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Information on EC 1.14.13.2 - 4-hydroxybenzoate 3-monooxygenase

for references in articles please use BRENDA:EC1.14.13.2

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IUBMB Comments

A flavoprotein (FAD). Most enzymes from Pseudomonas are highly specific for NADPH (cf. EC 1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
p-hydroxybenzoate hydroxylase, para-hydroxybenzoate hydroxylase, 4-hydroxybenzoate hydroxylase, 4-hydroxybenzoate 3-monooxygenase, 4-hydroxybenzoate 3-hydroxylase, m-hydroxybenzoate hydroxylase, 4hba 3-hydroxylase, 4-hba 3-monooxygenase, 4-hba 3-hydroxylase, phbad, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-hydroxybenzoate + NADPH + H+ + O2 = 3,4-dihydroxybenzoate + NADP+ + H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
4-chlorobenzoate degradation, 4-coumarate degradation (aerobic), 4-hydroxymandelate degradation, 4-methylphenol degradation to protocatechuate, bisphenol A degradation, polybrominated dihydroxylated diphenyl ethers biosynthesis, spongiadioxin C biosynthesis