2.7.1.151: inositol-polyphosphate multikinase

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For detailed information about inositol-polyphosphate multikinase, go to the full flat file.

Word Map on EC 2.7.1.151

2.7.1.151

phosphatidylinositol

phospholipase

phosphoinositide

4,5-bisphosphate

4-phosphate

5-phosphatase

1,3,4,5-tetrakisphosphate

bacteriorhodopsin

insp3

pip2

ptdins4,5p2

4-kinase

hexakisphosphate

pikfyve

ptdins4p

pentakisphosphate

1,3,4-trisphosphate

3hinositol

phosphatidylinositol-4-phosphate

photocycle

diphosphoinositol

inositide

3,4,5-trisphosphate

5/6-kinase

polyphosphoinositide

medicine

light-driven

arf6

agriculture

Reaction

1D-myo-inositol 1,4,5,6-tetrakisphosphate

1D-myo-inositol 1,3,4,5,6-pentakisphosphate

Synonyms

1,3,4,6-tetrakisphosphate 5-kinase, 5-kinase, Arg82, ArgRIII, ARGSIII, AtIpk2a, AtIpk2b, AtIpk2beta, HsIPMK, Impk, inositol 1,4,5-trisphosphate 3-kinase, inositol phosphate multikinase, inositol phosphate multikinase 2, inositol polyphosphate 6-/3-kinase, inositol polyphosphate kinase, inositol polyphosphate multikinase, Ins(1,4,5)P3 3-kinase, InsP4 5-kinase, IP3 3-kinase, IP3/IP4 6-/3-kinase, IP3K, IPK, Ipk2, Ipk2/Impk/IP3K, Ipk2a, Ipk2beta/IP3K, IPKII, IPMK, ITPK1, Kcs1, Kcs1p, More, phosphoinositol kinase, PI3K, StIPMK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.151 inositol-polyphosphate multikinase

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Results	in table
5	Activating Compound
564	AA Sequence
8	Application
1	CAS Registry Number
26	Cloned(Commentary)
23	Cofactor
4	Crystallization (Commentary)
90	Disease/ Diagnostics
16	General Information
1	General Stability
7	IC50 Value
15	Inhibitors
8	kcat/KM [mM/s]
2	Ki Value [mM]
31	KM Value [mM]
16	Localization
21	Metals/Ions
6	Molecular Weight [Da]
79	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
46	Organism
5	Pathway
18	PDB ID
11	pH Optimum
9	Posttranslational Modification
36	Protein Variants
11	Purification (Commentary)
4	Reaction
9	Reaction Type
45	Reference
52	Source Tissue
17	Specific Activity [micromol/min/mg]
134	Substrates and Products (Substrate)
8	Subunits
109	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Stability [°C]

Organism

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Organism on EC 2.7.1.151 - inositol-polyphosphate multikinase

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Arabidopsis thaliana

8 entries

Drosophila melanogaster

Like the yeast enzyme, mammalian, plant and fly orthologs share the capacity for the conversion of Ins(1,4,5)P3 to Ins(1,3,4,5,6)P5. Plant and fly IPMKs recapitulate the yeast enzyme's preference for D6-hydroxyl phoshorylation followed by D3-hydroxylphosphorylation, mammalian IPMKs appear to prefer the reverse order.

white leghorn chick

Saccharomyces cerevisiae

4 entries

Solanum tuberosum

2 entries