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D-glucose 6-phosphate + H2O
D-glucose + phosphate
additional information
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the enzyme catalytic subunit expression is regulated independently from the glucose-6-phosphate transporter expression by metabolites, overview
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the enzyme is the key enzyme of the gluconeogenesis pathway, and is positively regulated by a extracellular multipolypeptide complex called counting factor, CF, or the CF component coutin, respectively, while the glucokinase activity is inhibited by CF, regulation overview
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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enzyme system is required in hepatic D-glucose phosphorylation
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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key enzyme in D-glucose homeostasis
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the enzyme plays a important role of providing D-glucose during starvation
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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key enzyme in glucose metabolism
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the enzyme is required for the final steps of glycogenolysis and gluconeogenesis
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the brain functional glucose-6-phosphatase complex is capable of endogenous glucose production from glucose 6-phosphate, independent of blood glucose
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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enzyme is one of the rate-limiting enzymes of hepatic glucogenesis
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the enzyme catalyses the terminal reaction of gluconegenesis and glycogenolysis and plays a major role in the contol of blood glucose levels
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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the enzyme is required for the final steps of glycogenolysis and gluconeogenesis
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
dietary regulation of the enzyme in the liver glucose metabolism, overview
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D-glucose 6-phosphate + H2O
D-glucose + phosphate
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enzyme catalyses the final step in both glycogenolysis and glyconeogenesis
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additional information
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the role of the enzyme in muscle is either to produce glucose from glucose 6-phosphate derived from glycogen or to provide the enzymatic basis for a substrate cycle betwen glucose and glucose 6-phosphate in muscle to improve the sensitivity of the mechanism that regulates the rate of glucose phosphorylation
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cells of Dictyostelium discoideum form groups of about 20000 cells. The group size is regulated in part by a negative feedback pathway mediated by a secreted multipolypeptide complex called counting factor. It appears that part of the counting factor signal transduction pathway involves inhibiting the activity of glucose-6-phosphatase, decreasing intracellular glucose levels and affecting the levels of other metabolites, to regulate group size
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the enzyme is involved in the mobilization of glucose from liver cells
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enzyme deficiency causes glycogen storage disease type Ia, GSD-Ia, overview
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enzyme deficiency causes glycogen storage disease type Ia, GSD-Ia, overview
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glucose-6-phosphatase mutations affect protein stability and cause glycogen storgae disease type Ia, GSD-Ia, determined in Argentina, overview
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glucose-6-phosphatase mutations affect protein stability and cause glycogen storgae disease type Ia, GSD-Ia, determined in Argentina, overview
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reduced enzyme activity in woodchuck model of hepatitis virus-induced hepatocellular carcinoma, overview
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the role of the enzyme in muscle is either to produce glucose from glucose 6-phosphate derived from glycogen or to provide the enzymatic basis for a substrate cycle betwen glucose and glucose 6-phosphate in muscle to improve the sensitivity of the mechanism that regulates the rate of glucose phosphorylation
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additional information
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the role of the enzyme in muscle is either to produce glucose from glucose 6-phosphate derived from glycogen or to provide the enzymatic basis for a substrate cycle betwen glucose and glucose 6-phosphate in muscle to improve the sensitivity of the mechanism that regulates the rate of glucose phosphorylation
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additional information
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the role of the enzyme in muscle is either to produce glucose from glucose 6-phosphate derived from glycogen or to provide the enzymatic basis for a substrate cycle betwen glucose and glucose 6-phosphate in muscle to improve the sensitivity of the mechanism that regulates the rate of glucose phosphorylation
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the biosynthetic activity of the enzyme may act in concert with glycogen synthase during amino-acid-induced glycogenesis from glucose. Amino acids may play a role in increasing biosynthetic activity of the enzyme
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the enzyme probably plays a key role in the down-regulation of the calcium signal required for glycogen mobilization
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additional information
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the role of the enzyme in muscle is either to produce glucose from glucose 6-phosphate derived from glycogen or to provide the enzymatic basis for a substrate cycle betwen glucose and glucose 6-phosphate in muscle to improve the sensitivity of the mechanism that regulates the rate of glucose phosphorylation
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the enzyme is involved in sleep
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the main regulatory function of the enzyme is to buffer the glucose 6-phosphate concentration. Hyperglycemia stimulates glucose-6-phosphatase gene transcription
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the activity of glucose-6-phosphate synthesis can serve as an adjunct to glucokinase in hepatic glucose phosphorylation and may function in liver-mediated, adjustable maintanance of blood glucose homeostasis
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final step in gluconeogenesis
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terminal reaction of the pathway of glycogenolysis and gluconeogenesis. Activity of the enzyme is influenced by changes of the phospholipids on the microsomal membrane
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the multicomponent hepatic glucose 6-phosphatase system catalyzes the terminal step of the hepatic glucose production and plays a role in the regulation of blood glucose
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endoplasmic stress may play a role in diabetes, and it results in increased enzyme activity in the liver, overview
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