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Ligand water
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Basic Ligand Information
1alpha-hydroxy-vitamin D3, 1alpha-hydroxyvitamin D3, H2O, H2O ?, H2O[side 2], H3O+, HO-, hydroxyl radical, hydroxyl radicals, OH-, OH radical
BRENDA
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Show all BRENDA pathways known for water
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open all tablesRoles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (10276 results)
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EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-N-acetyl-D-glucosamine + 2 NAD+ + H2O = UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+
-
UDP-N-acetyl-D-glucosamine + NAD+ + H2O = UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + NADH
-
long-chain alcohol + NAD+ + H2O = long-chain carboxylate + NADH
-
IMP + NAD+ + H2O = XMP + NADH + H+
761825, 762347, 760707, 760879, 761713, 761804, 741229, 760262, 760962, 740742, 761033, 762432, 740801, 740809, 760836, 760984, 761406, 761611, 761700, 740794, 739820, 722326, 739794, 736152, 741245, 741400, 760699, 761676, 761987, 739950, 761499, 740217, 740342, 740417, 760704, 760826, 728783
-
inosine 5'-diphosphate + NAD+ + H2O = xanthosine 5'-diphosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
347960, 347938, 347941, 667965, 668351, 347936, 667626, 667644, 667219, 669310, 347932, 347944, 347955, 347933, 667473, 347916, 667935, 667976, 667980, 670881, 667921, 667937, 667938, 667573, 347917, 347910, 667508, 347921
-
UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 2 H+
-
UDP-glucose + 2 NAD+ + H2O = UDP-glucuronic acid + 2 NADH + 2 H+
-
UDPglucose + NAD+ + H2O = UDPglucuronate + NADH
286299, 286302, 286303, 286292, 286293, 286305, 286304, 286295, 286296, 286290, 286291, 286298, 286300, 286306, 286307, 286297, 286294, 286301
-
L-histidinal + NAD+ + H2O = L-histidine + NADH + H+
286325, 286330, 286331, 286333, 286334, 286335, 286336, 286338, 286339, 286322, 286329, 286337, 286332, 286340, 286323, 286324, 286326, 286327, 286328, 656358
-
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
286325, 286330, 286331, 286333, 286334, 286335, 286336, 286338, 286339, 286322, 286329, 286337, 286332, 286340, 286323, 286324, 286326, 286327, 286328, 657194
-
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 3 H+
-
(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O = (R)-sulfolactate + 2 NADH + 2 H+
-
4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+ + H2O = 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH + 2 H+
-
UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+
-
UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+
-
D-glucose 6-phosphate + H2O + NADP+ = D-gluconate 6-phosphate + NADPH + H+
287015, 287017, 287014, 287010, 287011, 287006, 287008, 286992, 286976, 286977, 286983, 286991, 286984, 286979, 286980, 287001, 286978, 286998, 286996, 286985, 286993, 286819, 287012, 287013, 286987, 286999, 286982, 286995, 286997, 287003, 287009, 287016
-
D-glucose 6-phosphate + NADP+ + H2O = D-gluconate 6-phosphate + NADPH + H+
-
betaine aldehyde + O2 + H2O = betaine + H2O2
-
beta-D-glucose + O2 + H2O = D-glucono-1,5-lactone + H2O2
389787, 389788, 389789, 389790, 389792, 389793, 389794, 389796, 389797, 389798, 389799, 389801, 389802, 389803, 389804, 389805, 389806, 389807, 389813, 389815, 389816, 389817, 389819, 389821, 389822, 389823, 389824, 389825, 389827, 713259, 389811, 389814, 389820, 389800, 389785, 389791, 389810, 389808, 389809, 389826, 389818, 710903, 712661, 389786, 389784
