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EC 1.14.13.59 Details
show Brenda entryEC number
1.14.13.59
Accepted name
L-lysine N6-monooxygenase (NADPH)
Reaction
L-lysine + NADPH + H+ + O2 = N6-hydroxy-L-lysine + NADP+ + H2O
Other name(s)
lysine N6-hydroxylase,
L-lysine 6-monooxygenase (NADPH) (ambiguous)
Systematic name
L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)
CAS registry number
64295-82-5
Comment
A flavoprotein (FAD). The enzyme from strain EN 222 of Escherichia coli is highly specific for L-lysine; L-ornithine and L-homolysine are, for example, not substrates.
History
created 1999, modified 2001, modified 2012
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.6.99.4 created 1965, deleted 1972 1.6.99.8 created 1972, deleted 2002 1.6.99.9 created 1972, deleted 2002 1.6.99.10 created 1978, deleted 1981 1.6.99.11 created 1989, deleted 2002 1.6.99.12 created 1989, deleted 2002 1.6.99.13 created 1992, deleted 2002 1.14.13.45 created 1992, deleted 2003
