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Reference on EC 3.1.3.9 - glucose-6-phosphatase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nordlie, R.C.; Sukalski, K.A.
Multifunctional glucose 6-phosphatase: a critical review
The Enzymes of Biological Membranes, 2nd Ed. (Martonosi, A. V. , ed. ), Plenum, New York
2
349-398
1985
Bos taurus, Cyprinus carpio, Cavia porcellus, Gallus gallus, Cricetulus griseus, Oryctolagus cuniculus, Dictyostelium discoideum, Felis catus, Frog, Homo sapiens, Vicugna pacos, Lampetra ayresii, Platyrrhini, Mus musculus, Oncorhynchus mykiss, Rattus norvegicus, salamander
-
Manually annotated by BRENDA team
Countaway, J.L.; Waddel, I.D.; Burchell, A.; Arion, W.J.
The phosphohydrolase component of the hepatic microsomal glucose-6-phosphatase system is a 36.5-kilodalton polypeptide
J. Biol. Chem.
263
2673-2678
1988
Rattus norvegicus
Manually annotated by BRENDA team
Suzuki, S.; Toyota, T.; Suzuki, H.; Goto, Y.
Partial purification from human mononuclear cells and placental plasma membranes of an insulin mediator which stimulates pyruvate dehydrogenase and suppresses glucose-6-phosphatase
Arch. Biochem. Biophys.
235
418-426
1984
Homo sapiens
Manually annotated by BRENDA team
Sawaki, K.; Taguchi, R.; Ikezawa, H.
Studies on the interactions between phospholipids and membrane-bound enzymes in microsomes. Effects of phospholipases C on kinetic properties of the glucose-6-phosphatase system in rat liver microsomes
J. Biochem.
93
537-546
1983
Rattus norvegicus
Manually annotated by BRENDA team
Karnovsky, M.L.; Anchors, J.M.; Zoccoli, M.A.
Glucose-6-phosphatase from cerebrum
Methods Enzymol.
90
396-402
1982
Rattus norvegicus
Manually annotated by BRENDA team
Rymsa, B.; de Groot, H.
Partial purification of rat liver microsomal glucose-6-phosphatase on hydroxylapatite
Biol. Chem. Hoppe-Seyler
369
115-121
1988
Rattus norvegicus
Manually annotated by BRENDA team
Nordlie, R.C.
Kinetic examination of enzyme mechanisms involving branched reaction pathways--a detailed consideration of multifunctional glucose-6-phosphatase
Methods Enzymol.
87
319-353
1982
Mammalia
Manually annotated by BRENDA team
Burchell, A.; Burchell, B.
Identification and purification of a liver microsomal glucose 6-phosphatase
Biochem. J.
205
567-573
1982
Oryctolagus cuniculus
Manually annotated by BRENDA team
Jorgensen, B.M.; Agerbo, P.; Jensen, B.; Borresen, T.; Holmer, G.
Inhibition of microsomal glucose 6-phosphatase by unsaturated aliphatic aldehydes and ketones
Chem. Biol. Interact.
81
209-218
1992
Rattus norvegicus
Manually annotated by BRENDA team
Reczek, P.R.; Villee, C.A.
A purification of microsomal glucose-6-phosphatase from human tissue
Biochem. Biophys. Res. Commun.
107
1158-1165
1982
Homo sapiens
Manually annotated by BRENDA team
Surholt, B.; Newsholme, E.A.
Maximum activities and properties of glucose 6-phosphatase in muscles from vertebrates and invertebrates
Biochem. J.
198
621-629
1981
Acherontia atropos, Agrotis exclamationis, Alitta virens, Apis mellifera, Arctia caja, Bombus hortorum, Bombus pascuorum, Bombus terrestris, Bombus vestalis, Bombyx mori, Calliphora vicina, Cavia porcellus, Columba livia, Crangon crangon, Deilephila elpenor, Gallus gallus, Laothoe populi, Locusta migratoria, Manduca sexta, Mus musculus, Musca domestica, Noctua pronuba, Nymphalis urticae, Oryctolagus cuniculus, Pachnoda ephippiata, Passer domesticus, Phalera bucephala, Phryganea sp., Pieris brassicae, Protophormia terraenovae, Rana temporaria, Rattus norvegicus, Sarcophaga barbata, Schistocerca gregaria, Spilarctia lutea, Vespa vulgaris, Xenopus laevis
Manually annotated by BRENDA team
Bickerstaff, G.F.; Burchell, B.
