Reference on EC 1.14.13.2 - 4-hydroxybenzoate 3-monooxygenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Whited, G.M.; Gibson, D.T.
Separation and partial characterization of the enzymes of the toluene-4-monooxygenase catabolic pathway in Pseudomonas mendocina KR1
J. Bacteriol.
173
3017-3020
1991
Pseudomonas mendocina, Pseudomonas mendocina KR1
Howell, L.G.; Spector, T.; Massey, V.
Purification and properties of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens
J. Biol. Chem.
247
4340-4350
1972
Pseudomonas fluorescens
Spector, T.; Massey, V.
Studies on the effector specificity of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens
J. Biol. Chem.
247
4679-4687
1972
Pseudomonas fluorescens
Spector, T.; Massey, V.
p-Hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Evidence for an oxygenated flavin intermediate
J. Biol. Chem.
247
5632-5636
1972
Pseudomonas fluorescens
Hosokawa, K.; Stanier, R.Y.
Crystallization and properties of p-hydroxybenzoate hydroxylase from Pseudomonas putida
J. Biol. Chem.
241
2453-2460
1966
Pseudomonas fluorescens
Steennis, P.J.; Cordes, M.M.; Hilkens, J.G.H.; Mueller, F.
On the interaction of para-hydroxybenzoate hydroxylase from Pseudomonas fluorescens with halogen ions
FEBS Lett.
36
177-180
1973
Pseudomonas fluorescens
Husain, M.; Schopfer, L.M.; Massey, V.
p-Hydroxybenzoate hydroxylase and melilotate hydroxylase
Methods Enzymol.
53
543-558
1978
Delftia acidovorans, Pseudomonas putida, Pseudomonas fluorescens, Pseudomonas putida A 3.12, Pseudomonas putida M-6
Shoun, H.; Arima, K.; Beppu, T.
Inhibition of p-hydroxybenzoate hydroxylase by anions: possible existence of two anion-binding sites in the site for reduced nicotinamide adenine dinucleotide phosphate
J. Biochem.
93
169-176
1983
Delftia acidovorans
Drenth, J.; Hol, W.G.J.; Wierenga, R.K.
Crystallization and preliminary x-ray investigation of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens
J. Biol. Chem.
250
5268-5269
1975
Pseudomonas fluorescens
Entsch, B.
Hydroxybenzoate hydroxylase
Methods Enzymol.
188
138-147
1990
Pseudomonas aeruginosa
van Berkel, W.J.H.; Mueller, F.
The temperature and pH dependence of some properties of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens
Eur. J. Biochem.
179
307-314
1989
Pseudomonas fluorescens
Entsch, B.; Ballou, D.P.
Purification, properties, and oxygen reactivity of p-hydroxybenzoate hydroxylase from Pseudomonas aeruginosa [published erratum appears in Biochim Biophys Acta 1990 Mar 29;1038(1):139]
Biochim. Biophys. Acta
999
313-322
1989
Pseudomonas aeruginosa
Entsch, B.; Ballou, D.P.; Massey, V.
Flavin-oxygen derivatives involved in hydroxylation by p-hydroxybenzoate hydroxylase
J. Biol. Chem.
251
2550-2563
1976
Pseudomonas fluorescens
van Berkel, W.J.H.; Mueller, F.
The elucidation of the microheterogeneity of highly purified p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens by various biochemical techniques
Eur. J. Biochem.
167
35-46
1987
Pseudomonas fluorescens
Shoun, H.; Beppu, T.; Arima, K.
An essential arginine residue at the substrate-binding site of p-hydroxybenzoate hydroxylase
J. Biol. Chem.
255
9319-9324
1980
Delftia acidovorans
Mueller, F.; Voordouw, G.; van Berkel, W.J.H.; Steennis, P.J.; Visser, S.; van Rooijen, P.J.
A study of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Improved purification, relative molecular mass, and amino acid composition
Eur. J. Biochem.
