3.1.3.9: glucose-6-phosphatase

This is an abbreviated version!
For detailed information about glucose-6-phosphatase, go to the full flat file.

Word Map on EC 3.1.3.9

3.1.3.9

glycogen

gluconeogenesis

phosphoenolpyruvate

carboxykinase

hepatocytes

pepck

gluconeogenic

hyperglycemia

glucokinase

hexokinase

triglyceride

cholesterol

succinate

fructose

wistar

glucagon

mellitus

pancreatic

streptozotocin

high-fat

antidiabetic

cytochemical

5'-nucleotidase

hypoglycemic

streptozotocin-induced

fructose-1,6-bisphosphatase

glycogenolysis

metformin

amp-activated

transpeptidase

periportal

preneoplastic

phosphofructokinase

translocase

lipogenesis

hepatocarcinogenesis

ccl4

hepatomegaly

antihyperglycemic

triphosphatase

gamma-glutamyl

forkhead

perivenous

chrebp

medicine

fbpase

glycogenesis

diethylnitrosamine

hyperuricemia

1,6-bisphosphatase

cytochemistry

Reaction

D-glucose 6-phosphate

+

H2O

=

D-glucose

+

phosphate

Synonyms

D-glucose-6-phosphate phosphorylase, G-6-Pase, G6Pase, G6Pase-alpha, G6Pase-beta, G6PC, G6PC-2, G6PC-3, G6Pc1, G6PC2, Glc-6-P phosphohydrolase, Glc-6-Pase-alpha, Glc-6-Pase-beta, glucose 6-phosphatase, glucose 6-phosphate phosphatase, glucose 6-phosphate phosphohydrolase, glucose-6-phosphatase, glucose-6-phosphatase catalytic subunit 2, glucose-6-phosphatase catalytic subunit-related protein, glucose-6-phosphatase catalytic unit 2, glucose-6-phosphatase-alpha, glucose-6-phosphatase-beta, IGRP, islet-specific glucose-6-phosphatase catalytic subunit-related protein, islet-specific glucose-6-phosphatase-related protein, phosphatase, glucose 6-

ECTree

3.1 Acting on ester bonds

3.1.3 Phosphoric-monoester hydrolases

3.1.3.9 glucose-6-phosphatase

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Results	in table
31	Activating Compound
2069	AA Sequence
13	Application
1	CAS Registry Number
20	Cloned(Commentary)
1	Crystallization (Commentary)
2601	Disease/ Diagnostics
4	Expression
6	General Information
3	General Stability
17	IC50 Value
122	Inhibitors
34	Ki Value [mM]
63	KM Value [mM]
84	Localization
3	Metals/Ions
11	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
218	Organism
1	Oxidation Stability
6	Pathway
21	pH Optimum
1	pH Range
2	pH Stability
1	pI Value
3	Posttranslational Modification
51	Protein Variants
16	Purification (Commentary)
6	Reaction
1	Reaction Type
213	Reference
401	Source Tissue
34	Specific Activity [micromol/min/mg]
3	Storage Stability
269	Substrates and Products (Substrate)
13	Subunits
83	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
5	Temperature Stability [°C]
1	Turnover Number [1/s]

KI Value

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KI Value on EC 3.1.3.9 - glucose-6-phosphatase

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2

2-nitro-5-thiocyano-benzoic acid

Rattus norvegicus

-

-

0.00128

3,4-dichlorobenzaldehyde dibenzylhydrazone

-

-

0.00045

3-methoxybenzaldehyde dibenzylhydrazone

-

-

0.035

4,4'-di-isothiocyanostilbene-2,2'-disulphonate

-

-

0.00015

4-chlorobenzaldehyde dibenzylhydrazone

-

-

0.00154

4-hydroxybenzaldehyde dibenzylhydrazone

-

-

0.5

4-maleimidylstilbene-2,2'-disulfonic acid

Rattus norvegicus

-

-

0.00014

4-methoxybenzaldehyde dibenzylhydrazone

-

-

0.00027 - 0.0033

4-methoxyphenyl-[4-(4-methoxyphenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl]methanone

show

0.00029 - 0.004

4-methoxyphenyl-[4-(4-trifluoromethoxyphenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl]methanone

show

0.8

5-((((iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid

Rattus norvegicus

-

-

0.00011

5-chlorotetrahydrothiophene-2-carbaldehyde dibenzylhydrazone

-

-

0.021

5-ethyltetrahydrofuran-2-carbaldehyde dibenzylhydrazone

-

-

0.00096

benzaldehyde dibenzylhydrazone

-

-

0.5

chlorogenic acid

-

-

50 - 200

D-glucose

-

-

0.6

DTNB

Rattus norvegicus

-

-

0.011

isonicotinaldehyde dibenzylhydrazone

-

-

0.5

NEM

Rattus norvegicus

-

-

0.237

nicotinaldehyde dibenzylhydrazone

-

-

0.0064

pyridine-2-carbaldehyde dibenzylhydrazone

-

-

0.000704

tetrahydrofuran-2-carbaldehyde dibenzylhydrazone

-

-

0.00096

tetrahydrothiophene-2-carbaldehyde dibenzylhydrazone

-

-

0.001 - 0.025

tungstate

show

0.0022 - 0.0056

vanadate

show

additional information

additional information

-

-

-

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Release 2023.1 (January 2023)