1.14.11.68: [histone H3]-trimethyl-L-lysine27 demethylase

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For detailed information about [histone H3]-trimethyl-L-lysine27 demethylase, go to the full flat file.

Word Map on EC 1.14.11.68

1.14.11.68

kabuki

chromatin

facial

demethylases

intellectual

pik3ca

arid1a

crebbp

h3k4me3

polycomb

medicine

muscle-invasive

smarca4

k-specific

fat1

gestalt

gsk-j4

Reaction

a [histone H3]-N6,N6,N6-trimethyl-L-lysine27

+ 2 2-oxoglutarate + 2 O2 =

+ 2 succinate + 2 formaldehyde + 2 CO2

Synonyms

F18E9.5, histone demethylase, jmjd-3.1, JMJD3, KDM6A, Kdm6al, KDM6B, KDM6C, lysine-specific demethylase 6A, lysine-specific demethylase 6B, UTX, UTX1, UTY

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

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Results	in table
22	AA Sequence
8	Application
2	Cloned(Commentary)
1	Crystallization (Commentary)
585	Disease/ Diagnostics
5	Expression
23	General Information
4	Inhibitors
10	Localization
1	Metals/Ions
5	Natural Substrates/ Products (Substrates)
35	Organism
2	Protein Variants
3	Reaction
33	Reference
24	Source Tissue
23	Substrates and Products (Substrate)
32	Synonyms
1	Systematic Name

Organism

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Organism on EC 1.14.11.68 - [histone H3]-trimethyl-L-lysine27 demethylase

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Caenorhabditis elegans

UniProt

isoform Utx1

UniProt

isoform Kdm6a

UniProt

isoform Jmjd3

UniProt