Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | lumen, the enzyme-alpha and the enzyme-beta are anchored by nine transmembrane helices | Homo sapiens | 5783 | - |
membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate + H2O | Homo sapiens | - |
D-glucose + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
the phosphate-enzyme-beta intermediate | Homo sapiens |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
D-glucose 6-phosphate + H2O = D-glucose + phosphate | The enzyme family comprises two active isozyme: the D-glucose 6-phosphatase-alpha, in which is His176 the amino acid in enzyme that acts as the nucleophile forming the phosphohistidine-enzyme intermediate during catalysis and the D-glucose 6-phosphatase-alpha, in which is His167 the amino acid in enzyme that acts as the nucleophile forming the phosphohistidine-enzyme intermediate during catalysis. Both enzyme-alpha and enzyme-beta couple with the D-glucose 6-phosphate transporter to form an active enzyme complex | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate + H2O | - |
Homo sapiens | D-glucose + phosphate | - |
? |