Crystallization (Comment) | Organism |
---|---|
structual 3D analysis | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
DELTAT887 | T887SfsX45, c.2660delC causes a frameshift introducing a premature stop codon (p.T887SfsX45) | Homo sapiens |
H200N | missense mutantion c.597 C>A. Equal deleterious effect missense mutations indicating disease-causing mutations | Homo sapiens |
L518P | missense mutantion c.1553 THomo sapiens |
|
R916S | missense mutantion c.2746 C>A, spatially close to the oldest known inherited alpha mannosidosis mutation p.R750W. Equal deleterious effect missense mutations indicating disease-causing mutations | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
120000 | - |
LAMAN 120 kDa precursor detected in wild type and mutant constructs. Western blot analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00754 | MA2B1_HUMAN | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl-alpha-D-mannopyranoside | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha-mannosidase | acidic exoglycosidase, belonging to glycosylhydrolase family 38 | Homo sapiens |
Laman | - |
Homo sapiens |
lysosomal alpha-mannosidase | - |
Homo sapiens |