2.1.2.1: glycine hydroxymethyltransferase
This is an abbreviated version!
For detailed information about glycine hydroxymethyltransferase, go to the full flat file.
Word Map on EC 2.1.2.1
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2.1.2.1
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one-carbon
-
pyridoxal
-
thymidylate
-
purine
-
5'-phosphate
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homocysteine
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dihydrofolate
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folate-dependent
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photorespiratory
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photorespiration
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folate-mediated
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pyridoxal-5'-phosphate
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thf
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dtmp
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mthfd1
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plp-dependent
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remethylation
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aldimine
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phgdh
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medicine
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folate-metabolizing
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5,10-methenyltetrahydrofolate
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5'-phosphate-dependent
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antifolate
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hydroxypyruvate
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quinonoid
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5-methyltetrahydrofolate
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glycerate
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5-formyltetrahydrofolate
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drug development
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folate-related
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d-alanine
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c1-tetrahydrofolate
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1-carbon
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5-formyl
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polyglutamate
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l-threonine
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alpha-protons
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slc19a1
-
retro-aldol
-
degradation
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analysis
-
synthesis
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biotechnology
-
pharmacology
- 2.1.2.1
-
one-carbon
- pyridoxal
- thymidylate
- purine
- 5'-phosphate
- homocysteine
- dihydrofolate
-
folate-dependent
-
photorespiratory
-
photorespiration
-
folate-mediated
- pyridoxal-5'-phosphate
- thf
- dtmp
- mthfd1
-
plp-dependent
-
remethylation
-
aldimine
- phgdh
- medicine
-
folate-metabolizing
- 5,10-methenyltetrahydrofolate
-
5'-phosphate-dependent
- antifolate
- hydroxypyruvate
-
quinonoid
- 5-methyltetrahydrofolate
- glycerate
- 5-formyltetrahydrofolate
- drug development
-
folate-related
- d-alanine
-
c1-tetrahydrofolate
-
1-carbon
-
5-formyl
- polyglutamate
- l-threonine
-
alpha-protons
-
slc19a1
-
retro-aldol
- degradation
- analysis
- synthesis
- biotechnology
- pharmacology
Reaction
Synonyms
AtSHMT3, bsSHMT, bstSHMT, EC 4.1.2.6, eSHMT, GlyA, GlyA protein, glycine hydroxymethyltransferrase, hSHMT, L-serine hydroxymethyltransferase, mitochondrial serine hydroxymethyltransferase, MJ1597, PvSHMT, Rhg4, serine hydroxymethyl transferase, serine hydroxymethylase hydroxymethyltransferase, serine, serine hydroxymethyltransferase, serine hydroxymethyltransferase 1, serine hydroxymethyltransferase 2, serine hydroxymethyltransferase 2alpha, serine transhydroxymethylase, serine:H4F hydroxymethyltransferase, serine:tetrahydrofolate hydroxymethyltransferase, SHM1, SHM2, SHMT, SHMT-1, SHMT-L, SHMT-S, SHMT08, SHMT1, SHMT2, SHMT2alpha, SHMT3, zcSHMT, zebrafish cytosolic serine hydroxymethyltransferase, zebrafish mitochondiral serine hydroxymethyltransferase, zmSHMT
ECTree
2.1.2.1 glycine hydroxymethyltransferaseAdvanced search results
results (
results (Molecular Weight
Molecular Weight on EC 2.1.2.1 - glycine hydroxymethyltransferase
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MOLECULAR WEIGHT 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
180000 - 200000
200000
200000 - 204000
-
mitochondria, gel filtration, PAGE, amino acid composition
210000
215000
216000
220000
230000
25000
-
refolded pyridoxal-5'-phosphate-binding domain of SHMT, gel filtration
44500
x * 44500, about, sequence calculation, x * 60000, recombinant GST-tagged enzyme, SDS-PAGE
45000
45050
2 * 45050, recombinant N-terminally His-tagged enzyme, mass spectrometry
50000
52020
4 * 52020, cytosolic isoform, sequence calculation, 4 * 53000, recombinant cytosolic isoform, SDS-PAGE
53000
54000
55000
60000
x * 44500, about, sequence calculation, x * 60000, recombinant GST-tagged enzyme, SDS-PAGE
90000
91000
98000
additional information
180000 - 200000
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gel filtration, sucrose density gradient centrifugation
53000
4 * 52020, cytosolic isoform, sequence calculation, 4 * 53000, recombinant cytosolic isoform, SDS-PAGE
91000
wild type SHMT exists as a dimer in both apo- and holo-forms, ultracentrifugation