101
235-244
1979
Pseudomonas fluorescens
van Berkel, W.J.H.; Weijer, W.J.; Mueller, F.; Jekel, P.A.; Beintema, J.J.
Chemical modification of sulfhydryl groups in p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Involvement in catalysis and assignment in the sequence
Eur. J. Biochem.
145
245-256
1984
Pseudomonas fluorescens
Schreuder, H.A.; van der Laan, J.M.; Hol, W.G.J.; Drenth, J.
Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate
J. Mol. Biol.
199
637-648
1988
Pseudomonas fluorescens
Jadan, A.P.; van Berkel, W.J.H.; Golovleva, L.A.; Golovlev, E.L.
Purification and properties of p-hydroxybenzoate hydroxylases from Rhodococcus strains
Biochemistry (Moscow)
66
898-903
2001
Rhodococcus opacus, Rhodococcus rhodnii, Rhodococcus rhodochrous, Rhodococcus sp., Rhodococcus rhodnii 135, Rhodococcus rhodochrous 172, Rhodococcus sp. 400
Moran, G.R.; Entsch, B.; Palfey, B.A.; Ballou, D.P.
Mechanistic insights into p-hydroxybenzoate hydroxylase from studies of the mutant Ser212Ala
Biochemistry
38
6292-6299
1999
Pseudomonas aeruginosa (P20586)
Fernandez, J.; Dimarco, A.A.; Ornston, L.N.; Harayama, S.
Purification and characterization of Acinetobacter calcoaceticus 4-hydroxybenzoate 3-hydroxylase after its overexpression in Escherichia coli
J. Biochem.
117
1261-1266
1995
Acinetobacter calcoaceticus
Suarez, M.; Martin, M.; Ferrer, E.; Garrido-Pertierra, A.
Purification and characterization of 4-hydroxybenzoate 3-hydroxylase from a Klebsiella pneumoniae mutant strain
Arch. Microbiol.
164
70-77
1995
Klebsiella pneumoniae
Sterjiades, R.
Properties of NADH/NADPH-dependent p-hydroxybenzoate hydroxylase from Moraxella sp
Biotechnol. Appl. Biochem.
17
77-90
1993
Moraxella sp., Moraxella sp. GU2
-
Salituro, F.G.; Demeter, D.A.; Weintraub, H.J.R.; Lippert, B.J.; Resvick, R.J.; McDonald, I.A.
Multisubstrate inhibition of 4-hydroxybenzoate 3-monooxygenase
J. Med. Chem.
37
4076-4078
1994
Pseudomonas fluorescens
van Berkel, W.J.H.; Eppink, M.H.M.; Schreuder, H.A.
Crystal structure of p-hydroxybenzoate hydroxylase reconstituted with the modified FAD present in alcohol oxidase from methylotrophic yeasts: evidence for an arabinoflavin
Protein Sci.
3
2245-2253
1994
Pseudomonas fluorescens
Abe, I.; Kashiwagi, K.; Noguchi, H.
Antioxidative galloyl esters as enzyme inhibitors of p-hydroxybenzoate hydroxylase
FEBS Lett.
483
131-134
2000
Pseudomonas aeruginosa, Pseudomonas fluorescens (P00438)
Eppink, M.H.M.; Schreuder, H.A.; Van Berkel, W.J.H.
Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding
Eur. J. Biochem.
253
194-201
1998
Pseudomonas fluorescens
Seibold, B.; Matthes, M.; Eppink, M.H.M.; Lingens, F.; Van Berkel, W.J.H.; Mueller, R.
4-Hydroxybenzoate hydroxylase from Pseudomonas sp. CBS3. Purification, characterization, gene cloning, sequence analysis and assignment of structural features determining the coenzyme specificity
Eur. J. Biochem.
239
469-478
1996
Pseudomonas sp., Pseudomonas sp. CBS3
Eppink, M.H.M.; Schreuder, H.A.; Van Berkel, W.J.H.
Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants
J. Biol. Chem.
273
21031-21039
1998
Pseudomonas fluorescens
Chen, R.; Scott, R.Jr.; Tsugita, A.; Hosokawa, K.
Purification and characterization of p-hydroxybenzoate 3-hydroxylase from Comamonas testosteroni
Res. Commun. Biochem. Cell Mol. Biol.
1
51-60
1997
Acinetobacter sp., Comamonas testosteroni, Pseudomonas sp., Comamonas testosteroni Kh 122-3S
-
Chen, R.; Oki, H.; Scott, R.P.; Yamaguchi, H.; Kusunoki, M.; Matsuura, Y.; Chaen, H.; Tsugita, A.; Hosokawa, K.
Crystallization and further characterization of meta-hydroxybenzoate 4-hydroxylase from Comamonas testosteroni
Res. Commun. Biochem. Cell Mol. Biol.
2
253-274
1998
Comamonas testosteroni
-
Schreuder, H.A.; Mattevi, A.; Obmolova, G.; Kalk, K.H.; Hol, W.G.J.; van der Bolt, F.J.T.; van Berkel, W.J.H.
Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate, 2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry
33
10161-10170
1994
Pseudomonas fluorescens
Lah, M.S.; Palfey, B.A.; Schreuder, H.A.; Ludwig, M.L.
Crystal structures of mutant Pseudomonas aeruginosa p-hydroxybenzoate hydroxylases: The Tyr201Phe, Tyr385Phe, and Asn300Asp variants
Biochemistry
33
1555-1564
1994
Pseudomonas aeruginosa
Suemori, A.; Nakajima, K.; Kurane, R.; Nakamura, Y.
Comparison of chemical inactivation of salicylate 5-hydroxylase, m-hydroxybenzoate 6-hydroxylase, and p-hydroxybenzoate 3-hydroxylase from Rhodococcus erythropolis
Seimei Kogaku Kogyo Gijutsu Kenkyusho Kenkyu Hokoku
2
27-30
1994
Rhodococcus erythropolis
-
Entsch, B.; Palfey, B.A.; Ballou, D.P.; Massey, V.
Catalytic function of tyrosine residues in para-hydroxybenzoate hydroxylase as determined by the study of site-directed mutants
J. Biol. Chem.
266
17341-17349
1991
Pseudomonas aeruginosa
Palfey, B.A.; Entsch, B.; Ballou, D.P.; Massey, V.
Changes in the catalytic properties of p-hydroxybenzoate hydroxylase caused by the mutation Asn300Asp
Biochemistry
33
1545-1554
1994
Pseudomonas aeruginosa
Moran, G.R.; Entsch, B.
Plasmid mutagenesis by PCR for high-level expression of para-hydroxybenzoate hydroxylase
Protein Expr. Purif.
6
164-168
1995
Pseudomonas aeruginosa
Ortiz-Maldonado, M.; Gatti, D.; Ballou, D.P.; Massey, V.
Structure-function correlation of the reaction of reduced nicotinamide analogues with p-hydroxybenzoate hydroxylase substituted with a series of 8-substituted flavins
Biochemistry
38
16636-16647
1999
Pseudomonas aeruginosa
Ortiz-Maldonado, M.; Aeschliman, S.M.; Ballou, D.P.; Masey, V.
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl flavin
Biochemistry
40
8705-8716
2001
Pseudomonas aeruginosa
Palfey, B.A.; Basu, R.; Frederick, K.K.; Entsch, B.; Ballou, D.P.
Role of protein flexibility in the catalytic cycle of p-hydroxybenzoate hydroxylase elucidated by the Pro293Ser mutant
Biochemistry
41
8438-8446
2002
Pseudomonas aeruginosa
Ortiz-Maldonado, M.; Entsch, B.; Ballou, D.P.
