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1.14.11.68: [histone H3]-trimethyl-L-lysine27 demethylase

This is an abbreviated version!
For detailed information about [histone H3]-trimethyl-L-lysine27 demethylase, go to the full flat file.

Word Map on EC 1.14.11.68

Reaction

a [histone H3]-N6,N6,N6-trimethyl-L-lysine27
+ 2 2-oxoglutarate + 2 O2 =
a [histone H3]-N6-methyl-L-lysine27
+ 2 succinate + 2 formaldehyde + 2 CO2

Synonyms

F18E9.5, histone demethylase, jmjd-3.1, JMJD3, KDM6A, Kdm6al, KDM6B, KDM6C, lysine-specific demethylase 6A, lysine-specific demethylase 6B, UTX, UTX1, UTY

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase

Sequence

Sequence on EC 1.14.11.68 - [histone H3]-trimethyl-L-lysine27 demethylase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
JMJ30_ARATH
429
0
48075
Swiss-Prot
other Location (Reliability: 3)
JMJ32_ARATH
345
0
39123
Swiss-Prot
other Location (Reliability: 2)
JM705_ORYSJ
1286
0
142049
Swiss-Prot
other Location (Reliability: 5)
KDM6A_HUMAN
1401
0
154177
Swiss-Prot
Secretory Pathway (Reliability: 5)
KDM6A_MOUSE
1401
0
154355
Swiss-Prot
Secretory Pathway (Reliability: 3)
KDM6B_HUMAN
1643
0
176632
Swiss-Prot
Mitochondrion (Reliability: 5)
KDM6B_MOUSE
1641
0
176355
Swiss-Prot
Mitochondrion (Reliability: 5)
UTY_HUMAN
1347
1
149548
Swiss-Prot
other Location (Reliability: 3)
UTY_MOUSE
1212
0
136737
Swiss-Prot
other Location (Reliability: 1)
UTY_PANTR
1079
1
118032
Swiss-Prot
other Location (Reliability: 2)
A0A812E8H1_SEPPH
1641
9
185730
TrEMBL
other Location (Reliability: 2)
A0A7R8D4Q1_LEPSM
259
0
29723
TrEMBL
other Location (Reliability: 2)
A0A6J8AMD0_MYTCO
1228
0
138418
TrEMBL
Secretory Pathway (Reliability: 4)
A0A7R8D579_LEPSM
108
0
12514
TrEMBL
other Location (Reliability: 3)
A0A6J8AQW2_MYTCO
1297
0
145932
TrEMBL
Secretory Pathway (Reliability: 4)
A0A6J8AQZ1_MYTCO
1274
0
143428
TrEMBL
Secretory Pathway (Reliability: 4)
A0A7R8D4P8_LEPSM
1183
0
132724
TrEMBL
other Location (Reliability: 2)
A0A812EA49_SEPPH
1640
9
185601
TrEMBL
other Location (Reliability: 2)
A0A0G2K6D0_RAT
1316
0
144709
TrEMBL
-
A1L1S9_DANRE
1311
0
143724
TrEMBL
-
K9K8P2_XENTR
1739
0
193362
TrEMBL
other Location (Reliability: 1)
JMJ31_CAEEL
1061
0
120302
Swiss-Prot
-