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Information on EC 2.3.1.135 - phosphatidylcholine-retinol O-acyltransferase

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IUBMB Comments
A key enzyme in retinoid metabolism, catalysing the transfer of an acyl group from the sn-1 position of phosphatidylcholine to retinol, forming retinyl esters which are then stored. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein, but has higher affinity for the bound form. Can also esterify 11-cis-retinol.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
lecithin retinol acyltransferase, lecithin-retinol acyltransferase, lecithin retinol acyl transferase, lecithin:retinol acyl transferase, lecithin/retinol acyltransferase, retinyl ester synthase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
phosphatidylcholine + retinol-[cellular-retinol-binding-protein] = 2-acylglycerophosphocholine + retinyl-ester-[cellular-retinol-binding-protein]
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