Studies on the purification of glucose 6-phosphatase from rabbit liver microsomal fraction
Biochem. Soc. Trans.
8
389-390
1980
Oryctolagus cuniculus
Manually annotated by BRENDA team
Nordlie, R.C.; Jorgenson, R.A.
Glucose-6-phosphatase
The Enzymes of Biological Membranes (Martonosi, A. V. , ed. ) Plenum, New York
2
465-491
1976
Anas platyrhynchos, Bos taurus, Canis lupus familiaris, Gallus gallus, Columba livia, Cottus gobio, Oryctolagus cuniculus, Cervidae, Felis catus, Chondrichthyes, Ovis aries, Homo sapiens, Trochilidae, Mus musculus, Necturus maculosus, Lithobates catesbeianus, Rana sp., Rattus norvegicus, Thamnophis sirtalis, Turtle
-
Manually annotated by BRENDA team
Stetten, M.R.; Goldsmith, P.K.
A Limulus glucose-6-phosphatase with phosphotransferase activity characteristic of vertebrate liver microsomes. Its possible evolutionary significance
Biochim. Biophys. Acta
444
835-852
1976
Limulus sp.
Manually annotated by BRENDA team
Anchors, J.M.; Karnovsky, M.L.
Purification of cerebral glucose-6-phosphatase. An enzyme involved in sleep
J. Biol. Chem.
250
6408-6416
1975
Rattus norvegicus
Manually annotated by BRENDA team
Pederson, B.A.; Nordlie, M.A.; Foster, J.D.; Nordlie, R.C.
Effects of ionic strength and chloride ion on activities of the glucose-6-phosphatase system: regulation of the biosynthetic activity of glucose-6-phosphatase by chloride ion inhibition/deinhibition
Arch. Biochem. Biophys.
353
141-151
1998
Rattus norvegicus
Manually annotated by BRENDA team
Metzger, S.; Begleibter, N.; Barash, V.; Drize, O.; Peretz, T.; Shiloni, E.; Chajek-Shaul, T.
Tumor necrosis factor inhibits the transcriptional rate of glucose-6-phosphatase in vivo and in vitro
Metabolism
46
579-583
1997
Mus musculus
Manually annotated by BRENDA team
Nordlie, R.C.
Multifunctional hepatic glucose-6-phosphatase and the tuning' of blood glucose levels
Trends Biochem. Sci.
1
199-202
1976
Rattus norvegicus
-
Manually annotated by BRENDA team
Nordlie, R.C.
Metabolic regulation by multifunctional glucose-6-phosphatase
Curr. Top. Cell. Regul.
8
33-117
1974
Anas platyrhynchos, Canis lupus familiaris, Cavia porcellus, Gallus gallus, Columba livia, Oryctolagus cuniculus, Cervidae, Felis catus, Chondrichthyes, Ovis aries, Homo sapiens, Trochilidae, Mus musculus, Necturus maculosus, Lithobates catesbeianus, Rana sp., Rattus norvegicus, Thamnophis sirtalis, Turtle
Manually annotated by BRENDA team
Colilla, W.; Jorgenson, R.A.; Nordlie, R.C.
Mammalian carbamyl phosphate: glucose phosphotransferase and glucose-6-phosphate phosphohydrolase: extended tissue distribution
Biochim. Biophys. Acta
377
117-125
1975
Bos taurus, Rattus norvegicus
Manually annotated by BRENDA team
Gold, E.W.; Veitch, F.P.
Studies on a pyrophosphatase and glucose-6-phosphatase from Aspergillus oryzae
Biochim. Biophys. Acta
327
166-175
1973
Aspergillus oryzae
Manually annotated by BRENDA team
Cori, C.F.; Garland, R.C.; Wang Chang, H.F.
Purification of particulate glucose-6-phosphatase
Biochemistry
12
3126-3130
1973
Rattus norvegicus
Manually annotated by BRENDA team
Nordlie, R.C.
Glucose-6-phosphatase, hydrolytic and synthetic activities
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
4
543-610
1971
Anas platyrhynchos, Bos taurus, Canis lupus familiaris, Cavia porcellus, Gallus gallus, Columba livia, Astacoidea, Oryctolagus cuniculus, Equus caballus, Felis catus, Frog, Ovis aries, Homo sapiens, Lampetra sp., Marmota sp., Mesocricetus auratus, Platyrrhini, Mus musculus, Necturus maculosus, Rattus norvegicus, Sus scrofa
-
Manually annotated by BRENDA team
Benedetti, A.; Fulceri, M.; Ferro, M.; Comporti, M.