-
5-(hydroxymethyl)furfural + 3 O2 + 2 H2O = furan-2,5-dicarboxylate + 3 H2O2
-
benzoyl-CoA + oxidized electron donor + H2O = 4-hydroxybenzoyl-CoA + reduced electron donor
-
benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin
-
protocatechuyl-CoA + oxidized ferredoxin + H2O = 3-hydroxybenzoyl-CoA + reduced ferredoxin
-
2 H2O + 2 plastoquinone + 4 hv = O2 + 2 plastoquinol
-
4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+
-
coelenterazine disulfate + ATP + O2 + H2O = coelenteramide disulfate + AMP + CO2 + diphosphate
-
beta-carotene + 2-oxoglutarate + O2 + H2O = canthaxanthin + succinate + CO2 + 4 H+
-
anthranilic acid + NAD(P)H + O2 + H2O = catechol + CO2 + NAD(P)+ + NH3
-
3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + O2 + H3O+ = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+ + H2O
-
11-deoxycortisol + adrenal ferredoxin + H2O = cortisol + reduced adrenal ferredoxin + O2
-
a [histone H3]-N6,N6-dimethyl-L-lysine4 + O2 + 2 H2O = a [histone H3]-L-lysine4 + 2 formaldehyde + 2 H2O2
-
[histone H3]-N6,N6-dimethyl-L-lysine4 + 2 acceptor + 2 H2O = [histone H3]-L-lysine4 + 2 formaldehyde + 2 reduced acceptor
-
[histone H3]-N6,N6-dimethyl-L-lysine 4 + acceptor + H2O = [histone H3]-N6-methyl-L-lysine 4 + formaldehyde + reduced acceptor
-
[histone H3]-N6,N6-methyl-L-lysine 4 + acceptor + H2O = [histone H3]-L-lysine 4 + formaldehyde + reduced acceptor
-
2 Fe(II) + H2O2 + 2 H2O = 2 [FeO(OH)] + 4 H+
2 Fe(II) + O2 + 4 H2O = 2 [FeO(OH)] + 4 H+ + H2O2
Fe(II) + O2 + H2O = [FeO(OH)] + H+ + H2O2
Mn2+ + O2 + H2O = MnO2+ + H+
-
ATP + a [Co(II) dimethylamine-specific corrinoid protein] + reduced acceptor + H2O = ADP + phosphate + a [Co(I) dimethylamine-specific corrinoid protein] + acceptor
-
ATP + a [Co(II) methylamine-specific corrinoid protein] + reduced acceptor + H2O = ADP + phosphate + a [Co(I) methylamine-specific corrinoid protein] + acceptor
-
ATP + a [Co(II) trimethylamine-specific corrinoid protein] + reduced acceptor + H2O = ADP + phosphate + a [Co(I) trimethylamine-specific corrinoid protein] + acceptor
-
CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O = CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+
-
(2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+
-
2 2-hydroxypurine + 2 NAD+ + 2 H2O = xanthine + 2,8-dihydroxypurine + 2 NADH + 2 H+
-
3 purine + 3 NAD+ + 3 H2O = hypoxanthine + 8-hydroxypurine + 2-hydroxypurine + 3 NADH + 3 H+
-
2-amino-4-hydroxy-pterin + NAD+ + H2O = isoxanthopterin + NADH
-
hypoxanthine + NAD+ + H+ + O2- + H2O = xanthine + NADH + H2O2
-
hypoxanthine + NAD+ + H2O = xanthine + NADH + H+
703310, 703626, 644605, 644590, 644569, 644555, 644564, 644589, 644562, 644603, 644581, 644563, 644586, 644607, 706259, 704636, 644617
-
xanthine + NAD+ + H2O = urate + NADH
644572, 644606, 644613, 644560, 644578, 644584, 644595, 644598, 644610, 644590, 644557, 644558, 644555, 644564, 644609, 644594, 644561, 644562, 644603, 644614, 644581, 644583, 644575, 644563, 644582, 644599, 644601, 644571, 644607, 644588, 644618, 644568, 644616, 644579, 644600, 644593, 644617, 644604, 644589, 644565, 644605, 394699, 644608, 644569, 644559, 644556, 644576, 644574, 644567, 644587, 644580
-
xanthine + NAD+ + H2O = urate + NADH + H+
703310, 703626, 744450, 704842, 702963, 704822, 706057, 706838, 706259, 704425, 745069, 746009, 746030, 746031, 704636, 744875, 746016, 745314, 744255, 715273, 744521
-
