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Literature summary for 1.14.11.68 extracted from

  • Guo, X.; Zhang, Y.; Zhang, Q.; Fa, P.; Gui, Y.; Gao, G.; Cai, Z.
    The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells (2016), Toxicol. Ind. Health, 32, 1286-92 .
    View publication on PubMed
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Application

Application Comment Organism
medicine presence of nickel chloride upregulates the expression of H3K27me3 demethylase Jmjd3 in kidney cancer cells, which is accompanied by the reduction in the protein level of H3K27me3 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O15054
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Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
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 Homo sapiens
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kidney kidney cancer cell Homo sapiens
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Expression

Organism Comment Expression
Homo sapiens presence of nickel chloride upregulates the expression of H3K27me3 demethylase Jmjd3 in kidney cancer cells, which is accompanied by the reduction in the protein level of H3K27me3 up