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3.1.3.9: glucose-6-phosphatase

This is an abbreviated version!
For detailed information about glucose-6-phosphatase, go to the full flat file.

Word Map on EC 3.1.3.9

Reaction

D-glucose 6-phosphate
+
H2O
=
D-glucose
+
phosphate

Synonyms

D-glucose-6-phosphate phosphorylase, G-6-Pase, G6Pase, G6Pase-alpha, G6Pase-beta, G6PC, G6PC-2, G6PC-3, G6Pc1, G6PC2, Glc-6-P phosphohydrolase, Glc-6-Pase-alpha, Glc-6-Pase-beta, glucose 6-phosphatase, glucose 6-phosphate phosphatase, glucose 6-phosphate phosphohydrolase, glucose-6-phosphatase, glucose-6-phosphatase catalytic subunit 2, glucose-6-phosphatase catalytic subunit-related protein, glucose-6-phosphatase catalytic unit 2, glucose-6-phosphatase-alpha, glucose-6-phosphatase-beta, IGRP, islet-specific glucose-6-phosphatase catalytic subunit-related protein, islet-specific glucose-6-phosphatase-related protein, phosphatase, glucose 6-

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.9 glucose-6-phosphatase

Expression

Expression on EC 3.1.3.9 - glucose-6-phosphatase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
2 h after metformin treatment
-
endogenous enzyme gene expression in FAO cells is increased by glycerol administration as well as by the fatty acid oleate. The DNA response element for hepatocyte nuclear factor 4alpha is essential for the transactivation
expression of hepatic glucose-6-phosphatase-alpha is down-regulated in patients With hepatic steatosis
-
the expression of the enzyme is significantly elevated, up to 11fold in Hep-G2 cells under starvation-induced autophagy condition compared to normal condition
-