xanthine + O2 + H2O = urate + O2- + 2 H+
644582, 644615, 644578, 644584, 644598, 644567, 644587, 644594, 644603, 644580, 644586, 644593, 644592, 644570, 644579, 644589, 644581, 644574, 644562, 644597, 644591, 644600, 644588
-
nicotinate + H2O + electron acceptor = 6-hydroxynicotinate + reduced electron acceptor
-
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+
-
lupanine + pyrroloquinoline quinone + H2O = 17-hydroxylupanine + pyrroloquinoline quinol
-
hypoxanthine + 2 H2O + 2 O2 = urate + 2 H2O2
-
hypoxanthine + NAD+ + H2O = xanthine + NADH + H+
-
xanthine + H2O + O2 = urate + H2O2
684329, 684352, 715069, 675050, 684783, 687984, 690205, 689699, 714464, 714644, 684878, 685300, 686525, 689276, 714785, 715264, 716010, 715723, 688764, 689189, 744517, 745064, 745314, 744875, 687784, 715538, 744493, 744841, 745108, 745461, 745585, 744744, 745473, 745709, 657487, 685804, 686890, 688155, 685028, 688048, 688056, 685516, 686881, 686057, 686064, 687263, 689994, 686866, 674374, 686461, 684354, 690202, 685983, 689164, 687898, 686553, 688146, 715273
-
xanthine + O2 + H2O = urate + H2O2
-
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O = ribonucleoside triphosphate + reduced thioredoxin
-
ribonucleoside triphosphate + reduced thioredoxin + H2O = 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O
437899, 437889, 437898, 437891, 437893, 437897, 437900, 437904, 437892, 437906, 437887, 437890, 437894, 437896, 437901, 437902, 437903, 437888, 437895
-
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol + H2O = 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol
-
2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol
-
2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol
-
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced ferredoxin
-
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin
-
isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor
-
4-methylphenol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor + H+
-
2 S-adenosyl-L-methionine + a bacteriochlorophyllide c + H2O = a bacteriochlorophyllide e + 2 5'-deoxyadenosine + 2 L-methionine
-
S-adenosyl-L-methionine + a 7-(hydroxymethyl)bacteriochlorophyllide c + H2O = a 7-(dihydroxymethyl)bacteriochlorophyllide c + 5'-deoxyadenosine + L-methionine
-
S-adenosyl-L-methionine + a bacteriochlorophyllide c + H2O = a 7-(hydroxymethyl)bacteriochlorophyllide c + 5'-deoxyadenosine + L-methionine
-
cholest-4-en-3-one + acceptor + H2O = 25-hydroxycholest-4-en-3-one + reduced acceptor
-
1-testosterone + H2O + acceptor = 1,17-dihydroxy-androstan-3-one + reduced acceptor
-
ethylbenzene + H2O + acceptor = (S)-1-phenylethanol + reduced acceptor
-
queuosine34 in tRNA + acceptor + H2O = epoxyqueuosine34 in tRNA + reduced acceptor
-
ferroheme o + H2O + 2 acceptor = ferroheme a + 2 reduced acceptor
-
8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + H2 + 2 NH3 + 16 ADP + 16 phosphate
440145, 440143, 440144, 440151, 440142, 440171, 440176, 440177, 440140, 440146, 440147, 440149, 440152, 440157, 440166, 440174, 440153, 440159, 440164, 440180, 440138, 440150, 440154, 440155, 440156, 440158, 440163, 440175, 440178, 440179, 440181, 440182, 440183, 440184, 440187, 440169, 440162, 440148, 440165, 440170, 440161, 440167, 440168, 440160, 440134, 440186, 440188, 742740
-
2 reduced ferredoxin + 2 H+ + acetylene + 2 ATP + 2 H2O = 2 oxidized ferredoxin + ethylene + 2 ADP + 2 phosphate
-
reduced ferredoxin + H+ + N2 + ATP + H2O = oxidized ferredoxin + H2 + NH3 + ADP + phosphate