On a possible role for glucose-6-phosphatase in the regulation of liver cell cytosolic concentration
Trends Biochem. Sci.
11
284-285
1986
Rattus norvegicus
-
Manually annotated by BRENDA team
Mithieux, G.; Daniele, N.; Payrastre, B.; Zitoun, C.
Liver microsomal glucose-6-phosphatase is competitively inhibited by the lipid products of phosphatidylinositol 3-kinase
J. Biol. Chem.
273
17-19
1998
Rattus norvegicus
Manually annotated by BRENDA team
Speth, M.; Schulze, H.U.
The purification of a detergent-soluble glucose-6-phosphatase from rat liver
Eur. J. Biochem.
208
643-650
1992
Rattus norvegicus
Manually annotated by BRENDA team
Methieux, G.; Zitoun, C.
Mechanisms by which fatty-acyl-CoA esters inhibit or activate glucose-6-phosphasaes in intact and detergent-treated rat liver microsomes
Eur. J. Biochem.
235
799-803
1996
Rattus norvegicus
Manually annotated by BRENDA team
Claeyssens, S.; Chedeville, A.; Lavoinne, A.
Inhibition of protein phosphatases activates glucose-6-phosphatase in isolated rat hepatocytes
FEBS Lett.
315
7-10
1993
Rattus norvegicus
Manually annotated by BRENDA team
Bode, A.M.; Foster, J.D.; Nordlie, R.C.
Glyconeogenesis from L-proline involves metabolite inhibition of the glucose-6-phosphatase system
J. Biol. Chem.
267
2860-2863
1992
Rattus norvegicus
Manually annotated by BRENDA team
Fulceri, R.; Gamerucci, A.; Scott, H.M.; Giunti, R.; Burchell, A.; Benedetti, A.
Fatty acyl-CoA esters inhibit glucose-6-phosphatase in rat liver microsomes
Biochem. J.
307
391-397
1995
Rattus norvegicus
-
Manually annotated by BRENDA team
Aiston, S.; Trinh, K.Y.; Lange, A.J.; Newgard, C.B.; Agius, L.
Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation
J. Biol. Chem.
274
24559-24566
1999
Rattus norvegicus
Manually annotated by BRENDA team
Arion, W.J.; Canfield, W.K.; Callaway, E.S.; Burger, H.J.; Hemmerle, H.; Schubert, G.; Herling, A.W.; Oekonomopulos, R.
Direct evidence for the involvement of two glucose 6-phosphate-binding sites in the glucose-6-phosphatase activity of intact liver microsomes
J. Biol. Chem.
273
6223-6227
1998
Rattus norvegicus
Manually annotated by BRENDA team
Mithieux, G.; Vega, F.V.; Riou, J.P.
The liver glucose-6-phosphatase of intact microsomes is inhibited and displays sigmoid kinetics in the presence of alpha-ketoglutarate-magnesium and oxaloacetate-magnesium chelates
J. Biol. Chem.
265
20364-20368
1990
Rattus norvegicus
Manually annotated by BRENDA team
Speth, M.; Schulze, H.U.
Protease inhibitors but not proteases inhibit the glucose-6-phosphatase of native rat liver microsomes
Biochem. Biophys. Res. Commun.
183
590-597
1992
Rattus norvegicus
Manually annotated by BRENDA team
Simon, C.; Herling, A.W.; Preibisch, G.; Burger, H.J.
Upregulation of hepatic glucose 6-phosphatase gene expression in rats treated with an inhibitor of glucose-6-phosphatase translocase
Arch. Biochem. Biophys.
373
418-428
2000
Rattus norvegicus
Manually annotated by BRENDA team
Grant, A.; MacGregor, A.M.; Burchell, A.
Characterization of glucose-6-phosphatase in hepatocytes. Effects of amiloride and pentamidine
Biochem. Pharmacol.
42
S27-S32
1991
Rattus norvegicus
Manually annotated by BRENDA team
Clottes, E.; Middleditch, C.; Burchell, A.
Rat liver glucose-6-phosphatase system: light scattering and chemical characterization
Arch. Biochem. Biophys.
