Cloned (Comment) | Organism |
---|---|
inducible expression of LRAT in HEK-293S cells | Mus musculus |
inducible expression of LRAT in HEK-293S cells | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
retinylamine | - |
Bos taurus | |
retinylamine | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | LRAT plays an essential role in the regeneration of visual chromophore as well as in the metabolism of vitamin A, and is responsible for amidation of retinylamine, a potent and selective inhibitor of the retinoid cycle and 11-cis-retinal biosynthesis | ? | - |
? | |
additional information | Mus musculus | LRAT plays an essential role in the regeneration of visual chromophore as well as in the metabolism of vitaminA, and is responsible for amidation of retinylamine, a potent and selective inhibitor of the retinoid cycle and 11-cis-retinal biosynthesis | ? | - |
? | |
phosphatidylcholine + all-trans-retinol | Bos taurus | LRAT catalyzes the transfer of an acyl group from the sn-1 position of phosphatidylcholine to all-trans-retinol, vitamin A | 2-acylglycerophosphocholine + all-trans-retinyl ester | - |
? | |
phosphatidylcholine + all-trans-retinol | Mus musculus | LRAT catalyzes the transfer of an acyl group from the sn-1 position of phosphatidylcholine to all-trans-retinol, vitamin A | 2-acylglycerophosphocholine + retinyl ester | - |
? | |
phosphatidylcholine + all-trans-retinylamine | Bos taurus | - |
2-acylglycerophosphocholine + all-trans-retinyl acylamide | - |
? | |
phosphatidylcholine + retinylamine | Mus musculus | - |
2-acylglycerophosphocholine + fatty acid N-retinylamide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
eye | - |
Mus musculus | - |
eye | - |
Bos taurus | - |
liver | - |
Mus musculus | - |
retinal pigment epithelium | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | LRAT plays an essential role in the regeneration of visual chromophore as well as in the metabolism of vitamin A, and is responsible for amidation of retinylamine, a potent and selective inhibitor of the retinoid cycle and 11-cis-retinal biosynthesis | Bos taurus | ? | - |
? | |
additional information | LRAT plays an essential role in the regeneration of visual chromophore as well as in the metabolism of vitaminA, and is responsible for amidation of retinylamine, a potent and selective inhibitor of the retinoid cycle and 11-cis-retinal biosynthesis | Mus musculus | ? | - |
? | |
phosphatidylcholine + all-trans-retinol | LRAT catalyzes the transfer of an acyl group from the sn-1 position of phosphatidylcholine to all-trans-retinol, vitamin A | Bos taurus | 2-acylglycerophosphocholine + all-trans-retinyl ester | - |
? | |
phosphatidylcholine + all-trans-retinol | LRAT catalyzes the transfer of an acyl group, chain length C14-C18, from the sn-1 position of phosphatidylcholine to all-trans-retinol, vitamin A | Bos taurus | 2-acylglycerophosphocholine + all-trans-retinyl ester | product identification | ? | |
phosphatidylcholine + all-trans-retinol | LRAT catalyzes the transfer of an acyl group from the sn-1 position of phosphatidylcholine to all-trans-retinol, vitamin A | Mus musculus | 2-acylglycerophosphocholine + retinyl ester | - |
? | |
phosphatidylcholine + all-trans-retinol | LRAT catalyzes the transfer of an acyl group, chain length C14-C18, from the sn-1 position of phosphatidylcholine to all-trans-retinol, vitamin A | Mus musculus | 2-acylglycerophosphocholine + retinyl ester | product identification | ? | |
phosphatidylcholine + all-trans-retinylamine | - |
Bos taurus | 2-acylglycerophosphocholine + all-trans-retinyl acylamide | - |
? | |
phosphatidylcholine + all-trans-retinylamine | - |
Bos taurus | 2-acylglycerophosphocholine + fatty acid-N-all-trans-retinyl amide | product identification | ? | |
phosphatidylcholine + retinylamine | - |
Mus musculus | 2-acylglycerophosphocholine + fatty acid N-retinylamide | - |
? | |
phosphatidylcholine + retinylamine | - |
Mus musculus | 2-acylglycerophosphocholine + fatty acid N-retinylamide | product identification | ? |
Synonyms | Comment | Organism |
---|---|---|
lecithin:retinol acyltransferase | - |
Mus musculus |
lecithin:retinol acyltransferase | - |
Bos taurus |
LRAT | - |
Mus musculus |
LRAT | - |
Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
37 | - |
assay at | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Mus musculus |
7.5 | - |
assay at | Bos taurus |