658901, 744780, 658010, 659426, 746480, 658769, 684881, 745127, 745155, 658040, 658372, 658483, 660287
-
12 reduced ferredoxin + 12 H+ + N2 + 40 ATP + 40 H2O = 12 oxidized ferredoxin + 3 H2 + 2 NH3 + 40 ADP + 40 phosphate
-
6 reduced flavodoxin + N2 + 6 H2O + 6 ATP = 6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate
-
reduced flavodoxin + N2 + ATP + H2O = oxidized flavodoxin + H2 + NH3 + ADP + phosphate
-
reduced flavodoxin II + N2 + ATP + H2O = oxidized flavodoxin II + H2 + NH3 + ADP + phosphate
-
5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NAD+ + H2O = 3-hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + H+
-
succinate semialdehyde + NAD+ + H2O = succinate + NADH + 2 H+
-
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+
-
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+
-
3-aminopropanal + NAD+ + H2O = 3-aminopropanoate + NADH + H+
-
4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+
-
4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + H+
-
4-aminobutyraldehyde + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+
-
(S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+
-
2-dehydro-3-deoxy-D-glucose + NAD+ + H2O = 2-dehydro-3-deoxy-D-gluconate + NADH + H+
-
methylglyoxal + NAD+ + H2O = pyruvate + NADH + H+
-
succinate semialdehyde + NAD+ + H2O = succinate + NADH
-
succinate semialdehyde + NAD+ + H2O = succinate + NADH + 2 H+
-
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
-
2-methyl-3-oxopropanoate + CoA + H2O + NAD+ = propanoyl-CoA + HCO3- + NADH
-
benzaldehyde + NAD+ + H2O = benzoate + NADH + H+
390242, 4801, 4814, 288329, 288330, 288331, 288333, 389583, 390225, 724140, 288328, 389586, 389587, 390233, 390237, 390239, 390240, 390241, 390228, 390234, 390243, 700759, 699798
-
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O = 3,4-dihydroxyphenylacetic acid + NADH + H+
-
3-hydroxypropionaldehyde + NAD+ + H2O = 3-hydroxypropionic acid + NADH + H+
-
alpha-aminoadipate semialdehyde + NAD+ + H2O = alpha-aminoadipate + NADH + H+
-
2-aminomuconate 6-semialdehyde + NAD+ + H2O = 2-aminomuconate + NADH + 2 H+
-
2-aminomuconate-6-semialdehyde + NAD+ + H2O = 2-aminomuconate + NADH
-
2-hydroxymuconic acid semialdehyde + NAD+ + H2O = 2-hydroxymuconate + NADH + H+
-
all-trans-retinal + H2O + NAD+ = all-trans-retinoate + NADH + 2 H+
-
all-trans-retinal + NAD+ + H2O = all-trans-retinoate + NADH
-
all-trans-retinal + NAD+ + H2O = all-trans-retinoate + NADH + 2 H+
-
retinal + NAD+ + H2O = retinoate + NADH
-
retinal + NAD+ + H2O = retinoate + NADH + 2 H+
-
retinal + NAD+ + H2O = retinoate + NADH + H+
673325, 696437, 699951, 711154, 724722, 668500, 725461, 675508, 673242, 673251, 673254, 677080, 672991, 671851
-
4-hydroxyphenylacetaldehyde + NAD+ + H2O = 4-hydroxyphenylacetate + NADH + H+
-
phenylacetaldehyde + NAD+ + H2O = ?
-
phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + 2 H+
-
phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+
-
formaldehyde + NAD+ + H2O = formate + NADH + 2 H+
-
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O = 3,4-dihydroxyphenylacetate + NADH + H+
-
4-(trimethylamino)butyraldehyde + NAD+ + H2O = 4-(trimethylamino)butyrate + NADH + 2 H+
-
4-N-trimethylaminobutyraldehyde + NAD+ + H2O = gamma-butyrobetaine + NADH + H+
-
4-trimethylaminobutyraldehyde + NAD+ + H2O = 4-N-trimethylaminobutyrate + NADH + H+
-
4-trimethylammoniobutanal + NAD+ + H2O = 4-trimethylammoniobutanoate + NADH + 2 H+
-
cis,cis-9,12-octadecadienal + NAD+ + H2O = cis,cis-9,12-octadecadienoic acid + NADH
-