408
33-41
2002
Rattus norvegicus
Manually annotated by BRENDA team
von Groote-Bidlingmaier, F.; Schmoll, D.; Orth, H.M.; Joost, H.G.; Becker, W.; Barthel, A.
DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression
Biochem. Biophys. Res. Commun.
300
764-769
2003
Rattus norvegicus
Manually annotated by BRENDA team
Goh, B.H.; Efendic, S.; Khan, A.; Portwood, N.
Evidence for the expression of both the hydrolase and translocase components of hepatic glucose-6-phosphatase in murine pancreatic islets
Biochem. Biophys. Res. Commun.
307
935-941
2003
Mus musculus
Manually annotated by BRENDA team
Van Schaftingen, E.; Gerin, I.
The glucose-6-phosphatase system
Biochem. J.
362
513-532
2002
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Benedetti, A.; Fulceri, R.; Allan, B.B.; Houston, P.; Sukhodub, A.L.; Marcolongo, P.; Ethell, B.; Burchell, B.; Burchell, A.
Histone 2A stimulates glucose-6-phosphatase activity by permeabilization of liver microsomes
Biochem. J.
367
505-510
2002
Rattus norvegicus
Manually annotated by BRENDA team
Kelmer-Bracht, A.M.; Santos, C.P.; Ishii-Iwamoto, E.L.; Broetto-Biazon, A.C.; Bracht, A.
Kinetic properties of the glucose 6-phosphatase of the liver from arthritic rats
Biochim. Biophys. Acta
1638
50-56
2003
Rattus norvegicus
Manually annotated by BRENDA team
Madsen, P.; Jakobsen, P.; Westergaard, N.
N,N-dibenzyl-N'-benzylidenehydrazines: potent competitive glucose-6-phosphatase catalytic enzyme inhibitors
Bioorg. Med. Chem. Lett.
11
2165-2167
2001
Sus scrofa
Manually annotated by BRENDA team
Westergaard, N.; Madsen, P.; Lundbeck, J.M.; Jakobsen, P.; Varming, A.; Andersen, B.
Identification of two novel and potent competitive inhibitors of the glucose-6-phosphatase catalytic protein
Diabetes Obes Metab.
24
96-105
2002
Rattus norvegicus, Sus scrofa
-
Manually annotated by BRENDA team
Foster, J.D.; Nordlie, R.C.
The biochemistry and molecular biology of the glucose-6-phosphatase system
Exp. Biol. Med.
227
601-608
2002
Homo sapiens
Manually annotated by BRENDA team
Guionie, O.; Clottes, E.; Stafford, K.; Burchell, A.
Identification and characterisation of a new human glucose-6-phosphatase isoform
FEBS Lett.
551
159-164
2003
Rattus norvegicus, Homo sapiens (Q9BUM1), Homo sapiens
Manually annotated by BRENDA team
Ghosh, A.; Shieh, J.J.; Pan, C.J.; Sun, M.S.; Chou, J.Y.
The Catalytic Center of Glucose-6-phosphatase
J. Biol. Chem.
277
32837-32842
2002
Homo sapiens
Manually annotated by BRENDA team
Shieh, J.J.; Terzioglu, M.; Hiraiwa, H.; Marsh, J.; Pan, C.J.; Chen, L.Y.; Chou, J.Y.
The molecular basis of glycogen storage disease type 1a: structure and function analysis of mutations in glucose-6-phosphatase
J. Biol. Chem.
277
5047-5053
2002
Homo sapiens
Manually annotated by BRENDA team
Ghosh, A.; Shieh, J.J.; Pan, C.J.; Chou, J.Y.
Histidine 167 is the phosphate acceptor in glucose-6-phosphatase-b forming a phosphohistidine enzyme intermediate during catalysis
J. Biol. Chem.
279
12479-12483
2004
Homo sapiens
Manually annotated by BRENDA team
Plewka, A.; Kaminski, M.; Plewka, D.; Nowaczyk, G.
Glucose-6-phosphatase and age: biochemical and histochemical studies
Mech. Ageing Dev.
113
49-59
2000
Rattus norvegicus
Manually annotated by BRENDA team
Hornbuckle, L.A.; Everett, C.A.; Martin, C.C.; Gustavson, S.S.; Svitek, C.A.; Oeser, J.K.; Neal, D.W.; Cherrington, A.D.; O'Brien, R.M.
Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ
Am. J. Physiol.
