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Literature summary for 2.7.1.151 extracted from
- Metabolism of inositol phosphates. Part XIV. Evidence for the existence of a phosphoinositol kinase in chicken erythrocytes (1981), Indian J. Biochem. Biophys., 18, 398-401.
General Stability
| General Stability | Organism |
|---|---|
| 2-mercaptoethanol or other -SH containing compounds protect the enzyme | Gallus gallus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | absolutely required for activity | Gallus gallus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myo-inositol triphosphate + ATP | Gallus gallus | it appears that the enzyme utilizes inositol triphosphate as the initial substrate for the synthesis of higher myo-inositol polyphosphates | myo-inositol tetrakisphosphate + ADP | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
white leghorn chick | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonuium sulfate, DEAE-cellulose | Gallus gallus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | erythrocyte | Gallus gallus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0085 | - |
- |
Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myo-inositol tetrakisphosphate + ATP | - |
Gallus gallus | myo-inositol pentakisphosphate + ADP | - |
? | |
| myo-inositol triphosphate + ATP | it appears that the enzyme utilizes inositol triphosphate as the initial substrate for the synthesis of higher myo-inositol polyphosphates | Gallus gallus | myo-inositol tetrakisphosphate + ADP | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Gallus gallus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | can be partly replaced by dATP and UTP | Gallus gallus | |
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Release 2023.1 (January 2023)
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