EC Explorer
[browse EC tree] - [search]
EC 1.14.13.93 Details
show Brenda entryEC number
1.14.13.93
Accepted name
(+)-abscisic acid 8′-hydroxylase
Reaction
(+)-abscisate + NADPH + H+ + O2 = 8′-hydroxyabscisate + NADP+ + H2O
Other name(s)
(+)-ABA 8′-hydroxylase,
ABA 8′-hydroxylase
Systematic name
abscisate,NADPH:oxygen oxidoreductase (8′-hydroxylating)
CAS registry number
153190-37-5
Comment
A heme-thiolate protein (P-450). Catalyses the first step in the oxidative degradation of abscisic acid and is considered to be the pivotal enzyme in controlling the rate of degradation of this plant hormone [1]. CO inhibits the reaction, but its effects can be reversed by the presence of blue light [1]. The 8′-hydroxyabscisate formed can be converted into (–)-phaseic acid, most probably spontaneously. Other enzymes involved in the abscisic-acid biosynthesis pathway are EC 1.1.1.288 (xanthoxin dehydrogenase), EC 1.2.3.14 (abscisic-aldehyde oxidase) and EC 1.13.11.51 (9-cis-epoxycarotenoid dioxygenase).
History
created 2005, deleted 2018
back to topEC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.4.1 created 1961, deleted 2002 1.6.4.2 created 1961, modified 1989, deleted 2002 1.6.4.3 created 1961, modified 1976, deleted 1983 1.6.4.4 created 1965, deleted 2002 1.6.4.5 created 1972, deleted 2002 1.6.4.6 created 1972, deleted 2002 1.6.4.7 created 1978, deleted 2002 1.6.4.8 created 1989, deleted 2002 1.6.4.9 created 1992, deleted 2002 1.6.4.10 created 1992, deleted 2002 1.14.13.45 created 1992, deleted 2003