286
E795-E808
2004
Canis lupus familiaris
Manually annotated by BRENDA team
Meton, I.; Caseras, A.; Fernandez, F.; Baanante, I.V.
Molecular cloning of hepatic glucose-6-phosphatase catalytic subunit from gilthead sea bream (Sparus aurata): response of its mRNA levels and glucokinase expression to refeeding and diet composition
Comp. Biochem. Physiol. B
138
145-153
2004
Sparus aurata (Q98UF8), Sparus aurata
Manually annotated by BRENDA team
Kuang, Y.; Schomisch, S.J.; Chandramouli, V.; Lee, Z.
Hexokinase and glucose-6-phosphatase activity in woodchuck model of hepatitis virus-induced hepatocellular carcinoma
Comp. Biochem. Physiol. C
143
225-231
2006
Marmota monax
Manually annotated by BRENDA team
Wang, D.; Wei, Y.; Schmoll, D.; Maclean, K.N.; Pagliassotti, M.J.
Endoplasmic reticulum stress increases glucose-6-phosphatase and glucose cycling in liver cells
Endocrinology
147
350-358
2006
Rattus norvegicus
Manually annotated by BRENDA team
Jang, W.; Gomer, R.H.
Exposure of cells to a cell number-counting factor decreases the activity of glucose-6-phosphatase to decrease intracellular glucose levels in Dictyostelium discoideum
Eukaryot. Cell
4
72-81
2005
Dictyostelium discoideum
Manually annotated by BRENDA team
Ghosh, A.; Cheung, Y.Y.; Mansfield, B.C.; Chou, J.Y.
Brain contains a functional glucose-6-phosphatase complex capable of endogenous glucose production
J. Biol. Chem.
280
11114-11119
2005
Mus musculus
Manually annotated by BRENDA team
Angaroni, C.J.; de Kremer, R.D.; Argarana, C.E.; Paschini-Capra, A.E.; Giner-Ayala, A.N.; Pezza, R.J.; Pan, C.J.; Chou, J.Y.
Glycogen storage disease type Ia in Argentina: two novel glucose-6-phosphatase mutations affecting protein stability
Mol. Genet. Metab.
83
276-279
2004
Homo sapiens (P35575), Homo sapiens
Manually annotated by BRENDA team
Kuang, Y.; Schomisch, S.J.; Chandramouli, V.; Lee, Z.
Hexokinase and glucose-6-phosphatase activity in woodchuck model of hepatitis virus-induced hepatocellular carcinoma
Comp. Biochem. Physiol. C
143C
225-231
2006
Marmota monax
-
Manually annotated by BRENDA team
Pedersen, K.B.; Zhang, P.; Doumen, C.; Charbonnet, M.; Lu, D.; Newgard, C.B.; Haycock, J.W.; Lange, A.J.; Scott, D.K.
The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions
Am. J. Physiol. Endocrinol. Metab.
292
E788-E801
2007
Rattus norvegicus
Manually annotated by BRENDA team
Guigas, B.; Naboulsi, R.; Villanueva, G.R.; Taleux, N.; Lopez-Novoa, J.E.; Leverve, X.M.; El-Mir, M.Y.
The flavonoid silibinin decreases glucose-6-phosphate hydrolysis in perfused rat hepatocytes by an inhibitory effect on glucose-6-phosphatase
Cell. Physiol. Biochem.
20
925-934
2007
Rattus norvegicus
Manually annotated by BRENDA team
Enes, P.; Panserat, S.; Kaushik, S.; Oliva-Teles, A.
Hepatic glucokinase and glucose-6-phosphatase responses to dietary glucose and starch in gilthead sea bream (Sparus aurata) juveniles reared at two temperatures
Comp. Biochem. Physiol. A
149
80-86
2008
Sparus aurata, Sparus aurata (Q98UF8)
Manually annotated by BRENDA team
Csala, M.; Margittai, E.; Senesi, S.; Gamberucci, A.; Banhegyi, G.; Mandl, J.; Benedetti, A.
Inhibition of hepatic glucose 6-phosphatase system by the green tea flavanol epigallocatechin gallate
FEBS Lett.
581
1693-1698
2007
Rattus norvegicus
Manually annotated by BRENDA team
Jang, W.; Gomer, R.H.