Conformational changes combined with charge-transfer interactions are essential for reduction in catalysis by p-hydroxybenzoate hydroxylase
Biochemistry
42
11234-11242
2003
Pseudomonas aeruginosa
Ortiz-Maldonado, M.; Entsch, B.; Ballou, D.P.
Oxygen reactions in p-hydroxybenzoate hydroxylase utilize the H-bond network during catalysis
Biochemistry
43
15246-15257
2004
Pseudomonas aeruginosa
Ortiz-Maldonado, M.; Cole, L.J.; Dumas, S.M.; Entsch, B.; Ballou, D.P.
Increased positive electrostatic potential in p-hydroxybenzoate hydroxylase accelerates hydroxylation but slows turnover
Biochemistry
43
1569-1579
2004
Pseudomonas aeruginosa
Wang, J.; Ortiz-Maldonado, M.; Entsch, B.; Massey, V.; Ballou, D.; Gatti, D.L.
Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase
Proc. Natl. Acad. Sci. USA
99
608-613
2002
Pseudomonas aeruginosa (P20586)
Frederick, K.K.; Palfey, B.A.
Kinetics of proton-linked flavin conformational changes in p-hydroxybenzoate hydroxylase
Biochemistry
44
13304-13314
2005
Pseudomonas aeruginosa (P20586)
Bertani, I.; Kojic, M.; Venturi, V.
Regulation of the p-hydroxybenzoic acid hydroxylase gene (pobA) in plant-growth-promoting Pseudomonas putida WCS358
Microbiology
147
1611-1620
2001
Pseudomonas putida (Q9R9T1), Pseudomonas putida, Pseudomonas putida WCS358 (Q9R9T1), Pseudomonas putida WCS358
Kwon, S.Y.; Kang, B.S.; Kim, G.H.; Kim, K.J.
Expression, purification, crystallization and initial crystallographic characterization of the p-hydroxybenzoate hydroxylase from Corynebacterium glutamicum
Acta Crystallogr. Sect. F
F63
944-946
2007
Corynebacterium glutamicum
Huang, Y.; Zhao, K.X.; Shen, X.H.; Jiang, C.Y.; Liu, S.J.
Genetic and biochemical characterization of a 4-hydroxybenzoate hydroxylase from Corynebacterium glutamicum
Appl. Microbiol. Biotechnol.
78
75-83
2008
Corynebacterium glutamicum
Chang, H.K.; Zylstra, G.J.
Examination and expansion of the substrate range of m-hydroxybenzoate hydroxylase
Biochem. Biophys. Res. Commun.
371
149-153
2008
Comamonas testosteroni (Q6SSJ6), Comamonas testosteroni GZ39 (Q6SSJ6), Comamonas testosteroni GZ39
Kudryashova, E.V.; Visser, A.J.; van Berkel, W.J.
Monomer formation and function of p-hydroxybenzoate hydroxylase in reverse micelles and in dimethylsulfoxide/water mixtures
Chembiochem
9
413-419
2008
Pseudomonas fluorescens
Deveryshetty, J.; Suvekbala, V.; Varadamshetty, G.; Phale, P.S.
Metabolism of 2-, 3- and 4-hydroxybenzoates by soil isolates Alcaligenes sp. strain PPH and Pseudomonas sp. strain PPD
FEMS Microbiol. Lett.
268
59-66
2007
Alcaligenes sp., Pseudomonas sp.
Kim, D.; Kim, S.W.; Choi, K.Y.; Lee, J.S.; Kim, E.
Molecular cloning and functional characterization of the genes encoding benzoate and p-hydroxybenzoate degradation by the halophilic Chromohalobacter sp. strain HS-2
FEMS Microbiol. Lett.
280
235-241
2008
Chromohalobacter sp.
Van Den Berg, P.A.; Grever, K.; Van Hoek, A.; Van Berkel, W.J.; Visser, A.J.
