1.14.11.68: [histone H3]-trimethyl-L-lysine27 demethylase
This is an abbreviated version!
For detailed information about [histone H3]-trimethyl-L-lysine27 demethylase, go to the full flat file.
Word Map on EC 1.14.11.68
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1.14.11.68
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kabuki
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chromatin
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facial
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demethylases
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intellectual
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pik3ca
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arid1a
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crebbp
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h3k4me3
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polycomb
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medicine
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muscle-invasive
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smarca4
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k-specific
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fat1
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gestalt
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gsk-j4
- 1.14.11.68
-
kabuki
- chromatin
-
facial
- demethylases
-
intellectual
- pik3ca
-
arid1a
- crebbp
-
h3k4me3
-
polycomb
- medicine
-
muscle-invasive
-
smarca4
-
k-specific
- fat1
-
gestalt
- gsk-j4
Reaction
+ 2 2-oxoglutarate + 2 O2 = + 2 succinate + 2 formaldehyde + 2 CO2
Synonyms
F18E9.5, histone demethylase, jmjd-3.1, JMJD3, KDM6A, Kdm6al, KDM6B, KDM6C, lysine-specific demethylase 6A, lysine-specific demethylase 6B, UTX, UTX1, UTY
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.14.11.68 - [histone H3]-trimethyl-L-lysine27 demethylase
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REACTION DIAGRAM
[histone H3]-N6,N6,N6-trimethyl-L-lysine 27 + 2-oxoglutarate + O2
[histone H3]-N6,N6-dimethyl-L-lysine 27 + succinate + formaldehyde + CO2
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[histone H3]-N6,N6,N6-trimethyllysine27 + 2 2-oxoglutarate + 2 O2
[histone H3]-N6-methyllysine27 + 2 succinate + 2 formaldehyde + 2 CO2
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[histone H3]-N6,N6,N6-trimethyllysine27 + 2-oxoglutarate + O2
[histone H3]-N6,N6-dimethyllysine27 + succinate + formaldehyde + CO2
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[histone H3]-N6,N6-dimethyl-L-lysine 27 + 2-oxoglutarate + O2
[histone H3]-N6-methyl-L-lysine 27 + succinate + formaldehyde + CO2
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?
[histone H3]-N6,N6-dimethyllysine27 + 2-oxoglutarate + O2
[histone H3]-N6-methyllysine27 + succinate + formaldehyde + CO2
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?