2.7.1.151: inositol-polyphosphate multikinase

This is an abbreviated version!
For detailed information about inositol-polyphosphate multikinase, go to the full flat file.

Reaction

Synonyms

1,3,4,6-tetrakisphosphate 5-kinase, 5-kinase, Arg82, ArgRIII, ARGSIII, AtIpk2a, AtIpk2b, AtIpk2beta, HsIPMK, Impk, inositol 1,4,5-trisphosphate 3-kinase, inositol phosphate multikinase, inositol phosphate multikinase 2, inositol polyphosphate 6-/3-kinase, inositol polyphosphate kinase, inositol polyphosphate multikinase, Ins(1,4,5)P3 3-kinase, InsP4 5-kinase, IP3 3-kinase, IP3/IP4 6-/3-kinase, IP3K, IPK, Ipk2, Ipk2/Impk/IP3K, Ipk2a, Ipk2beta/IP3K, IPKII, IPMK, ITPK1, Kcs1, Kcs1p, More, phosphoinositol kinase, PI3K, StIPMK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.151 inositol-polyphosphate multikinase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
5	Activating Compound
564	AA Sequence
8	Application
1	CAS Registry Number
26	Cloned(Commentary)
23	Cofactor
4	Crystallization (Commentary)
90	Disease/ Diagnostics
16	General Information
1	General Stability
7	IC50 Value
15	Inhibitors
8	kcat/KM [mM/s]
2	Ki Value [mM]
31	KM Value [mM]
16	Localization
21	Metals/Ions
6	Molecular Weight [Da]
79	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
46	Organism
5	Pathway
18	PDB ID
11	pH Optimum
9	Posttranslational Modification
36	Protein Variants
11	Purification (Commentary)
4	Reaction
9	Reaction Type
45	Reference
52	Source Tissue
17	Specific Activity [micromol/min/mg]
134	Substrates and Products (Substrate)
8	Subunits
109	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Stability [°C]

IC50 Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

IC50 Value on EC 2.7.1.151 - inositol-polyphosphate multikinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to IC50 Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.000044

aurintricarboxylic acid

Homo sapiens

-

mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate, strong inhibition, IC50 is 44 nM

662346

0.0012

chlorogenic acid

Homo sapiens

-

mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate, slight inhibition, IC50 is 0.0012 mM

662346

0.0014

ellagic acid

Homo sapiens

-

mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate, slight inhibition, IC50 is 0.0014 mM

662346

0.0034

gossypol

Homo sapiens

-

mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate, slight inhibition, IC50 is 0.0034 mM

662346

0.0076

inositol(1,3,4)-trisphosphate

Homo sapiens

-

potently inhibits hITPK1 activity towards insositol (3,4,5,6)-tetrakisphosphate, IC50: 0.0076 mM

673651

0.1

inositol(3,5,6)-trisphosphate

Homo sapiens

-

IC50: 0.1 mM

673651

0.00062

Rose bengal

Homo sapiens

-

mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate, slight inhibition, IC50 is 620 nM

662346