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EC 1.14.13.33 Details
show Brenda entryEC number
1.14.13.33
Accepted name
4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
Reaction
4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O
Other name(s)
4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate)),
4-hydroxybenzoate-3-hydroxylase,
4-hydroxybenzoate 3-hydroxylase
Systematic name
4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)
CAS registry number
95471-33-3
Comment
A flavoprotein (FAD). The enzyme from Corynebacterium cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2 4-hydroxybenzoate 3-monooxygenase). It is less specific for NADPH than EC 1.14.13.2.
History
created 1989, modified 1999
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.99.4 created 1965, deleted 1972 1.6.99.8 created 1972, deleted 2002 1.6.99.9 created 1972, deleted 2002 1.6.99.10 created 1978, deleted 1981 1.6.99.11 created 1989, deleted 2002 1.6.99.12 created 1989, deleted 2002 1.6.99.13 created 1992, deleted 2002 1.14.13.45 created 1992, deleted 2003
