2.1.2.1: glycine hydroxymethyltransferase
This is an abbreviated version!
For detailed information about glycine hydroxymethyltransferase, go to the full flat file.
Word Map on EC 2.1.2.1
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2.1.2.1
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one-carbon
-
pyridoxal
-
thymidylate
-
purine
-
5'-phosphate
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homocysteine
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dihydrofolate
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folate-dependent
-
photorespiratory
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photorespiration
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folate-mediated
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pyridoxal-5'-phosphate
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thf
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dtmp
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mthfd1
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plp-dependent
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remethylation
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aldimine
-
phgdh
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medicine
-
folate-metabolizing
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5,10-methenyltetrahydrofolate
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5'-phosphate-dependent
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antifolate
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hydroxypyruvate
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quinonoid
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5-methyltetrahydrofolate
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glycerate
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5-formyltetrahydrofolate
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drug development
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folate-related
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d-alanine
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c1-tetrahydrofolate
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1-carbon
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5-formyl
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polyglutamate
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l-threonine
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alpha-protons
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slc19a1
-
retro-aldol
-
degradation
-
analysis
-
synthesis
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biotechnology
-
pharmacology
- 2.1.2.1
-
one-carbon
- pyridoxal
- thymidylate
- purine
- 5'-phosphate
- homocysteine
- dihydrofolate
-
folate-dependent
-
photorespiratory
-
photorespiration
-
folate-mediated
- pyridoxal-5'-phosphate
- thf
- dtmp
- mthfd1
-
plp-dependent
-
remethylation
-
aldimine
- phgdh
- medicine
-
folate-metabolizing
- 5,10-methenyltetrahydrofolate
-
5'-phosphate-dependent
- antifolate
- hydroxypyruvate
-
quinonoid
- 5-methyltetrahydrofolate
- glycerate
- 5-formyltetrahydrofolate
- drug development
-
folate-related
- d-alanine
-
c1-tetrahydrofolate
-
1-carbon
-
5-formyl
- polyglutamate
- l-threonine
-
alpha-protons
-
slc19a1
-
retro-aldol
- degradation
- analysis
- synthesis
- biotechnology
- pharmacology
Reaction
Synonyms
AtSHMT3, bsSHMT, bstSHMT, EC 4.1.2.6, eSHMT, GlyA, GlyA protein, glycine hydroxymethyltransferrase, hSHMT, L-serine hydroxymethyltransferase, mitochondrial serine hydroxymethyltransferase, MJ1597, PvSHMT, Rhg4, serine hydroxymethyl transferase, serine hydroxymethylase hydroxymethyltransferase, serine, serine hydroxymethyltransferase, serine hydroxymethyltransferase 1, serine hydroxymethyltransferase 2, serine hydroxymethyltransferase 2alpha, serine transhydroxymethylase, serine:H4F hydroxymethyltransferase, serine:tetrahydrofolate hydroxymethyltransferase, SHM1, SHM2, SHMT, SHMT-1, SHMT-L, SHMT-S, SHMT08, SHMT1, SHMT2, SHMT2alpha, SHMT3, zcSHMT, zebrafish cytosolic serine hydroxymethyltransferase, zebrafish mitochondiral serine hydroxymethyltransferase, zmSHMT
ECTree
2.1.2.1 glycine hydroxymethyltransferaseAdvanced search results
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results (Turnover Number
Turnover Number on EC 2.1.2.1 - glycine hydroxymethyltransferase
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TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.246
D-serine
-
apparent value, in 50 mM HEPES, pH 8.0 containing 0.5 mM EDTA, 1 mM dithiothreitol, at 25°C
4.8
DL-3-phenylserine
mutant enzyme I249L, at pH 7.8 and 30°C
6.7
L-serine
mutant enzyme L276A, at 20°C in 50 mM Na-HEPES (pH 7.2), containing 0.2 mM dithiothreitol and 0.1 mM EDTA
6.7
L-serine
mutant enzyme L85A/L276A, at 20°C in 50 mM Na-HEPES (pH 7.2), containing 0.2 mM dithiothreitol and 0.1 mM EDTA
10.8
L-serine
mutant enzyme L85A, at 20°C in 50 mM Na-HEPES (pH 7.2), containing 0.2 mM dithiothreitol and 0.1 mM EDTA
11.4
L-serine
wild type enzyme, at 20°C in 50 mM Na-HEPES (pH 7.2), containing 0.2 mM dithiothreitol and 0.1 mM EDTA
640
L-serine
-
wild-type enzyme, pH and temperature not specified in the publication
0.033
tetrahydrofolate
mutant L474F, in the presence of pyridoxal phosphate
0.045
tetrahydrofolate
mutant S394N, in the presence of pyridoxal phosphate
0.07
tetrahydrofolate
wild-type, in the presence of pyridoxal phosphate
0.41
tetrahydrofolate
-
at pH 8.3, temperature not specified in the publication
0.57
tetrahydrofolate
-
at pH 7.9, temperature not specified in the publication
0.81
tetrahydrofolate
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at pH 7.5, temperature not specified in the publication
1.1
tetrahydrofolate
-
at pH 6.6, temperature not specified in the publication
1.13
tetrahydrofolate
-
mutant K251R, in the presence of 0.25 mM pyridoxal phosphate
1.3
tetrahydrofolate
-
wild-type, in the presence of 0.25 mM pyridoxal phosphate
1.41
tetrahydrofolate
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at pH 7.1, temperature not specified in the publication
15.8
tetrahydrofolate
pH 8.5, temperature not specified in the publication, recombinant AtSHMT3