2-keto-3-deoxy-D-glucose + NADP+ + H2O = 2-keto-3-deoxy-D-gluconic acid + NADPH + H+
-
methylglyoxal + NADP+ + H2O = pyruvate + NADPH + H+
-
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH
-
salicylaldehyde + NAD+ + H2O = salicylate + NADH
-
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O = 4-hydroxy-3-methoxybenzoate + NADH + H+
-
vanillin + NAD+ + H2O = vanillate + NADH + 2 H+
-
benzaldehyde + NADP+ + H2O = benzoate + NADPH
-
N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH + 2 H+
-
N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH + H+
-
3,4-dehydroadipyl-CoA semialdehyde + NADP+ + H2O = 3,4-dehydroadipyl-CoA + NADPH + H+
-
cis-3,4-dehydroadipyl-CoA semialdehyde + NADP+ + H2O = cis-3,4-dehydroadipyl-CoA + NADPH + H+
-
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+
-
betaine aldehyde + NAD(P)+ + H2O = glycine betaine + NAD(P)H + H+
-
betaine aldehyde + NAD+ + H2O = betaine + NADH
390363, 390361, 390333, 390331, 390336, 390362, 390339, 390359, 390342, 390334, 390337, 390338, 390329, 390330, 390335, 390340, 390341, 390328
-
betaine aldehyde + NAD+ + H2O = betaine + NADH + 2 H+
739903, 741452, 763411, 740020, 762849, 740512, 763099, 740237, 741404, 740335, 740295, 763552, 763372, 763469, 763558, 763162, 763598, 762897, 686072
-
betaine aldehyde + NAD+ + H2O = betaine + NADH + H+
726467, 741394, 740510, 726249, 741442, 739789, 740506, 741169, 741463, 740513, 688198, 656628, 655111, 689474
-
betaine aldehyde + NAD+ + H2O = glycine betaine + NADH + H+
-
2-hydroxymuconate-6-semialdehyde + NAD+ + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H+
-
1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH
-
D-glyceraldehyde 3-phosphate + H2O + NADP+ = (2R)-3-phosphoglycerate + NADPH + 2 H+
-
D-glyceraldehyde 3-phosphate + NADP+ + H2O = 3-phospho-D-glycerate + NADPH + 2 H+
-
D-glyceraldehyde 3-phosphate + NADP+ + H2O = 3-phospho-D-glycerate + NADPH + H+
-
D-glyceraldehyde 3-phosphate + NAD(P)+ + H2O = 3-phospho-D-glycerate + NAD(P)H + 2 H+
-
D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + 2 H+
-
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP+ + H2O = 3-oxo-5,6-dehydrosuberyl-CoA + NADPH + H+
-
3,6-anhydro-alpha-L-galactopyranose + NAD(P)+ + H2O = 3,6-anhydro-alpha-L-galactonate + NAD(P)H + H+
-
3,6-anhydro-alpha-L-galactopyranose + NAD+ + H2O = 3,6-anhydro-L-galactonate + NADH + H+
-
3,6-anhydro-alpha-L-galactopyranose + NADP+ + H2O = 3,6-anhydro-L-galactonate + NADPH + H+
-
2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxy-2-methylpropanoate + NADH + H+
-
3-hydroxypropionaldehyde + NAD+ + H2O = 3-hydroxypropanoate + NADH + 2 H+
-
gamma-glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O = 4-(glutamylamino) butanoate + NADH + 2 H+
-
3 brimonidine + 4 H2O + 4 O2 = 2-oxobrimonidine + 3-oxobrimonidine + 2,3-dioxobrimonidine + 4 H2O2
-
4-hydroxypyrazolo(3,4-d)pyrimidine + O2 + H2O = 4,6-dihydroxypyrazolo(3,4-d)pyrimidine + H2O2
-
abscisic aldehyde + H2O + O2 = abscisate + H2O2
-
pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2
-
formylmethanofuran + H2O + oxidized ferredoxin = CO2 + methanofuran + reduced ferredoxin
-
formylmethanofuran + H2O + oxidized ferredoxin [iron-sulfur] cluster = CO2 + methanofuran + reduced ferredoxin [iron-sulfur] cluster
-
CO + H2O + acceptor = CO2 + reduced acceptor
CO + H2O + acceptor = CO2 + reduced acceptor
CO + H2O + acceptor = CO2 + reduced acceptor
CO + H2O + electron acceptor = ?
CO + H2O + electron acceptor = ?
CO + H2O + electron acceptor = ?
CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin
CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin
CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin
an aldehyde + H2O + oxidized ferredoxin = an acid + H+ + reduced ferredoxin
-
formaldehyde + H2O + oxidized ferredoxin = formate + H+ + reduced ferredoxin
-
phenylacetaldehyde + H2O + oxidized ferredoxin = phenylacetate + H+ + reduced ferredoxin
-
D-glyceraldehyde 3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin
-
D-glyceraldehyde-3-phosphate + H2O + oxidized ferredoxin = 3-phospho-D-glycerate + H+ + reduced ferredoxin
-
4,4'-diapolycopen-4-al + H2O + acceptor = 4,4'-diapolycopen-4-oate + reduced acceptor
-
4,4'-diapolycopene-4,4'-dial + H2O + acceptor = 4,4'-diapolycopene-4,4'-dioate + reduced acceptor
-
acetyl phosphate + NH3 + thioredoxin disulfide + H2O = glycine + phosphate + thioredoxin
636464, 636465, 636466, 636467, 636469, 636470, 636476, 636477, 636471, 636472, 636473, 636475, 636474, 636462, 636468, 484935
-
magnesium-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine + H2O = 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 3 L-methionine
-
7-hydroxy-8-methylisoflavone + 2 NAD+ + 2 H2O = 7,2',3'-trihydroxy-8-methylisoflavone + 2 NADH + 2 H+
-
7-hydroxyisoflavone + 2 NAD+ + 2 H2O = 7,3',4'-trihydroxyisoflavone + 2 NADH + 2 H+
-
3,8-divinyl chlorophyllide a + reduced ferredoxin [iron-sulfur] cluster + ATP + H2O + H+ = bacteriochlorophyllide g + oxidized ferredoxin [iron-sulfur] cluster + ADP + phosphate
-
3-acetyl-3-devinylchlorophyllide a + 2 reduced ferredoxin [iron-sulfur] cluster + ATP + H2O + 2 H+ = bacteriochlorophyllide a + 2 oxidized ferredoxin [iron-sulfur] cluster + ADP + phosphate
-
chlorophyllide a + AH2 + ATP + H2O = 3-deacetyl-3-vinylbacteriochlorophyllide a + A + ADP + phosphate
-
protochlorophyllide + reduced ferredoxin [iron-sulfur] cluster + ATP + H2O + H+ = chlorophyllide a + oxidized ferredoxin [iron-sulfur] cluster + ADP + phosphate
-
chlorophyllide a + reduced ferredoxin + 2 ATP + 2 H2O = protochlorophyllide + oxidized ferredoxin + 2 ADP + 2 phosphate + 2 H+
-
protochlorophyllide a + reduced ferredoxin + 2 ATP + 2 H2O = chlorophyllide a + oxidized ferredoxin + 2 ADP + 2 phosphate
-
2-bromobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 2-bromocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
2-chlorobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 2-chlorocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
2-fluorobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
2-hydroxybenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 2-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
2-methylbenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 2-methylcyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
3-bromobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 3-bromocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
3-chlorobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 3-chlorocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
3-fluorobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 3-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
3-hydroxybenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
3-methylbenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 3-methylcyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
4-bromobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 4-bromocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
4-chlorobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 4-chlorocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
4-ethylbenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 4-ethylcyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
4-fluorobenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 4-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
4-methylbenzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = 4-methylcyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
benzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O = cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate
-
benzoyl-CoA + reduced acceptor + ATP + H2O = cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + ADP + phosphate
-
benzoyl-CoA + reduced ferredoxin + ATP + H2O = cyclohexa-1,5-diene-1-carboxyl-CoA + oxidized ferredoxin + ADP + phosphate
-
