4.4.1.5: lactoylglutathione lyase
This is an abbreviated version!
For detailed information about lactoylglutathione lyase, go to the full flat file.
Word Map on EC 4.4.1.5
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4.4.1.5
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glycation
-
detoxify
-
gsh
-
dicarbonyls
-
erythrocyte
-
d-lactate
-
adduct
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dismutase
-
endproducts
-
rage
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s-transferase
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mellitus
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methylglyoxal-induced
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glyoxalases
-
byproduct
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hyperglycemia
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glutathione-dependent
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phosphoglucomutase
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metalloenzyme
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hemithioacetal
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mg-induced
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hla-a
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aldose
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3-deoxyglucosone
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enediolate
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d-lactic
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pentosidine
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cyclopentyl
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mdhar
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haptoglobin
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aminoguanidine
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diesters
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monodehydroascorbate
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6-phosphogluconate
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anti-glycation
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dehydroascorbate
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anxiety-like
-
gsh-dependent
-
pyridoxamine
-
analysis
-
trypanothione
-
medicine
-
drug development
- 4.4.1.5
-
glycation
-
detoxify
- gsh
-
dicarbonyls
- erythrocyte
- d-lactate
- adduct
- dismutase
-
endproducts
- rage
- s-transferase
- mellitus
-
methylglyoxal-induced
-
glyoxalases
-
byproduct
- hyperglycemia
-
glutathione-dependent
- phosphoglucomutase
-
metalloenzyme
- hemithioacetal
-
mg-induced
- hla-a
- aldose
- 3-deoxyglucosone
-
enediolate
-
d-lactic
-
pentosidine
-
cyclopentyl
- mdhar
- haptoglobin
- aminoguanidine
- diesters
- monodehydroascorbate
- 6-phosphogluconate
-
anti-glycation
- dehydroascorbate
-
anxiety-like
-
gsh-dependent
- pyridoxamine
- analysis
- trypanothione
- medicine
- drug development
Reaction
Synonyms
aldoketomutase, CLO GlxI, Glb33, GLI, GLO I, GLO-1, GLO-I, Glo1, GloA, GloA1, GloA2, GloA3, GloI, Glx I, Glx-I, Glx1, GLXI, Gly I, gly-I, GLY1, glyoxalase 1, glyoxalase I, glyoxalase-1, glyoxalase-I, glyoxylase I, GmGlyox I, ketone-aldehyde mutase, lactoylglutathione lyase, lactoylglutathione methylglyoxal lyase, LGL, lyase, lactoylglutathione, methylglyoxalase, methylglyoxylase, OsGLYI-11.2, PfGlx I, rhGLO I, S-D-lactoylglutathione methylglyoxal lyase, S-D-lactoylglutathione methylglyoxal lyase (isomerizing), S-D-lactoylglutathione:methylglyoxal lyase, SpGlo1, STM3117, YaiA
ECTree
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Molecular Weight
Molecular Weight on EC 4.4.1.5 - lactoylglutathione lyase
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14251
-
x * 14251, electrospray ionization mass spectrometry, x * 14251, calculated
14833
-
x * 14833, electrospray ionization mass spectrometry, x * 14834, calculated
14834
-
x * 14833, electrospray ionization mass spectrometry, x * 14834, calculated
15669
-
x * 15669, electrospray ionization mass spectrometry, x * 15669, calculated
15818
2 * 15818, His6-tagged enzyme, sequence calculation, the enzyme forms two active sites, each within single subunits
16000
16647
-
x * 17000, SDS-PAGE or Western blot analysis, x * 16647, predicted, x * 16650, MALDI-TOF-MS analysis
16650
-
x * 17000, SDS-PAGE or Western blot analysis, x * 16647, predicted, x * 16650, MALDI-TOF-MS analysis
17000
-
x * 17000, SDS-PAGE or Western blot analysis, x * 16647, predicted, x * 16650, MALDI-TOF-MS analysis
20647
-
2 * 20647, sequence calculation, 2 * 21000, recombinant enzyme, SDS-PAGE
20810
2 * 20810, calculated from sequence, MALDI-TOF mass spectrometry, SDS-PAGE
21000
23000
24000
25000
26000
27000
29000
33000
34000
36000
37000
38000
42000
43000
43310
calculated from sequence, 30fold upregulated protein spot in the 2D-electrophoresis, identified as glyoxalase I, the expression is regulated by the operon yahCD-yaiAB
44000
46000
48000
58000
60000
additional information
16000
-
Western blot analysis of whole cell lysate, equivalent to the predicted molecular mass
16000
-
Western blot analysis of whole cell lysate, equivalent to the predicted molecular mass. Recombinant protein containing a tetracycline-inducible pLew100-TcGLO1 construct, expression of GLO1 of Trypanosoma cruzi in Trypanosoma brucei, Western blot analysis
21000
-
2 * 20647, sequence calculation, 2 * 21000, recombinant enzyme, SDS-PAGE
-
GlxI is longer than the Escherichia coli enzyme but similar to the Homo sapiens enzyme
additional information
GlxI is longer than the Escherichia coli enzyme but similar to the Homo sapiens enzyme
additional information
GlxI is longer than the Escherichia coli enzyme but similar to the Homo sapiens enzyme
additional information
GlxI is longer than the Escherichia coli enzyme but similar to the Homo sapiens enzyme
additional information
-
size is similar to the Escherichia coli enzyme and to Pseudomonas aeruginose Glx1 GloA1
additional information
size is similar to the Escherichia coli enzyme and to Pseudomonas aeruginose Glx1 GloA1
additional information
size is similar to the Escherichia coli enzyme and to Pseudomonas aeruginose Glx1 GloA1
additional information
size is similar to the Escherichia coli enzyme and to Pseudomonas aeruginose Glx1 GloA1