A protein in crude cytosol regulates glucose-6-phosphatase activity in crude microsomes to regulate group size in Dictyostelium
J. Biol. Chem.
281
16377-16383
2006
Dictyostelium discoideum
Manually annotated by BRENDA team
Yang, J.; Danke, N.A.; Berger, D.; Reichstetter, S.; Reijonen, H.; Greenbaum, C.; Pihoker, C.; James, E.A.; Kwok, W.W.
Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects
J. Immunol.
176
2781-2789
2006
Homo sapiens
Manually annotated by BRENDA team
Onuma, H.; Oeser, J.K.; Nelson, B.A.; Wang, Y.; Flemming, B.P.; Scheving, L.A.; Russell, W.E.; OBrien, R.M.
Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms
Biochem. J.
417
611-620
2009
Mus musculus
Manually annotated by BRENDA team
Enes, P.; Panserat, S.; Kaushik, S.; Oliva-Teles, A.
Rearing temperature enhances hepatic glucokinase but not glucose-6-phosphatase activities in European sea bass (Dicentrarchus labrax) and gilthead sea bream (Sparus aurata) juveniles fed with the same level of glucose
Comp. Biochem. Physiol. A
150
355-358
2008
Dicentrarchus labrax, Sparus aurata (Q8AYI6)
Manually annotated by BRENDA team
Wang, Y.; Flemming, B.P.; Martin, C.C.; Allen, S.R.; Walters, J.; Oeser, J.K.; Hutton, J.C.; OBrien, R.M.
Long-range enhancers are required to maintain expression of the autoantigen islet-specific glucose-6-phosphatase catalytic subunit-related protein in adult mouse islets in vivo
Diabetes
57
133-141
2008
Mus musculus
Manually annotated by BRENDA team
Schilling, M.M.; Oeser, J.K.; Chandy, J.K.; Flemming, B.P.; Allen, S.R.; OBrien, R.M.
Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1alpha
Diabetologia
51
1505-1514
2008
Mus musculus (P35576), Mus musculus
Manually annotated by BRENDA team
Chen, S.; Pan, C.; Nandigama, K.; Mansfield, B.C.; Ambudkar, S.V.; Chou, J.Y.
The glucose-6-phosphate transporter is a phosphate-linked antiporter deficient in glycogen storage disease type Ib and Ic
FASEB J.
22
2206-2213
2008
Homo sapiens (P35575)
Manually annotated by BRENDA team
Kuo, M.; Zilberfarb, V.; Gangneux, N.; Christeff, N.; Issad, T.
O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene
FEBS Lett.
582
829-834
2008
Homo sapiens
Manually annotated by BRENDA team
Chou, J.Y.; Mansfield, B.C.
Mutations in the glucose-6-phosphatase-alpha (G6PC) gene that cause type Ia glycogen storage disease
Hum. Mutat.
29
921-930
2008
Homo sapiens (P35575), Homo sapiens
Manually annotated by BRENDA team
Hirota, K.; Sakamaki, J.; Ishida, J.; Shimamoto, Y.; Nishihara, S.; Kodama, N.; Ohta, K.; Yamamoto, M.; Tanimoto, K.; Fukamizu, A.
A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding
J. Biol. Chem.
283
32432-32441
2008
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Chen, W.M.; Erdos, M.R.; Jackson, A.U.; Saxena, R.; Sanna, S.; Silver, K.D.; Timpson, N.J.; Hansen, T.; Orru, M.; Grazia Piras, M.; Bonnycastle, L.L.; Willer, C.J.; Lyssenko, V.; Shen, H.; Kuusisto, J.; Ebrahim, S.; Sestu, N.; Duren, W.L.; Spada, M.C.; Stringham, H.M.; Scott, L.J.; Olla, N.; Swift, A.J.; Najjar, S.; Mitchell, B.D.; Lawlor, D.A.; Smith, G.D.; Ben-Shlomo, Y.; Andersen, G.; Borch-Johnsen, K.; Jrgensen, T.; Saramies, J.; Valle, T.T.; Buchanan, T.A.; Shuldiner, A.R.; Lakatta, E.; Bergman, R.N.; Uda, M.; Tuomilehto, J.; Pedersen, O.; Cao, A.; Groop, L.; Mohlke, K.L.; Laakso, M.; Schlessinger, D.; Collins, F.S.; Altshuler, D.; Abecasis, G.R.; Boehnke, M.; Scuteri, A.; Watanabe, R.M.