2-furoyl-CoA + H2O + acceptor = S-(5-hydroxy-2-furoyl)-CoA + reduced acceptor
-
L-Ala + H2O + NAD+ = pyruvate + NH3 + NADH
349536, 655519, 349598, 349588, 349566, 349591, 349546, 349551, 349567, 6015, 349542, 349545, 349540, 695918
-
L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+
725267, 724147, 759007, 763655, 762828, 763354, 723883, 762981, 763669, 763656, 763206, 763371, 762684, 763144
-
L-erythro-3,5-diaminohexanoate + H2O + NAD+ = 5-amino-3-oxohexanoate + NH3 + NADH + H+
-
(2R,4S)-2,4-diaminopentanoate + H2O + NAD+ = (2R)-2-amino-4-oxopentanoate + NH3 + NADH + H+
-
(2R,4S)-2,4-diaminopentanoate + H2O + NADP+ = (2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+
-
2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H
-
meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+
-
L-lysine + NAD+ + H2O = alpha-aminoadipate delta-semialdehyde + NH3 + NADH
-
L-tryptophan + NAD+ + H2O = (indol-3-yl)pyruvate + NH3 + NADH + H+
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
760442, 724249, 725887, 726164, 726245, 726119, 727059, 726044, 725797, 724888, 724970, 391559, 724596, 724935, 711526, 711875, 710758, 725834, 724938, 763438, 763046, 763775, 763741, 391544, 391558, 661800, 711601, 763098
-
L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH + H+
-
L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+
-
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ = 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ = 3-dehydroquinate + NH3 + NADH + H+
-
(2R,4S)-2,4-diaminopentanoate + H2O + NAD+ = (2R)-2-amino-4-oxopentanoate + NH3 + NADH + H+
-
(2R,4S)-2,4-diaminopentanoate + H2O + NADP+ = (2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+
-
L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+
-
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
-
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
-
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
725506, 726247, 712309, 712263, 724981, 762699, 724938, 725918, 763355, 763438, 762745, 763775, 763046, 763741, 762874, 711601
-
L-glutamate + NADP+ + H2O = 2-oxoglutarate + NADPH + NH3
391688, 391689, 391643, 391659, 391662, 391667, 391675, 391685, 391686, 391641, 391684, 391679, 391652, 391656, 391660, 391647, 391454, 391676, 391663, 391664, 391669, 391657, 391683, 391655, 391651, 37509, 391653, 391665, 391666, 391671, 391650, 391673, 391640, 391648, 391661, 391590, 391677, 391668, 286198, 391639, 391680, 391646, 391682, 391638, 391642, 391644, 391649, 391654, 391672, 391674, 391678, 391687
-
L-valine + NAD(P)+ + H2O = 2-oxoisovalerate + NH3 + NAD(P)H
-
L-erythro-3,5-diaminohexanoate + H2O + NAD+ = 5-amino-3-oxohexanoate + NH3 + NADH + H+
-
L-erythro-3,5-diaminohexanoate + H2O + NADP+ = (S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
L-erythro-3,5-diaminohexanoate + H2O + NADP+ = 5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2
391716, 711325, 711719, 711722, 743140, 391706, 391712, 391726, 391728, 712818, 723870, 391705, 391707, 391708, 391711, 391717, 391718, 391719, 391720, 391721, 391722, 391723, 391724, 391725, 391727, 725959, 391710, 656415, 391713, 724597, 657350, 391714, 711721, 391715, 742426, 743133, 743350, 743836, 743063, 391709, 677271
-
putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2
-
L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2
-
cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + H2O2
-
peptidyl-L-lysyl-peptide + O2 + H2O = peptidyl-allysyl-peptide + NH3 + H2O2
658189, 659197, 724520, 725411, 741494, 742237, 742424, 742874, 657974, 725545, 655021, 659558, 659751, 657782, 658190, 660423
-
[collagen]-L-lysine + O2 + H2O = [collagen]-(S)-2-amino-6-oxohexanoate + NH3 + H2O2
-
L-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + H2O2
391752, 391745, 487988, 742804, 764336, 742803, 391750, 742220, 741611, 741812, 741873, 711868, 725912, 765287, 391748, 391751, 391746, 391747, 391749, 725911
-
L-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2
-
glycine + H2O + O2 = glyoxylate + NH3 + H2O2
-
L-amino acid + H2O + O2 = 2-oxo acid + NH3 + H2O2
-
L-Arg + H2O + O2 = 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
L-His + H2O + O2 = 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
L-Leu + H2O + O2 = 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
L-Lys + H2O + O2 = 6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
