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Information on EC 1.14.15.24 - beta-carotene 3-hydroxylase

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IUBMB Comments
Requires ferredoxin and Fe(II). Also acts on other carotenoids with a beta-end group. In some species canthaxanthin is the preferred substrate.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Reaction Schemes
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+
4
reduced ferredoxin [iron-sulfur] cluster
+
2
+
2
=
+
4
oxidized ferredoxin [iron-sulfur] cluster
+
2
Synonyms
AtB1, AtB2, BCH, BCH-type carotene hydroxylase, BCH1, BCH2, beta-carotene (beta,beta-carotene) 3-hydrocylase, beta-carotene 3,3'-hydroxylases, beta-carotene 3-hydroxylase, beta-carotene hydroxylase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 = beta-cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
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(1a)
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-
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beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 = zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
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overall reaction
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beta-cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 = zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
show the reaction diagram
(1b)
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