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
J. Clin. Invest.
118
2620-2628
2008
Homo sapiens (Q9NQR9)
Manually annotated by BRENDA team
Martin, C.C.; Flemming, B.P.; Wang, Y.; Oeser, J.K.; OBrien, R.M.
Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression
J. Mol. Endocrinol.
41
315-328
2008
Mus musculus (Q9Z186), Mus musculus
Manually annotated by BRENDA team
Bouatia-Naji, N.; Rocheleau, G.; Van Lommel, L.; Lemaire, K.; Schuit, F.; Cavalcanti-Proenca, C.; Marchand, M.; Hartikainen, A.L.; Sovio, U.; De Graeve, F.; Rung, J.; Vaxillaire, M.; Tichet, J.; Marre, M.; Balkau, B.; Weill, J.; Elliott, P.; Jarvelin, M.R.; Meyre, D.; Polychronakos, C.; Dina, C.; Sladek, R.; Froguel, P.
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
Science
320
1085-1088
2008
Homo sapiens
Manually annotated by BRENDA team
Modi, H.R.; Patil, N.; Katyare, S.S.
Effect of treatment with cadmium on kinetic properties of Na(+), K(+)-ATPase and glucose-6-phosphatase activity in rat liver microsomes a correlative study on influence of lipid/phospholipid make-up
Toxicology
254
29-41
2008
Rattus norvegicus
Manually annotated by BRENDA team
Ota, S.; Horigome, K.; Ishii, T.; Nakai, M.; Hayashi, K.; Kawamura, T.; Kishino, A.; Taiji, M.; Kimura, T.
Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism
Biochem. Biophys. Res. Commun.
388
311-316
2009
Rattus norvegicus
Manually annotated by BRENDA team
Lindbloom, S.; LeCluyse, M.; Schermerhorn, T.
Cloning and comparative bioinformatic analysis of feline glucose-6-phosphatase catalytic subunit cDNA
DNA Seq.
19
256-263
2008
Felis catus (Q19KA1), Felis catus
Manually annotated by BRENDA team
Nozdrachev, A.; Telushkin, P.
Liver glucose-6-phosphatase activity and blood fatty acid level in rats with insulin-induced hypoglycemia
Dokl. Biol. Sci.
422
294-295
2008
Rattus norvegicus
Manually annotated by BRENDA team
Kumar, M.; Rawat, P.; Khan, M.F.; Tamarkar, A.K.; Srivastava, A.K.; Arya, K.R.; Maurya, R.
Phenolic glycosides from Dodecadenia grandiflora and their glucose-6-phosphatase inhibitory activity
Fitoterapia
81
475-479
2010
Rattus norvegicus
Manually annotated by BRENDA team
Henry-Vitrac, C.; Ibarra, A.; Roller, M.; Merillon, J.M.; Vitrac, X.
Contribution of chlorogenic acids to the inhibition of human hepatic glucose-6-phosphatase activity in vitro by Svetol, a standardized decaffeinated green coffee extract
J. Agric. Food Chem.
58
4141-4144
2010
Homo sapiens
Manually annotated by BRENDA team
Hutton, J.C.; OBrien, R.M.
Glucose-6-phosphatase catalytic subunit gene family
J. Biol. Chem.
284
29241-29245
2009
Homo sapiens
Manually annotated by BRENDA team
Lord-Dufour, S.; Copland, I.B.; Levros, L.C.; Post, M.; Das, A.; Khosla, C.; Galipeau, J.; Rassart, E.; Annabi, B.
Evidence for transcriptional regulation of the glucose-6-phosphate transporter by HIF-1alpha: Targeting G6PT with mumbaistatin analogs in hypoxic mesenchymal stromal cells
Stem Cells
27
489-497
2009
Mus musculus
Manually annotated by BRENDA team
Joshi, A.K.; Rajini, P.S.
Reversible hyperglycemia in rats following acute exposure to acephate, an organophosphorus insecticide: role of gluconeogenesis
Toxicology
257
40-45
2009
Rattus norvegicus
Manually annotated by BRENDA team
Barfell, A.; Crumbly, A.; Romani, A.
Enhanced glucose 6-phosphatase activity in liver of rats exposed to Mg(2+)-deficient diet
Arch. Biochem. Biophys.
