus pneumoniae
Ghosh, S.; Meli, V.S.; Kumar, A.; Thakur, A.; Chakraborty, N.; Chakraborty, S.; Datta, A.
The N-glycan processing enzymes alpha-mannosidase and beta-D-N-acetylhexosaminidase are involved in ripening-associated softening in the non-climacteric fruits of capsicum
J. Exp. Bot.
62
571-582
2011
Capsicum annuum
Gnanesh Kumar, B.S.; Pohlentz, G.; Mormann, M.; Siva Kumar, N.
Characterization of a-mannosidase from Dolichos lablab seeds: Partial amino acid sequencing and N-glycan analysis
Protein Expr. Purif.
89
7-15
2013
Lablab purpureus
Nielsen, J.W.; Poulsen, N.R.; Johnsson, A.; Winther, J.R.; Stipp, S.L.; Willemoes, M.
Metal-ion dependent catalytic properties of Sulfolobus solfataricus class ii alpha-mannosidase
Biochemistry
51
8039-8046
2012
Saccharolobus solfataricus (Q97UK5), Saccharolobus solfataricus P2 (Q97UK5)
Koerdt, A.; Jachlewski, S.; Ghosh, A.; Wingender, J.; Siebers, B.; Albers, S.V.
Complementation of Sulfolobus solfataricus PBL2025 with an alpha-mannosidase: effects on surface attachment and biofilm formation
Extremophiles
16
115-125
2012
Saccharolobus solfataricus (Q97UK5), Saccharolobus solfataricus P2 (Q97UK5)
Kashyap, V.; Sharma, S.; Singh, V.; Sharma, S.K.; Saquib, M.; Srivastava, R.; Shaw, A.K.
Deoxysugars as antituberculars and alpha-mannosidase inhibitors
Antimicrob. Agents Chemother.
58
3530-3532
2014
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Hansen, D.K.; Webb, H.; Nielsen, J.W.; Harris, P.; Winther, J.R.; Willemoes, M.
Mutational analysis of divalent metal ion binding in the active site of class II alpha-mannosidase from Sulfolobus solfataricus
Biochemistry
24
2032-2039
2015
Saccharolobus solfataricus (Q97UK5), Saccharolobus solfataricus P2 (Q97UK5)
Riise Stensland, H.; Klenow, H.; Nguyen, L.; Hansen, G.; Malm, D.; Nilssen, .
Identification of 83 novel alpha-mannosidosis-associated sequence variants: Functional analysis of MAN2B1 missense mutations
Hum. Mutat.
33
511-520
2012
Homo sapiens (O00754), Homo sapiens
Borgwardt, L.; Dali, C.I.; Fogh, J.; Mansson, J.E.; Olsen, K.J.; Beck, H.C.; Nielsen, K.G.; Nielsen, L.H.; Olsen, S.O.; Riise Stensland, H.M.; Nilssen, O.; Wibrand, F.; Thuesen, A.M.; Pearl, T.; Haugsted, U.; Saftig, P.; Blanz, J.; Jones, S.A.; Tylki-Szymanska, A.; Guffon-Fouiloux, N.; Beck, M.; Lund, A.M.
Enzyme replacement therapy for alpha-mannosidosis: 12 months follow-up of a single centre, randomised, multiple dose study
J. Inherit. Metab. Dis.
36
1015-1024
2013
Homo sapiens
Retamal, C.A.; Dias, A.J.; Brasil, F.C.; Lanzana, F.R.; Lopez, M.L.
Alpha-mannosidase activity in stallion epididymal fluid and spermatozoa
Theriogenology
78
252-262
2012
Equus caballus
Shah, P.; Saquib, M.; Sharma, S.; Husain, I.; Sharma, S.K.; Singh, V.; Srivastava, R.; Shaw, A.K.; Siddiqi, M.I.
3D-QSAR and molecular modeling studies on 2,3-dideoxy hexenopyranosid-4-uloses as anti-tubercular agents targeting alpha-mannosidase
Bioorg. Chem.
59
91-96
2015
Mycobacterium tuberculosis (P96937), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P96937)
Paciotti, S.; Codini, M.; Tasegian, A.; Ceccarini, M.R.; Cataldi, S.; Arcuri, C.; Fioretti, B.; Albi, E.; Beccari, T.
Lysosomal alpha-mannosidase and alpha-mannosidosis
Front. Biosci.
22
157-167
2017
Homo sapiens (O00754), Homo sapiens
Lund, A.M.; Borgwardt, L.; Cattaneo, F.; Ardigo, D.; Geraci, S.; Gil-Campos, M.; De Meirleir, L.; Laroche, C.; Dolhem, P.; Cole, D.; Tylki-Szymanska, A.; Lopez-Rodriguez, M.; Guillen-Navarro, E.; Dali, C.I.; Heron, B.; Fogh, J.; Muschol, N.; Phillips, D.; Van den Hout, J.M.H.; Jones, S.A.; Amraoui, Y.
Comprehensive long-term efficacy and safety of recombinant human alpha-mannosidase (velmanase alfa) treatment in patients with alpha-mannosidosis
J. Inherit. Metab. Dis.
41
1225-1233
2018
Homo sapiens
Harmatz, P.; Cattaneo, F.; Ardigo, D.; Geraci, S.; Hennermann, J.B.; Guffon, N.; Lund, A.; Hendriksz, C.J.; Borgwardt, L.
Enzyme replacement therapy with velmanase alfa (human recombinant alpha-mannosidase) Novel global treatment response model and outcomes in patients with alpha-mannosidosis
Mol. Genet. Metab.
124
152-160
2018
Homo sapiens
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