Time-resolved fluorescence analysis of the mobile flavin cofactor in p-hydroxybenzoate hydroxylase
J. Chem. Sci.
119
123-133
2007
Pseudomonas fluorescens
-
Cui, Y.; Barford, J.P.; Renneberg, R.
Development of an L-glutamate biosensor using the coimmobilization of L-glutamate dehydrogenase and p-hydroxybenzoate hydroxylase on a Clark-type electrode
Sens. Actuators B Chem.
B127
358-361
2007
Pseudomonas sp.
-
Zimmermann, T.; Sorg, T.; Siehler, S.Y.; Gerischer, U.
Role of Acinetobacter baylyi Crc in catabolite repression of enzymes for aromatic compound catabolism
J. Bacteriol.
191
2834-2842
2009
Acinetobacter baylyi, Acinetobacter baylyi ADPU54
Chen, Y.; Peng, Y.; Dai, C.; Ju, Q.
Biodegradation of 4-hydroxybenzoic acid by Phomopsis liquidambari
Appl. Soil Ecol.
51
102-110
2011
Diaporthe liquidambaris, Diaporthe liquidambaris B3
Donoso, R.A.; Perez-Pantoja, D.; Gonzalez, B.
Strict and direct transcriptional repression of the pobA gene by benzoate avoids 4-hydroxybenzoate degradation in the pollutant degrader bacterium Cupriavidus necator JMP134
Environ. Microbiol.
13
1590-1600
2011
Cupriavidus necator, Cupriavidus necator JMP 134-1
Romero-Silva, M.J.; Mendez, V.; Agullo, L.; Seeger, M.
Genomic and functional analyses of the gentisate and protocatechuate ring-cleavage pathways and related 3-hydroxybenzoate and 4-hydroxybenzoate peripheral pathways in Burkholderia xenovorans LB400
PLoS ONE
8
e56038
2013
Paraburkholderia xenovorans
Chen, Z.; Shen, X.; Wang, J.; Wang, J.; Yuan, Q.; Yan, Y.
Rational engineering of p-hydroxybenzoate hydroxylase to enable efficient gallic acid synthesis via a novel artificial biosynthetic pathway
Biotechnol. Bioeng.
114
2571-2580
2017
Pseudomonas aeruginosa
Dalvi, S.; Youssef, N.H.; Fathepure, B.Z.
Microbial community structure analysis of a benzoate-degrading halophilic archaeal enrichment
Extremophiles
20
311-321
2016
Haloferax volcanii, Haloferax volcanii DS2
Ceveryshetty, J.; Suvekbala, V.; Varadamshetty, G.; Phale, P.S.
Metabolism of 2-, 3- and 4-hydroxybenzoates by soil isolates Alcaligenes sp. strain PPH and Pseudomonas sp. strain PPD
FEMS Microbiol. Lett.
268
59-66
2007
Alcaligenes sp. PPH, Pseudomonas sp. PPD
Van Den Berg, P.A.; Grever, K.; Van Hoek, A.; Van Berkel, W.J.; Visser, A.J.
Time-resolved fluorescence analysis of the mobile flavin cofactor in p-hydroxybenzoate hydroxylase
J. Chem. Sci.
119
123-133
2007
Pseudomonas fluorescens
-
Wang, J.-Y.; Zhou, L.; Chen, B.; Sun, S.; Zhang, W.; Li, M.; Tang, H.; Jiang, B.-L.; Tang, J.L.; He, Y.-W.
A functional 4-hydroxybenzoate degradation pathway in the phytopathogen Xanthomonas campestris is required for full pathogenicity
Sci. Rep.
5
18456
2015
Xanthomonas campestris, Xanthomonas campestris ATCC 33913
-
Cui, Y.; Barford, J.P.; Renneberg, R.
Development of an L-glutamate biosensor using the coimmobilization of L-glutamate dehydrogenase and p-hydroxybenzoate hydroxylase on a Clark-type electrode
Sens. Actuators B Chem.