509
157-163
2011
Rattus norvegicus
Manually annotated by BRENDA team
Hayee, B.; Antonopoulos, A.; Murphy, E.J.; Rahman, F.Z.; Sewell, G.; Smith, B.N.; McCartney, S.; Furman, M.; Hall, G.; Bloom, S.L.; Haslam, S.M.; Morris, H.R.; Boztug, K.; Klein, C.; Winchester, B.; Pick, E.; Linch, D.C.; Gale, R.E.; Smith, A.M.; Dell, A.; Segal, A.W.
G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction
Glycobiology
21
914-924
2011
Homo sapiens
Manually annotated by BRENDA team
Mahato, A.; Bhattacharya, S.; Shanthi, N.
Design, synthesis and glucose-6-phosphatase inhibitory activity of diaminoguanidine analogues of 3-guanidinopropionic acid and amino substituted (pyridin-2-yl)thiourea derivatives
J. Pharm. Sci. Res.
3
896-902
2011
Capra hircus
-
Manually annotated by BRENDA team
Konopelska, S.; Kienitz, T.; Quinkler, M.
Downregulation of Hepatic Glucose-6-Phosphatase-alpha in Patients With Hepatic Steatosis
Obesity (Silver Spring)
19
2322-2326
2011
Homo sapiens
Manually annotated by BRENDA team
Shehzad, S.
The potential effect of vanadium compounds on glucose-6-phosphatase
Biosci. Horizons
6
hzt002
2013
Bos taurus
-
Manually annotated by BRENDA team
Moraes-Silva, L.; Bueno, T.M.; Franciscato, C.; de Oliveira, C.S.; Peixoto, N.C.; Pereira, M.E.
Mercury chloride increases hepatic alanine aminotransferase and glucose 6-phosphatase activities in newborn rats in vivo
Cell Biol. Int.
36
561-566
2012
Rattus norvegicus
Manually annotated by BRENDA team
Abbadi, S.; Rodarte, J.J.; Abutaleb, A.; Lavell, E.; Smith, C.L.; Ruff, W.; Schiller, J.; Olivi, A.; Levchenko, A.; Guerrero-Cazares, H.; Quinones-Hinojosa, A.
Glucose-6-phosphatase is a key metabolic regulator of glioblastoma invasion
Mol. Cancer Res.
12
1547-1559
2014
Homo sapiens
Manually annotated by BRENDA team
Jeon, J.Y.; Lee, H.; Park, J.; Lee, M.; Park, S.W.; Kim, J.S.; Lee, M.; Cho, B.; Kim, K.; Choi, A.M.; Kim, C.K.; Yun, M.
The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells
Biochem. Biophys. Res. Commun.
463
440-446
2015
Homo sapiens
Manually annotated by BRENDA team
Yoshida, M.; Lee, E.Y.; Kohno, T.; Tanaka, T.; Miyazaki, M.; Miki, T.
Importance of hepatocyte nuclear factor 4alpha in glycerol-induced glucose-6-phosphatase expression in liver
Biomed. Res.
37
85-93
2016
Rattus norvegicus (P43428)
Manually annotated by BRENDA team
Mueller, M.S.; Fouyssac, M.; Taylor, C.W.
Effective glucose uptake by human astrocytes requires its sequestration in the endoplasmic reticulum by glucose-6-phosphatase-beta
Curr. Biol.
28
3481-3486
2018
Homo sapiens
Manually annotated by BRENDA team
Soty, M.; Chilloux, J.; Delalande, F.; Zitoun, C.; Bertile, F.; Mithieux, G.; Gautier-Stein, A.
Post-translational regulation of the glucose-6-phosphatase complex by cyclic adenosine monophosphate is a crucial determinant of endogenous glucose production and is controlled by the glucose-6-phosphate transporter
J. Proteome Res.
15
1342-1349
2016
Homo sapiens (P35575)
Manually annotated by BRENDA team
Singh, P.; Han, E.H.; Endrizzi, J.A.; OBrien, R.M.; Chi, Y.I.
Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter
J. Struct. Biol.
198
54-64
2017
Homo sapiens
Manually annotated by BRENDA team
Lee, Y.M.; Kim, G.Y.; Pan, C.J.; Mansfield, B.C.; Chou, J.Y.
Minimal hepatic glucose-6-phosphatase-alpha activity required to sustain survival and prevent hepatocellular adenoma formation in murine glycogen storage disease type Ia
Mol. Genet. Metab. Rep.
3
28-32
2015
Mus musculus
Manually annotated by BRENDA team