L-lysine + H2O + O2 = 6-amino-2-oxohexanoic acid + NH3 + H2O2
-
L-Met + H2O + O2 = 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
L-methionine + H2O + O2 = 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
L-Phe + H2O + O2 = phenylpyruvate + NH3 + H2O2
-
L-Tyr + H2O + O2 = 4-hydroxyphenylpyruvate + NH3 + H2O2
-
L-lysine + O2 + H2O = (S)-2-amino-6-oxohexanoate + H2O2 + NH3
-
L-lysine + O2 + H2O = 2-aminoadipate 6-semialdehyde + H2O2 + NH3
-
histamine + H2O + O2 = (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + O2 + H2O = 5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + NH3 + H2O2
-
5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O = 5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidine-2,3-dione + NH3
-
cephalosporin C + H2O + O2 = 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2
-
D-alanine + H2O + O2 = pyruvate + NH3 + H2O2
699830, 699838, 711720, 696139, 699758, 701073, 699761, 696158, 688440, 712454, 696171, 656415, 654362
-
D-alanine + H2O + O2 = pyruvic acid + NH3 + H2O2
391859, 391828, 391830, 391849, 391860, 391865, 391840, 391853, 391834, 391833, 391844, 391852, 391861, 391841, 391864, 391847, 391848
-
D-amino acid + H2O + O2 = 2-oxocarboxylate + NH3 + H2O2
-
D-histidine + H2O + O2 = 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + H2O2
-
D-isoleucine + H2O + O2 = 3-methyl-2-oxopentanoic acid + NH3 + H2O2
-
D-leucine + H2O + O2 = 4-methyl-2-oxopentanoic acid + NH3 + H2O2
-
D-methionine + H2O + O2 = 4-methylthio-2-oxobutanoic acid + NH3 + H2O2
391828, 391830, 391849, 391860, 391865, 391840, 391853, 391833, 391844, 391852, 391861, 391841, 391864, 391839, 391847, 391848
-
D-norvaline + H2O + O2 = 2-oxopentanoate + NH3 + H2O2
-
D-phenylalanine + H2O + O2 = phenylpyruvic acid + NH3 + H2O2
-
D-proline + H2O + O2 = 2-oxopentanoic acid + NH3 + H2O2
-
D-Ser + H2O + O2 = 2-oxo-3-hydroxypropionate + NH3 + H2O2
-
D-serine + H2O + O2 = 2-oxo-3-hydroxypropionate + NH3 + H2O2
-
D-serine + H2O + O2 = 2-oxo-3-hydroxypropionic acid + NH3 + H2O2
-
D-tryptophan + H2O + O2 = indol-3-pyruvic acid + NH3 + H2O2
-
D-tyrosine + H2O + O2 = 4-hydroxyphenylpyruvic acid + NH3 + H2O2
-
D-valine + H2O + O2 = alpha-ketoisovaleric acid + NH3 + H2O2
-
2 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + 2 H2O + 3 O2 = 1-methyl-4-phenyl-2,3-dihydropyridinium + 1-methyl-4-phenylpyridinium + 4 H2O2
-
5-hydroxytryptamine + H2O + O2 = (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
benzylamine + H2O + O2 = benzaldehyde + NH3 + H2O2
-
kynuramine + H2O + O2 = 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2
-
RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2
-
serotonin + H2O + O2 = (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
pyridoxamine 5'-phosphate + FMN + H2O + 2 H+ = pyridoxal 5'-phosphate + FMNH2 + NH3
-
pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + H2O2
-
pyridoxine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + H2O2
-
2-phenylethylamine + 2 H2O + 2 acceptor = 2-phenylacetic acid + NH3 + 2 reduced acceptor
-
methylamine + H2O + 2 amicyanin = formaldehyde + NH3 + 2 reduced amicyanin
-
beta-phenylethylamine + H2O + 2,6-dichlorophenol indophenol = phenylacetaldehyde + NH3 + reduced 2,6-dichlorophenol indophenol
-
taurine + H2O + bovine heart cytochrome c = 2-sulfoacetaldehyde + NH3 + reduced bovine heart cytochrome c
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADPH + H+
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADPH + H+
-
N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH + H+
-
N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH + H+
-
10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+
724712, 392340, 392350, 392343, 392349, 392351, 392345, 392348, 392352, 392339, 392344, 392354, 392355, 392337
-
10-formyltetrahydropteroylhexaglutamate + NADP+ + H2O = tetrahydropteroylhexaglutamate + CO2 + NADPH
-
10-formyltetrahydropteroylpentaglutamate + NADP+ + H2O = tetrahydropteroylpentaglutamate + CO2 + NADPH
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-lysine + 2-oxoglutarate + NADPH + H+
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-Glu + 2-aminoadipate 6-semialdehyde + NADH
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+
-
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH + H+
-
saccharopine + NAD+ + H2O = L-glutamate + alpha-aminoadipate semialdehyde + NADH + H+
-