2.7.1.151: inositol-polyphosphate multikinase

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For detailed information about inositol-polyphosphate multikinase, go to the full flat file.

Word Map on EC 2.7.1.151

2.7.1.151

phosphatidylinositol

phospholipase

phosphoinositide

4,5-bisphosphate

4-phosphate

5-phosphatase

1,3,4,5-tetrakisphosphate

bacteriorhodopsin

insp3

pip2

ptdins4,5p2

4-kinase

hexakisphosphate

pikfyve

ptdins4p

pentakisphosphate

1,3,4-trisphosphate

3hinositol

phosphatidylinositol-4-phosphate

photocycle

diphosphoinositol

inositide

3,4,5-trisphosphate

5/6-kinase

polyphosphoinositide

medicine

light-driven

arf6

agriculture

Reaction

1D-myo-inositol 1,4,5,6-tetrakisphosphate

1D-myo-inositol 1,3,4,5,6-pentakisphosphate

Synonyms

1,3,4,6-tetrakisphosphate 5-kinase, 5-kinase, Arg82, ArgRIII, ARGSIII, AtIpk2a, AtIpk2b, AtIpk2beta, HsIPMK, Impk, inositol 1,4,5-trisphosphate 3-kinase, inositol phosphate multikinase, inositol phosphate multikinase 2, inositol polyphosphate 6-/3-kinase, inositol polyphosphate kinase, inositol polyphosphate multikinase, Ins(1,4,5)P3 3-kinase, InsP4 5-kinase, IP3 3-kinase, IP3/IP4 6-/3-kinase, IP3K, IPK, Ipk2, Ipk2/Impk/IP3K, Ipk2a, Ipk2beta/IP3K, IPKII, IPMK, ITPK1, Kcs1, Kcs1p, More, phosphoinositol kinase, PI3K, StIPMK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.151 inositol-polyphosphate multikinase

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Results	in table
5	Activating Compound
564	AA Sequence
8	Application
1	CAS Registry Number
26	Cloned(Commentary)
23	Cofactor
4	Crystallization (Commentary)
90	Disease/ Diagnostics
16	General Information
1	General Stability
7	IC50 Value
15	Inhibitors
8	kcat/KM [mM/s]
2	Ki Value [mM]
31	KM Value [mM]
16	Localization
21	Metals/Ions
6	Molecular Weight [Da]
79	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
46	Organism
5	Pathway
18	PDB ID
11	pH Optimum
9	Posttranslational Modification
36	Protein Variants
11	Purification (Commentary)
4	Reaction
9	Reaction Type
45	Reference
52	Source Tissue
17	Specific Activity [micromol/min/mg]
134	Substrates and Products (Substrate)
8	Subunits
109	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Stability [°C]

KM Value

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KM Value on EC 2.7.1.151 - inositol-polyphosphate multikinase

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0.00013 - 0.568

1D-myo-inositol 1,3,4,5-tetrakisphosphate

5 entries

0.0003

1D-myo-inositol 1,3,4,6-tetrakisphosphate

Homo sapiens

recombinant enzyme, pH 7.2, 37°C

640974, 660926

0.00022 - 0.254

1D-myo-inositol 1,4,5,6-tetrakisphosphate

5 entries

0.00011 - 0.162

1D-myo-inositol 1,4,5-trisphosphate

7 entries

0.006 - 0.03

1D-myo-inositol 4,5-bisphosphate

2 entries

0.000222

1D-myo-inositol-1,4,5,6-tetrakisphosphate

Homo sapiens

37°C, pH 7.2

660926

0.017 - 0.039

ATP

2 entries

0.000129

inositol (1,3,4,5)-tetrakisphosphate

Homo sapiens

37°C, pH 7.2

660926

0.000295

inositol (1,3,4,6)-tetrakisphosphate

Homo sapiens

37°C, pH 7.2

660926

0.000112

inositol (1,4,5)-trisphosphate

Homo sapiens

37°C, pH 7.2

660926

0.00018

inositol (1,4,5,6)-tetrakisphosphate

Homo sapiens

673651

additional information

Homo sapiens

kinetics

640974