B127
358-361
2007
Pseudomonas sp.
-
Maxel, S.; Aspacio, D.; King, E.; Zhang, L.; Acosta, A.P.; Li, H.
A growth-based, high-throughput selection platform enables remodeling of 4-hydroxybenzoate hydroxylase active site
ACS Catal.
10
6969-6974
2020
Pseudomonas aeruginosa (P20586), Pseudomonas aeruginosa, Pseudomonas aeruginosa ATCC 15692 (P20586), Pseudomonas aeruginosa 1C (P20586), Pseudomonas aeruginosa PRS 101 (P20586), Pseudomonas aeruginosa DSM 22644 (P20586), Pseudomonas aeruginosa CIP 104116 (P20586), Pseudomonas aeruginosa LMG 12228 (P20586), Pseudomonas aeruginosa JCM 14847 (P20586)
Lazar, J.T.; Shuvalova, L.; Rosas-Lemus, M.; Kiryukhina, O.; Satchell, K.J.F.; Minasov, G.
Structural comparison of p-hydroxybenzoate hydroxylase (PobA) from Pseudomonas putida with PobA from other Pseudomonas spp. and other monooxygenases
Acta Crystallogr. F Struct. Biol. Commun.
75
507-514
2019
Pseudomonas putida (Q88H28), Pseudomonas putida, Pseudomonas putida DSM 6125 (Q88H28)
Lazar, J.T.; Shuvalova, L.; Rosas-Lemus, M.; Kiryukhina, O.; Satchell, K.J.F.; Minasov, G.
Structural comparison of p-hydroxybenzoate hydroxylase (PobA) from Pseudomonas putida with PobA from other Pseudomonas spp. and other monooxygenases
Acta Crystallogr. Sect. F
75
507-514
2019
Pseudomonas putida (Q88H28), Pseudomonas putida, Pseudomonas putida KT-2440 (Q88H28)
Westphal, A.H.; Tischler, D.; van Berkel, W.J.H.
Natural diversity of FAD-dependent 4-hydroxybenzoate hydroxylases
Arch. Biochem. Biophys.
702
108820
2021
Aspergillus niger, Aspergillus niger N402
Moriwaki, Y.; Yato, M.; Terada, T.; Saito, S.; Nukui, N.; Iwasaki, T.; Nishi, T.; Kawaguchi, Y.; Okamoto, K.; Arakawa, T.; Yamada, C.; Fushinobu, S.; Shimizu, K.
Understanding the molecular mechanism underlying the high catalytic activity of p-hydroxybenzoate hydroxylase mutants for producing gallic acid
Biochemistry
58
4543-4558
2019
Pseudomonas aeruginosa (P20586), Pseudomonas aeruginosa ATCC 15692 (P20586), Pseudomonas aeruginosa 1C (P20586), Pseudomonas aeruginosa PRS 101 (P20586), Pseudomonas aeruginosa DSM 22644 (P20586), Pseudomonas aeruginosa CIP 104116 (P20586), Pseudomonas aeruginosa LMG 12228 (P20586), Pseudomonas aeruginosa JCM 14847 (P20586)
Westphal, A.H.; Tischler, D.; Heinke, F.; Hofmann, S.; Groening, J.A.D.; Labudde, D.; van Berkel, W.J.H.
Pyridine nucleotide coenzyme specificity of p-hydroxybenzoate hydroxylase and related flavoprotein monooxygenases
Front. Microbiol.
9
3050
2018
Cupriavidus pinatubonensis (Q46U22)
Sun, D.; Liu, T.; Dong, Y.; Liu, Q.; Wu, X.; Wang, G.
Coupling p-hydroxybenzoate hydroxylase with the photoresponsive nanozyme for universal dehydrogenase-based bioassays
Sens. Actuators B Chem.
327
128859
2021
Pseudomonas fluorescens (P00438), Pseudomonas fluorescens Migula 1895 (P00438)
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